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Protein Overview: CPB1

General Information:
Name(s) found: CPB1 [HGNC (HUGO)]
Description(s) found:
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  • gi|54607080|ref|NP_001862.2| pancreatic carboxypeptidase B1 preproprotein [Homo sapiens] [NCBI NR]
  • gi|32880163|gb|AAP88912.1| carboxypeptidase B1 (tissue) [Homo sapiens] [NCBI NR]
  • gi|20532382|sp|P15086.4|CBPB1_HUMAN RecName: Full=Carboxypeptidase B; AltName: Full=Pancreas-specific protein; Short=PASP; Flags: Precursor [NCBI NR]
  • gi|15929839|gb|AAH15338.1| Carboxypeptidase B1 (tissue) [Homo sapiens] [NCBI NR]
  • gi|119599309|gb|EAW78903.1| carboxypeptidase B1 (tissue), isoform CRA_a [Homo sapiens] [NCBI NR]
  • carboxypeptidase B1 (tissue) [HGNC (HUGO)]
  • (P15086) Carboxypeptidase B precursor (EC 3.4.17.2) (Pancreas-specific protein) (PASP) [Swiss-Prot]
  • Carboxypeptidase B OS=Homo sapiens GN=CPB1 PE=1 SV=4 [Swiss-Prot]
  • Carboxypeptidase B precursor [hmr_yeast5_DM3-1_pombe.fasta]
  • pancreatic carboxypeptidase B1 preproprotein [Homo sapiens]gi|32880163|gb|AAP88912.1| carboxypeptidase B1 (tissue) [Homo sapiens]gi|15929839|gb|AAH15338.1| Pancreatic carboxypeptidase B1, precursor [Homo sapiens]gi|20532382|sp|P15086|CBPB_HUMAN Carboxy [nrdb_11152004_Chlamydomonas]
  • Carboxypeptidase B precursor (Pancreas-specific protein) (PASP) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Carboxypeptidase B precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • pancreatic carboxypeptidase B1 preproprotein [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • carboxypeptidase B1 (tissue), isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Carboxypeptidase B1 (tissue) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • carboxypeptidase B1 (tissue) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 CARBOXYPEPTIDASE B PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=CPB1 Carboxypeptidase B [human-ipi-250309-contam.fasta]
  • IPI:IPI00009826.2|SWISS-PROT:P15086|TREMBL:Q53XJ0;Q68DJ8|ENSEMBL:ENSP00000282957|REFSEQ:NP_001862|H-INV:HIT000303003|VEGA:OTTHUMP00000173158 Tax_Id=9606 Gene_Symbol=CPB1 Carboxypeptidase B [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=CPB1 Carboxypeptidase B precursor ENSG00000153002 IPI00009826 IPI00796280 IPI00795954 IPI00795311 IPI00794669 IPI00794066 IPI00797836 IPI00797173 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=CPB1 Carboxypeptidase B precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • carboxypeptidase B preproprotein [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • P15086;O60834;Q53XJ0;Q96BQ8; RecName: Full=Carboxypeptidase B; AltName: Full=Pancreas-specific protein; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Carboxypeptidase B OS=Homo sapiens GN=CPB1 [011711_HMR.fasta]
  • IPI:IPI00009826.2|SWISS-PROT:P15086|TREMBL:Q68DJ8|ENSEMBL:ENSP00000282957;ENSP00000417222|REFSEQ:NP_001862|H-INV:HIT000303003|VEGA:OTTHUMP00000173158 Tax_Id=9606 Gene_Symbol=CPB1 Carboxypeptidase B [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=CPB1 Synonyms=CPB|DKFZp779K1333|PASP|PCPB carboxypeptidase B preproprotein [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00009826.2|SWISS-PROT:P15086|TREMBL:Q68DJ8|ENSEMBL:ENSP00000282957;ENSP00000417222|REFSEQ:NP_001862|H-INV:HIT000303003|VEGA:OTTHUMP00000215657 Tax_Id=9606 Gene_Symbol=CPB1 Carboxypeptidase B [ipi.HUMAN.20110912.fasta]
  • Carboxypeptidase B GN=CPB1 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 417 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLALLVLVTV ALASAHHGGE HFEGEKVFRV NVEDENHINI IRELASTTQI DFWKPDSVTQ  60
   61 IKPHSTVDFR VKAEDTVTVE NVLKQNELQY KVLISNLRNV VEAQFDSRVR ATGHSYEKYN 120
  121 KWETIEAWTQ QVATENPALI SRSVIGTTFE GRAIYLLKVG KAGQNKPAIF MDCGFHAREW 180
  181 ISPAFCQWFV REAVRTYGRE IQVTELLDKL DFYVLPVLNI DGYIYTWTKS RFWRKTRSTH 240
  241 TGSSCIGTDP NRNFDAGWCE IGASRNPCDE TYCGPAAESE KETKALADFI RNKLSSIKAY 300
  301 LTIHSYSQMM IYPYSYAYKL GENNAELNAL AKATVKELAS LHGTKYTYGP GATTIYPAAG 360
  361 GSDDWAYDQG IRYSFTFELR DTGRYGFLLP ESQIRATCEE TFLAIKYVAS YVLEHLY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..417] PSI-BLAST 133.0 Carboxypeptidase B; Procarboxypeptidase B

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  4.786910294594 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  4.40766568731738 bayes_pls_golite062009
  • hydrolase activity
    		•  4.23257784904124 bayes_pls_golite062009
  • exopeptidase activity
    		•  3.28577934113028 bayes_pls_golite062009
  • metallopeptidase activity
    		•  2.76103081380105 bayes_pls_golite062009
  • carboxypeptidase activity
    		•  2.63658263814587 bayes_pls_golite062009
  • metalloexopeptidase activity
    		•  1.76058821499096 bayes_pls_golite062009
  • metallocarboxypeptidase activity
    		•  1.56827526553175 bayes_pls_golite062009
  • catalytic activity
    		•  1.3989281287879 bayes_pls_golite062009
  • binding
    		•  1.13031326446259 bayes_pls_golite062009
  • endopeptidase activity
    		•  0.910234727191613 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
    		•  0.723243947871592 bayes_pls_golite062009
  • serine hydrolase activity
    		•  0.596149133958797 bayes_pls_golite062009
  • serine-type peptidase activity
    		•  0.578572340123331 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.454707207494165 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.273337363793137 bayes_pls_golite062009
  • DNA binding
    		•  0.115087846898245 bayes_pls_golite062009
  • aminopeptidase activity
    		•  0.0966237570696103 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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