Protein Overview: FUS1

General Information:
Name(s) found:	FUS1 / YCL027W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|18266811\|sp\|P11710.3\|FUS1_YEAST RecName: Full=Nuclear fusion protein FUS1 [NCBI NR] gi\|171537\|gb\|AAA34616.1\| FUS1 protein [Saccharomyces cerevisiae] [NCBI NR] gi\|171531\|gb\|AAA34612.1\| Fus1 fusion peptide [Saccharomyces cerevisiae] [NCBI NR] gi\|14588909\|emb\|CAA42358.2\| cell fusion protein [Saccharomyces cerevisiae] [NCBI NR] gi\|10383763\|ref\|NP_009903.2\| Membrane protein localized to the shmoo tip, required for cell fusion; expression regulated by mating pheromone; proposed to coordinate signaling, fusion, and polarization events required for fusion; potential Cdc28p substrate [NCBI NR] Nuclear fusion protein FUS1 OS=Saccharomyces cerevisiae GN=FUS1 PE=1 SV=3 [Swiss-Prot] FUS1 Cell fusion protein [mips] Membrane protein localized to the shmoo tip, required for cell fusion; expression regulated by mating pheromone; proposed to coordinate signaling, fusion, and polarization events required for fusion; potential Cdc28p substrate [SGD] FUS1, Chr III from 71803-73341 [yeast_orfs2] Chr III from 71803-73341 [yeastorf3.fasta] (P11710) Nuclear fusion protein FUS1 [4932.FASTACCERV.txt] FUS1 SGDID:S0000532, Chr III from 71803-73341, Verified ORF [yeastflysequest.fasta] Fus1p [Saccharomyces cerevisiae]gi\|14588909\|emb\|CAA42358.2\| cell fusion protein [Saccharomyces cerevisiae]gi\|18266811\|sp\|P11710\|FUS1_YEAST Nuclear fusion protein FUS1gi\|171537\|gb\|AAA34616.1\| FUS1 proteingi\|171531\|gb\|AAA34612.1\| Fus1 fusion peptide [nrdb_11152004_Chlamydomonas] FUS1 SGDID:S000000532, Chr III from 71803-73341, Verified ORF, "Membrane protein localized to the shmoo tip, required for cell fusion; expression regulated by mating pheromone; proposed to coordinate signaling, fusion, and polarization events required for [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] cell fusion protein [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Fus1 fusion peptide [nr-271106-contam.fasta] FUS1 protein [nr-271106-contam.fasta] Nuclear fusion protein FUS1 [nr-271106-contam.fasta] Membrane protein localized to the shmoo tip, required for cell fusion; expression regulated by mating pheromone; proposed to coordinate signaling, fusion, and polarization events required for fusion; potential Cdc28p substrate; Fus1p [Saccharomyces cerevi [nr-271106-contam.fasta] FUS1 SGDID:S000000532, Chr III from 71803-73341, Verified ORF, "Membrane protein localized to the shmoo tip, required for cell fusion; expression regulated by mating pheromone; proposed to coordinate signaling, fusion, and polarization events required for fusion; potential Cdc28p substrate" [yeast-bovrabprots.fasta] [chemostatdb.fasta] Nuclear fusion protein FUS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FUS1 PE=1 SV=3 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] FUS1 SGDID:S000000532, Chr III from 71803-73341, Genome Release 64-1-1, Verified ORF, "Membrane protein localized to the shmoo tip, required for cell fusion; expression regulated by mating pheromone; proposed to coordinate signaling, fusion, and polarization events required for fusion; potential Cdc28p substrate" [yeast-030211-contam.fasta] FUS1 SGDID:S000000532, Chr III from 71803-73341, Genome Release 64-2-1, Verified ORF, "Membrane protein localized to the shmoo tip; required for cell fusion; expression regulated by mating pheromone; proposed to coordinate signaling, fusion, and polarization events required for fusion; potential Cdc28p substrate" [20141208_orf_trans.fasta] YCL027W SGDID:S000000532, Chr III from 71803-73341, Genome Release 64-1-1, Verified ORF, "Membrane protein localized to the shmoo tip, required for cell fusion; expression regulated by mating pheromone; proposed to coordinate signaling, fusion, and polarization events required for fusion; potential Cdc28p substrate" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	512 amino acids
Gene Ontology:
Cellular Component:	mating projection tip [IDA] plasma membrane [IDA]
Biological Process:	conjugation with cellular fusion [IMP] regulation of termination of mating projection growth [IMP]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVATIMQTTT TVLTTVAAMS TTLASNYISS QASSSTSVTT VTTIATSIRS TPSNLLFSNV  60
   61 AAQPKSSSAS TIGLSIGLPI GIFCFGLLIL LCYFYLKRNS VSISNPPMSA TIPREEEYCR 120
  121 RTNWFSRLFW QSKCEDQNSY SNRDIEKYND TQWTSGDNMS SKIQYKISKP IIPQHILTPK 180
  181 KTVKNPYAWS GKNISLDPKV NEMEEEKVVD AFLYTKPPNI VHIESSMPSY NDLPSQKTVS 240
  241 SKKTALKTSE KWSYESPLSR WFLRGSTYFK DYGLSKTSLK TPTGAPQLKQ MKMLSRISKG 300
  301 YFNESDIMPD ERSPILEYNN TPLDANDSVN NLGNTTPDSQ ITSYRNNNID LITARPHSVI 360
  361 YGTTAQQTLE TNFNDHHDCN KSTEKHELII PTPSKPLKKR KKRRQSKMYQ HLQHLSRSKP 420
  421 LPLTPNSKYN GEASVQLGKT YTVIQDYEPR LTDEIRISLG EKVKILATHT DGWCLVEKCN 480
  481 TQKGSIHVSV DDKRYLNEDR GIVPGDCLQE YD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	FUS1	YIR014W	2	Unpublished Fields Lab Data
View Screen	FUS1	SML1	2	Unpublished Fields Lab Data
View Screen	IQG1	FUS1	2	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	FUS1	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..430]	deduced	N/A	No confident structure predictions are available.
2	View Details	[431..512]	Pfam	3.638272	SH3 domain No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2