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Protein Overview: YKR078W

General Information:
Name(s) found: YKR078W [SGD]
Description(s) found:
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  • gi|6322931|ref|NP_013004.1| Cytoplasmic protein of unknown function, has similarity to Vps5p; potential Cdc28p substrate; contains a Phox homology (PX) domain and specifically binds phosphatidylinositol 3-phosphate (PtdIns-3-P); Ykr078wp [Saccharomyces ce [NCBI NR]
  • gi|549636|sp|P36158.1|YK58_YEAST RecName: Full=Uncharacterized protein YKR078W [NCBI NR]
  • pir||S38155 hypothetical protein YKR078w - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|486555|emb|CAA82157.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • Uncharacterized protein YKR078W OS=Saccharomyces cerevisiae GN=YKR078W PE=1 SV=1 [Swiss-Prot]
  • Protein of unknown function localised to cytoplasm [mips]
  • Cytoplasmic protein of unknown function, has similarity to Vps5p; potential Cdc28p substrate; contains a Phox homology (PX) domain and specifically binds phosphatidylinositol 3-phosphate (PtdIns-3-P) [SGD]
  • YKR078W, Chr XI from 584588-586345 [yeast_orfs2]
  • Chr XI from 584588-586345 [yeastorf3.fasta]
  • (P36158) Hypothetical 68.3 kDa protein in SIS2-MTD1 intergenic region [4932.FASTACCERV.txt]
  • YKR078W SGDID:S0001786, Chr XI from 584594-586351, Uncharacterized ORF [yeastflysequest.fasta]
  • Cytoplasmic protein of unknown function, has similarity to Vps5p; potential Cdc28p substrate [Saccharomyces cerevisiae]gi|486555|emb|CAA82157.1| unnamed protein product [Saccharomyces cerevisiae]gi|539277|pir||S38155 hypothetical protein YKR078w - yeast [nrdb_11152004_Chlamydomonas]
  • YKR078W SGDID:S000001786, Chr XI from 584594-586351, Uncharacterized ORF, "Cytoplasmic protein of unknown function, has similarity to Vps5p; potential Cdc28p substrate" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • YKR078W SGDID:S000001786, Chr XI from 584594-586351, Verified ORF, "Cytoplasmic protein of unknown function, has similarity to Vps5p; potential Cdc28p substrate; contains a Phox homology (PX) domain and specifically binds phosphatidylinositol 3-phosphate [yeast-contam.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Hypothetical 68.3 kDa protein in SIS2-MTD1 intergenic region [nr-271106-contam.fasta]
  • Cytoplasmic protein of unknown function, has similarity to Vps5p; potential Cdc28p substrate; contains a Phox homology (PX) domain and specifically binds phosphatidylinositol 3-phosphate (PtdIns-3-P); Ykr078wp [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • YKR078W SGDID:S000001786, Chr XI from 584594-586351, Verified ORF, "Cytoplasmic protein of unknown function, has similarity to Vps5p; potential Cdc28p substrate; contains a Phox homology (PX) domain and specifically binds phosphatidylinositol 3-phosphate (PtdIns-3-P)" [yeast-bovrabprots.fasta]
  • [chemostatdb.fasta]
  • Uncharacterized protein YKR078W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YKR078W PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • YKR078W SGDID:S000001786, Chr XI from 584952-586709, Genome Release 64-1-1, Verified ORF, "Cytoplasmic protein of unknown function, has similarity to Vps5p; potential Cdc28p substrate; contains a Phox homology (PX) domain and specifically binds phosphatidylinositol 3-phosphate (PtdIns-3-P)" [yeast-030211-contam.fasta]
  • YKR078W SGDID:S000001786, Chr XI from 584952-586709, Genome Release 64-2-1, Verified ORF, "Cytoplasmic protein of unknown function; potential Cdc28p substrate; contains a Phox homology (PX) domain and specifically binds phosphatidylinositol 3-phosphate (PtdIns-3-P); YKR078W has a paralog, VPS5, that arose from the whole genome duplication" [20141208_orf_trans.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 585 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: protein transport [ISSLink to PubMed article]
    Molecular Function: protein transporter activity [ISSLink to PubMed article]
    phosphatidylinositol-3-phosphate binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENDKASHAS PSIGVNEFVV QGEISIDDSE RSVKSVSVSI SDDEDSKTDV QDNMATPSTR  60
   61 SKFQTDLAID NRLLEKDPKY KKLFTEKRRR RRPESCINLM TKGKGTGQKD NINDQIFSLR 120
  121 ILPGSDLNSL KDSLWIIKIS TQPDVEKTIA RAFSDFYWLY HQLQNNHWGK TIPPPTRSNI 180
  181 LVEKDEFAIN HLFMIRNNEK YDPIFNFKPE YIISLQLMAM IKHIFNDKVL RLDSNFIDFI 240
  241 SWDDDLPESL QIVVDDSTFT GDKILMTSSQ FRELKEFHKQ SKKVESITNS HASLIPVTEL 300
  301 TEIYISPTKL FSRKDYQRLF QPQSTDNTFN NNDPLIQEWI PKSKTLFTSL SFGSSAPTYQ 360
  361 EASTEIQACH DWVSISKEQW KQLLYHVLQY IVDEAVKVNS VINEFTECLK QISLDEVIRA 420
  421 NSELFLKFSK LNESFLKKFK GASRQDILKL IILFDENVRF CESFESILNQ RLKLGKILSI 480
  481 IEVDLDKKKN FLDKLSPGNN NSNNEDLKIR TAEDEYRIVL KRYNRVKQSW EKIMEDILNE 540
  541 RKEFEKREAA EVNSCLKSIR DLNMDEKKHY LQLWQDFVPD EHISQ

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) AIM18 PLM2 SPO75 YKR078W

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen YKR078W RFC2 2 Unpublished Fields Lab Data
    View Screen YKR078W BIT61 1 Unpublished Fields Lab Data
    View Screen YKR078W SPT10 1 Unpublished Fields Lab Data
    View Screen YKR078W ATG16 1 Unpublished Fields Lab Data
    View Screen YKR078W PET494 1 Unpublished Fields Lab Data
    View Screen SAS3 YKR078W 1 Unpublished Fields Lab Data
    View Screen HXK2 YKR078W 1 Unpublished Fields Lab Data
    View Screen YKR078W CDC36 1 Unpublished Fields Lab Data
    View Screen YKR078W NRP1 1 Unpublished Fields Lab Data
    View Screen YKR078W YDR048C 1 Unpublished Fields Lab Data
    View Screen YKR078W VPS45 1 Unpublished Fields Lab Data
    View Screen YKR078W PAN1 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data YKR078W Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..253] ab initio 9.92 No description for 1h6hA was found.
    2 View Details [254..355] MSA 1.058993 View MSA. No confident structure predictions are available.
    3 View Details [356..585] ab initio 8.82 No description for 1i84S was found.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle