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Protein Overview: PAFAH1B2

General Information:
Name(s) found: PAFAH1B2 [HGNC (HUGO)]
Description(s) found:
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  • pir||JC5409 platelet-activating factor acetylhydrolase (EC 3.-.-.-) Ib beta chain - human [NCBI NR]
  • gi|67463792|pdb|1VYH|R Chain R, Paf-Ah Holoenzyme: Lis1ALFA2 [NCBI NR]
  • gi|67463791|pdb|1VYH|Q Chain Q, Paf-Ah Holoenzyme: Lis1ALFA2 [NCBI NR]
  • gi|67463788|pdb|1VYH|N Chain N, Paf-Ah Holoenzyme: Lis1ALFA2 [NCBI NR]
  • gi|67463787|pdb|1VYH|M Chain M, Paf-Ah Holoenzyme: Lis1ALFA2 [NCBI NR]
  • gi|67463784|pdb|1VYH|J Chain J, Paf-Ah Holoenzyme: Lis1ALFA2 [NCBI NR]
  • gi|67463783|pdb|1VYH|I Chain I, Paf-Ah Holoenzyme: Lis1ALFA2 [NCBI NR]
  • gi|67463780|pdb|1VYH|F Chain F, Paf-Ah Holoenzyme: Lis1ALFA2 [NCBI NR]
  • gi|67463779|pdb|1VYH|E Chain E, Paf-Ah Holoenzyme: Lis1ALFA2 [NCBI NR]
  • gi|67463776|pdb|1VYH|B Chain B, Paf-Ah Holoenzyme: Lis1ALFA2 [NCBI NR]
  • gi|67463775|pdb|1VYH|A Chain A, Paf-Ah Holoenzyme: Lis1ALFA2 [NCBI NR]
  • gi|55977294|sp|P68402.1|PA1B2_HUMAN RecName: Full=Platelet-activating factor acetylhydrolase IB subunit beta; AltName: Full=PAF acetylhydrolase 30 kDa subunit; Short=PAF-AH 30 kDa subunit; AltName: Full=PAF-AH subunit beta; AltName: Full=PAFAH subunit bet [NCBI NR]
  • gi|48145589|emb|CAG33017.1| PAFAH1B2 [Homo sapiens] [NCBI NR]
  • gi|4505585|ref|NP_002563.1| platelet-activating factor acetylhydrolase, isoform Ib, beta subunit [Homo sapiens] [NCBI NR]
  • gi|2081614|dbj|BAA19917.1| acetylhydrolase IB beta-subunit [Homo sapiens] [NCBI NR]
  • gi|17939632|gb|AAH19301.1| Platelet-activating factor acetylhydrolase, isoform Ib, beta subunit 30kDa [Homo sapiens] [NCBI NR]
  • gi|167887649|gb|ACA06040.1| platelet-activating factor acetylhydrolase IB subunit beta [Homo sapiens] [NCBI NR]
  • gi|158259407|dbj|BAF85662.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|12653259|gb|AAH00398.1| Platelet-activating factor acetylhydrolase, isoform Ib, beta subunit 30kDa [Homo sapiens] [NCBI NR]
  • gi|119587686|gb|EAW67282.1| platelet-activating factor acetylhydrolase, isoform Ib, beta subunit 30kDa, isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119587685|gb|EAW67281.1| platelet-activating factor acetylhydrolase, isoform Ib, beta subunit 30kDa, isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|114228437|gb|ABI58230.1| intracellular platelet-activating factor acetylhydrolase alpha 2 subunit [Homo sapiens] [NCBI NR]
  • platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) [HGNC (HUGO)]
  • (Q29459) Platelet-activating factor acetylhydrolase IB beta subunit (EC 3.1.1.47) (PAF acetylhydrolase 30 kDa subunit) (PAF-AH 30 kDa subunit) (PAF-AH beta subunit) (PAFAH beta subunit) [Swiss-Prot]
  • Platelet-activating factor acetylhydrolase IB subunit beta OS=Homo sapiens GN=PAFAH1B2 PE=1 SV=1 [Swiss-Prot]
  • Platelet-activating factor acetylhydrolase IB beta subunit [hmr_yeast5_DM3-1_pombe.fasta]
  • platelet-activating factor acetylhydrolase, isoform Ib, beta subunit 30kDa; platelet-activating factor acetylhydrolase, isoform Ib, beta subunit (30kD); Platelet-activating factor acetylhydrolase, isoform Ib, beta subunit [HMR_022704.fasta]
  • platelet-activating factor acetylhydrolase, isoform Ib, beta subunit 30kDa; Platelet-activating factor acetylhydrolase, isoform Ib, beta subunit; platelet-activating factor acetylhydrolase, isoform Ib, beta subunit (30kD) [Human2242005.fasta]
  • platelet-activating factor acetylhydrolase, isoform Ib, beta subunit 30kDa [Homo sapiens]gi|27807193|ref|NP_777089.1| platelet-activating factor acetylhydrolase, isoform Ib, beta subunit (30kD) [Bos taurus]gi|17939632|gb|AAH19301.1| Platelet-activating [nrdb_11152004_Chlamydomonas]
  • Platelet-activating factor acetylhydrolase IB beta subunit (PAF acetylhydrolase 30 kDa subunit) (PAF-AH 30 kDa subunit) (PAF-AH beta subunit) (PAFAH beta subunit) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Platelet-activating factor acetylhydrolase IB beta subunit [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_002572) platelet-activating factor acetylhydrolase, isoform Ib, beta subunit (30kD); Platelet-activating factor acetylhydrolase, isoform Ib, beta subunit [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • platelet-activating factor acetylhydrolase, isoform Ib, beta subunit 30kDa [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • platelet-activating factor acetylhydrolase, isoform Ib, beta subunit 30kDa; Platelet-activating factor acetylhydrolase, isoform Ib, beta subunit; platelet-activating factor acetylhydrolase, isoform Ib, beta subunit (30kD) [Homo sapiens] [HumanGallus06162005.fasta]
  • platelet-activating factor acetylhydrolase, isoform Ib, beta subunit 30kDa; platelet-activating factor acetylhydrolase, isoform Ib, beta subunit (30kD); Platelet-activating factor acetylhydrolase, isoform Ib, beta subunit [Homo sapiens] [human-NCBI-042104-rand.fasta]
  • Chain R, Paf-Ah Holoenzyme: Lis1ALFA2 [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Chain Q, Paf-Ah Holoenzyme: Lis1ALFA2 [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Chain N, Paf-Ah Holoenzyme: Lis1ALFA2 [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Chain M, Paf-Ah Holoenzyme: Lis1ALFA2 [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Chain J, Paf-Ah Holoenzyme: Lis1ALFA2 [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Chain I, Paf-Ah Holoenzyme: Lis1ALFA2 [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Chain F, Paf-Ah Holoenzyme: Lis1ALFA2 [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Chain E, Paf-Ah Holoenzyme: Lis1ALFA2 [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Chain B, Paf-Ah Holoenzyme: Lis1ALFA2 [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Chain A, Paf-Ah Holoenzyme: Lis1ALFA2 [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Platelet-activating factor acetylhydrolase IB subunit beta (PAF acetylhydrolase 30 kDa subunit) (PAF-AH 30 kDa subunit) (PAF-AH subunit beta) (PAFAH subunit beta) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • platelet-activating factor acetylhydrolase IB subunit beta [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • intracellular platelet-activating factor acetylhydrolase alpha 2 subunit [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • platelet-activating factor acetylhydrolase, isoform Ib, beta subunit 30kDa, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Platelet-activating factor acetylhydrolase, isoform Ib, beta subunit 30kDa [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • PAFAH1B2 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • acetylhydrolase IB beta-subunit [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Platelet-activating factor acetylhydrolase IB subunit beta [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB BETA SUBUNIT [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=PAFAH1B2 Platelet-activating factor acetylhydrolase IB subunit beta [human-ipi-250309-contam.fasta]
  • platelet-activating factor acetylhydrolase, isoform Ib, beta subunit [Homo sapiens] [NCBI-RefSeq_human_na_07-13-2009_con_reversed.fasta]
  • platelet-activating factor acetylhydrolase, isoform Ib, subunit 2 [Homo sapiens] [NCBI-RefSeq_human_na_10-19-2009_con_reversed.fasta]
  • IPI:IPI00026546.1|SWISS-PROT:P68402|TREMBL:Q6IBR6|ENSEMBL:ENSP00000304006|REFSEQ:NP_002563|H-INV:HIT000282479 Tax_Id=9606 Gene_Symbol=PAFAH1B2 Platelet-activating factor acetylhydrolase IB subunit beta [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=PAFAH1B2 Platelet-activating factor acetylhydrolase IB subunit beta ENSG00000168092 IPI00026546 IPI00815864 [drosphohumanreversed.fasta]
  • P68402;O00687;Q29459; RecName: Full=Platelet-activating factor acetylhydrolase IB subunit beta; AltName: Full=PAF acetylhydrolase 30 kDa subunit; AltName: Full=PAF-AH subunit beta; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Platelet-activating factor acetylhydrolase IB subunit beta OS=Homo sapiens GN=PAFAH1B2 [011711_HMR.fasta]
  • GeneSymbol=PAFAH1B2 Synonyms=- platelet-activating factor acetylhydrolase IB subunit beta isoform a [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00026546.1|SWISS-PROT:P68402|TREMBL:Q6IBR6|ENSEMBL:ENSP00000435289|REFSEQ:NP_002563|H-INV:HIT000282479|VEGA:OTTHUMP00000234977 Tax_Id=9606 Gene_Symbol=PAFAH1B2 Platelet-activating factor acetylhydrolase IB subunit beta [ipi.HUMAN.20110912.fasta]
  • Platelet-activating factor acetylhydrolase IB subunit beta GN=PAFAH1B2 [Doctor+uniprot-HUMAN-120911.fasta]
  • Epididymis secretory protein Li 303 OS=Homo sapiens GN=HEL-S-303 PE=2 SV=1 [uniprot-human-031015-contam.fasta]
    • Organism: Homo sapiens
    Length: 229 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQGDSNPAA IPHAAEDIQG DDRWMSQHNR FVLDCKDKEP DVLFVGDSMV QLMQQYEIWR  60
   61 ELFSPLHALN FGIGGDTTRH VLWRLKNGEL ENIKPKVIVV WVGTNNHENT AEEVAGGIEA 120
  121 IVQLINTRQP QAKIIVLGLL PRGEKPNPLR QKNAKVNQLL KVSLPKLANV QLLDTDGGFV 180
  181 HSDGAISCHD MFDFLHLTGG GYAKICKPLH ELIMQLLEET PEEKQTTIA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..229] PSI-BLAST 60.0 Platelet-activating factor acetylhydrolase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.84091517928452 bayes_pls_golite062009
  • platelet-activating factor acetyltransferase activity
    		•  0.732293103277365 bayes_pls_golite062009
  • protein binding
    		•  0.564720396960066 bayes_pls_golite062009
  • hydrolase activity
    		•  0.45071330223777 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle