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Protein Overview: AP1S1

General Information:
Name(s) found: AP1S1 [HGNC (HUGO)]
Description(s) found:
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  • gi|48428719|sp|P61966.1|AP1S1_HUMAN RecName: Full=AP-1 complex subunit sigma-1A; AltName: Full=Adapter-related protein complex 1 sigma-1A subunit; AltName: Full=Adaptor protein complex AP-1 sigma-1A subunit; AltName: Full=Sigma-adaptin 1A; AltName: Full=S [NCBI NR]
  • gi|4557471|ref|NP_001274.1| adaptor-related protein complex 1, sigma 1 subunit [Homo sapiens] [NCBI NR]
  • gi|3641678|dbj|BAA33391.1| sigma1A subunit of AP-1 clathrin adaptor complex [Homo sapiens] [NCBI NR]
  • gi|189053279|dbj|BAG35085.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|119570585|gb|EAW50200.1| adaptor-related protein complex 1, sigma 1 subunit, isoform CRA_b [Homo sapiens] [NCBI NR]
  • gi|119570584|gb|EAW50199.1| adaptor-related protein complex 1, sigma 1 subunit, isoform CRA_b [Homo sapiens] [NCBI NR]
  • adaptor-related protein complex 1, sigma 1 subunit [HGNC (HUGO)]
  • AP-1 complex subunit sigma-1A OS=Homo sapiens GN=AP1S1 PE=1 SV=1 [Swiss-Prot]
  • (P61966) Adapter-related protein complex 1 sigma 1A subunit (Sigma-adaptin 1A) (Adaptor protein complex AP-1 sigma-1A subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1A subunit) (Clathrin assembly protein complex 1 sigma-1A small chain) (Clathri [Swiss-Prot]
  • Splice isoform 1 of Q00382 [hmr_yeast5_DM3-1_pombe.fasta]
  • adaptor-related protein complex 1, sigma 1 subunit isoform 1; clathrin-associated/assembly/adaptor protein, small 1 (19kD); AP1S1adaptor-related protein complex 1, sigma 1 subunit [HMR_022704.fasta]
  • similar to clathrin-associated protein 19 - mouse [Rattus norvegicus]gi|30931131|gb|AAH52692.1| Ap1s1 protein [Mus musculus]gi|6671559|ref|NP_031483.1| adaptor protein complex AP-1, sigma 1 [Mus musculus]gi|4557471|ref|NP_001274.1| adaptor-related prot [nrdb_11152004_Chlamydomonas]
  • Adapter-related protein complex 1 sigma 1A subunit (Sigma-adaptin 1A) (Adaptor protein complex AP-1 sigma-1A subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1A subunit) (Clathrin assembly protein complex 1 sigma-1A small chain) (Clathrin coat assembly prote [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 1 of AP-1 complex subunit sigma-1A [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_001283) adaptor-related protein complex 1, sigma 1 subunit isoform 1; clathrin-associated/assembly/adaptor protein, small 1 (19kD); AP1S1adaptor-related protein complex 1, sigma 1 subunit [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • adaptor-related protein complex 1, sigma 1 subunit isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 1 of Adapter-related protein complex 1 sigma 1A subunit [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta]
  • adaptor-related protein complex 1, sigma 1 subunit isoform 1; clathrin-associated/assembly/adaptor protein, small 1 (19kD); AP1S1adaptor-related protein complex 1, sigma 1 subunit [Homo sapiens] [HumanGallus06162005.fasta]
  • AP-1 complex subunit sigma-1A (Adapter-related protein complex 1 sigma-1A subunit) (Adaptor protein complex AP-1 sigma-1A subunit) (Sigma-adaptin 1A) (Sigma1A-adaptin) (Golgi adaptor HA1/AP1 adaptin sigma-1A subunit) (HA1 19 kDa subunit) (Clathrin assembl [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • adaptor-related protein complex 1, sigma 1 subunit [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • adaptor-related protein complex 1, sigma 1 subunit, isoform CRA_b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • sigma1A subunit of AP-1 clathrin adaptor complex [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Isoform 1 of AP-1 complex subunit sigma-1A [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 SPLICE ISOFORM 1 OF ADAPTER-RELATED PROTEIN COMPLEX 1 SIGMA 1A SUBUNIT [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=AP1S1 Isoform 1 of AP-1 complex subunit sigma-1A [human-ipi-250309-contam.fasta]
  • AP-1 complex subunit sigma-1A (Adapter-related protein complex 1 sigma-1A subunit) (Sigma-adaptin 1A) (Adaptor protein complex AP-1 sigma-1A subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1A subunit) (Clathrin assembly protein complex 1 sigma-1A small chai [nr-271106-contam.fasta]
  • IPI:IPI00152898.1|SWISS-PROT:P61966-1|TREMBL:B2R5D8|ENSEMBL:ENSP00000336666;ENSP00000410780|REFSEQ:NP_001274|H-INV:HIT000271400|VEGA:OTTHUMP00000211467;OTTHUMP00000211468 Tax_Id=9606 Gene_Symbol=AP1S1 Isoform 1 of AP-1 complex subunit sigma-1A [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=AP1S1 Isoform 1 of AP-1 complex subunit sigma-1A ENSG00000106367 IPI00152898 IPI00100559 [drosphohumanreversed.fasta]
  • P61966;B2R5D8;P82267;Q00382;Q53YA7;Q9BTN4;Q9UDW9; RecName: Full=AP-1 complex subunit sigma-1A; AltName: Full=Adapter-related protein complex 1 sigma-1A subunit; AltName: Full=Adaptor protein complex AP-1 sigma-1A subunit; AltName: Full=Sigma-adaptin 1A; AltName: Full=Sigma1A-adaptin; AltName: Full=Golgi adaptor HA1/AP1 adaptin sigma-1A subunit; AltName: Full=HA1 19 kDa subunit; AltName: Full=Clathrin assembly protein complex 1 sigma-1A small chain; AltName: Full=Clathrin coat assembly protein AP19; AltName: Full=Sigma 1a subunit of AP-1 clathrin; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1 of AP-1 complex subunit sigma-1A OS=Homo sapiens GN=AP1S1 [011711_HMR.fasta]
  • IPI:IPI00152898.1|SWISS-PROT:P61966-1|ENSEMBL:ENSP00000336666;ENSP00000410780|REFSEQ:NP_001274|H-INV:HIT000271400|VEGA:OTTHUMP00000211467;OTTHUMP00000211468 Tax_Id=9606 Gene_Symbol=AP1S1 Isoform 1 of AP-1 complex subunit sigma-1A [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=AP1S1 Synonyms=AP19|CLAPS1|FLJ92436|SIGMA1A|WUGSC:H_DJ0747G18.2 AP-1 complex subunit sigma-1A [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • AP-1 complex subunit sigma-1A GN=AP1S1 [Doctor+uniprot-HUMAN-120911.fasta]
  • Adaptor-related protein complex 1, sigma 1 subunit, isoform CRA_b OS=Homo sapiens GN=AP1S1 PE=4 SV=1 [uniprot-human-031015-contam.fasta]
    • Organism: Homo sapiens
    Length: 158 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMRFMLLFSR QGKLRLQKWY LATSDKERKK MVRELMQVVL ARKPKMCSFL EWRDLKVVYK  60
   61 RYASLYFCCA IEGQDNELIT LELIHRYVEL LDKYFGSVCE LDIIFNFEKA YFILDEFLMG 120
  121 GDVQDTSKKS VLKAIEQADL LQEEDESPRS VLEEMGLA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..158] PSI-BLAST 44.69897 AP1 clathrin adaptor core


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle