Protein Overview: SET6

General Information:
Name(s) found:	SET6 / YPL165C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|74583857\|sp\|Q12529.1\|SET6_YEAST RecName: Full=Potential protein lysine methyltransferase SET6; AltName: Full=SET domain-containing protein 6 [NCBI NR] gi\|6325092\|ref\|NP_015160.1\| Protein of unknown function; deletion heterozygote is sensitive to compounds that target ergosterol biosynthesis, may be involved in compound availability; Set6p [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S65176 hypothetical protein YPL165c - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1403544\|emb\|CAA65556.1\| P2545 protein [Saccharomyces cerevisiae] [NCBI NR] gi\|1370351\|emb\|CAA97872.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] Potential protein lysine methyltransferase SET6 OS=Saccharomyces cerevisiae GN=SET6 PE=2 SV=1 [Swiss-Prot] SET6 SET domain-containing protein [mips] SET domain protein of unknown function; deletion heterozygote is sensitive to compounds that target ergosterol biosynthesis, may be involved in compound availability [SGD] >Q12529 (Q12529) ORF YPL165C [4932.FASTACCERV.txt] Chr XVI from 239076-237955, reverse complement [hmr_yeast5_DM3-1_pombe.fasta] Chr XVI from 237955-239076, reverse complement [yeastorf3.fasta] YPL165C, Chr XVI from 237955-239076, reverse complement [yeast_orfs2] SET6 SGDID:S0006086, Chr XVI from 239076-237955, reverse complement, Verified ORF [yeastflysequest.fasta] Set6p [Saccharomyces cerevisiae]gi\|1403544\|emb\|CAA65556.1\| P2545 protein [Saccharomyces cerevisiae]gi\|1370351\|emb\|CAA97872.1\| unnamed protein product [Saccharomyces cerevisiae]gi\|2132215\|pir\|\|S65176 hypothetical protein YPL165c - yeast (Saccharomyces c [nrdb_11152004_Chlamydomonas] (Q12529) ORF YPL165c (P2545 protein) [cerv4932.FASTAC] SET6 SGDID:S000006086, Chr XVI from 239076-237955, reverse complement, Verified ORF, "Protein of unknown function; deletion heterozygote is sensitive to compounds that target ergosterol biosynthesis, may be involved in compound availability" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] SET6 SGDID:S000006086, Chr XVI from 239076-237955, reverse complement, Verified ORF, "SET domain protein of unknown function; deletion heterozygote is sensitive to compounds that target ergosterol biosynthesis, may be involved in compound availability" [yeast-200209-contam.fasta] P2545 protein [Saccharomyces cerevisiae] [nr-271106-contam.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Protein of unknown function; deletion heterozygote is sensitive to compounds that target ergosterol biosynthesis, may be involved in compound availability; Set6p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] Potential protein lysine methyltransferase SET6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SET6 PE=2 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] SET6 SGDID:S000006086, Chr XVI from 239077-237956, Genome Release 64-1-1, reverse complement, Verified ORF, "SET domain protein of unknown function; deletion heterozygote is sensitive to compounds that target ergosterol biosynthesis, may be involved in compound availability" [yeast-030211-contam.fasta] Potential protein lysine methyltransferase SET6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SET6 PE=3 SV=1 [YEAST.fasta.20131015] SET6 SGDID:S000006086, Chr XVI from 239077-237956, Genome Release 64-2-1, reverse complement, Verified ORF, "SET domain protein of unknown function; deletion heterozygote is sensitive to compounds that target ergosterol biosynthesis, may be involved in compound availability" [20141208_orf_trans.fasta] YPL165C SGDID:S000006086, Chr XVI from 239077-237956, Genome Release 64-1-1, reverse complement, Verified ORF, "SET domain protein of unknown function; deletion heterozygote is sensitive to compounds that target ergosterol biosynthesis, may be involved in compound availability" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	373 amino acids
Gene Ontology:
Cellular Component:	cellular_component [ND]
Biological Process:	biological_process [ND]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTIDGDVHEI SPFFQVRQTK WGGRACFSNG NIPKGTTVLQ VSNFTGTSIS YEFRKEVCHN  60
   61 CFAYANAKTM KYKLNYDYLR DLVCNAHYQI NPKKFLGAGL WFCSEHCRTS YLQIPNIIEL 120
  121 IECYEILLHH FPSMLKRYNY TSEQEEKLNS ILISENVIQS SWDEIESKWI PRINNMKSAK 180
  181 RINQLPPTCE DEYCCIRFVC ESLFNLKYMD PQCITYRAFN MLQSNELSKI SKFPVLLHFQ 240
  241 KLVFQTLYIL LPSHLHRMLS IPLLRHILGT EYGNAFGLWQ EGEASDSREY FGYWVFPEAS 300
  301 YFNHSCNPNI TKYRKGNSML FTMNRDIKKD EQICIDYSGV LDLPTVKRRA FLADSWFFDC 360
  361 ACERCKSELQ SVH

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	LIA1	SET6	1	Unpublished Fields Lab Data
View Screen	CCE1	SET6	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..84]	MSA	2.196997	View MSA. No confident structure predictions are available.
2	View Details	[85..373]	PSI-BLAST	20.522879	Dim-5

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2