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Protein Overview: VPS16

General Information:
Name(s) found: VPS16 [HGNC (HUGO)]
Description(s) found:
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  • gi|23396927|sp|Q9H269.2|VPS16_HUMAN RecName: Full=Vacuolar protein sorting-associated protein 16 homolog; Short=hVPS16 [NCBI NR]
  • gi|17978479|ref|NP_072097.2| vacuolar protein sorting 16 isoform 1 [Homo sapiens] [NCBI NR]
  • gi|12140290|emb|CAC21465.1| vacuolar protein sorting 16 homolog (S. cerevisiae) [Homo sapiens] [NCBI NR]
  • gi|119630971|gb|EAX10566.1| hCG2039972, isoform CRA_c [Homo sapiens] [NCBI NR]
  • vacuolar protein sorting 16 homolog (S. cerevisiae) [HGNC (HUGO)]
  • Vacuolar protein sorting-associated protein 16 homolog OS=Homo sapiens GN=VPS16 PE=1 SV=2 [Swiss-Prot]
  • (Q9H269) Vacuolar protein sorting 16 (hVPS16) [Swiss-Prot]
  • Splice isoform 1 of Q9H269 [hmr_yeast5_DM3-1_pombe.fasta]
  • vacuolar protein sorting 16 isoform 1; vacuolar protein sorting protein 16 [HMR_022704.fasta]
  • vacuolar protein sorting 16 isoform 1; vacuolar protein sorting protein 16; vacuolar protein sorting 16 (yeast homolog) [071204_hmrz_cont.fasta]
  • vacuolar protein sorting 16 isoform 1 [Homo sapiens]gi|12140290|emb|CAC21465.1| bA12M19.2.1 (vacuolar protein sorting protein 16 (VPS16)) [Homo sapiens]gi|23396927|sp|Q9H269|VP16_HUMAN Vacuolar protein sorting 16 (hVPS16) [nrdb_11152004_Chlamydomonas]
  • Vacuolar protein sorting 16 (hVPS16) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 1 of Vacuolar protein sorting 16 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_022575) vacuolar protein sorting 16 (yeast), isoform 1; vacuolar protein sorting protein 16 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • vacuolar protein sorting 16 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • vacuolar protein sorting 16 isoform 1; vacuolar protein sorting protein 16; vacuolar protein sorting 16 (yeast homolog) [Homo sapiens] [HumanGallus06162005.fasta]
  • vacuolar protein sorting 16 isoform 1; vacuolar protein sorting protein 16 [Homo sapiens] [human-NCBI-042104-rand.fasta]
  • Vacuolar protein sorting-associated protein 16 homolog (hVPS16) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • vacuolar protein sorting 16 (yeast) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • hCG2039972, isoform CRA_c [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Isoform 1 of Vacuolar protein sorting-associated protein 16 [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 SPLICE ISOFORM 1 OF VACUOLAR PROTEIN SORTING 16 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=VPS16 Isoform 1 of Vacuolar protein sorting-associated protein 16 homolog [human-ipi-250309-contam.fasta]
  • Vacuolar protein sorting-associated protein 16 (hVPS16) [nr-271106-contam.fasta]
  • IPI:IPI00305438.3|SWISS-PROT:Q9H269-1|ENSEMBL:ENSP00000369810|REFSEQ:NP_072097|VEGA:OTTHUMP00000030047 Tax_Id=9606 Gene_Symbol=VPS16 Isoform 1 of Vacuolar protein sorting-associated protein 16 homolog [ipi.HUMAN.fasta.20090807]
  • Tax_Id=9606 Isoform 1 of Vacuolar protein sorting-associated protein 16 homolog [IPI_human_3.26.fasta]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=VPS16;PTPRA Isoform 1 of Vacuolar protein sorting-associated protein 16 homolog [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • vacuolar protein sorting-associated protein 16 homolog isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Q9H269;Q5JUB1;Q8WU31;Q96EE7;Q96N92;Q9H1Q4;Q9H1Q5; RecName: Full=Vacuolar protein sorting-associated protein 16 homolog; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1 of Vacuolar protein sorting-associated protein 16 homolog OS=Homo sapiens GN=VPS16 [011711_HMR.fasta]
  • GeneSymbol=VPS16 Synonyms=hVPS16 vacuolar protein sorting-associated protein 16 homolog isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • Vacuolar protein sorting-associated protein 16 homolog GN=VPS16 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 839 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDCYTANWNP LGDSAFYRKY ELYSMDWDLK EELRDCLVAA APYGGPIALL RNPWRKEKAA  60
   61 SVRPVLDIYS ASGMPLASLL WKSGPVVSLG WSAEEELLCV QEDGAVLVYG LHGDFRRHFS 120
  121 MGNEVLQNRV LDARIFHTEF GSGVAILTGA HRFTLSANVG DLKLRRMPEV PGLQSAPSCW 180
  181 TVLCQDRVAH ILLAVGPDLY LLDHAACSAV TPPGLAPGVS SFLQMAVSFT YRHLALFTDT 240
  241 GYIWMGTASL KEKLCEFNCN IRAPPKQMVW CSRPRSKERA VVVAWERRLM VVGDAPESIQ 300
  301 FVLDEDSYLV PELDGVRIFS RSTHEFLHEV PAASEEIFKI ASMAPGALLL EAQKEYEKES 360
  361 QKADEYLREI QELGQLTQAV QQCIEAAGHE HQPDMQKSLL RAASFGKCFL DRFPPDSFVH 420
  421 MCQDLRVLNA VRDYHIGIPL TYSQYKQLTI QVLLDRLVLR RLYPLAIQIC EYLRLPEVQG 480
  481 VSRILAHWAC YKVQQKDVSD EDVARAINQK LGDTPGVSYS DIAARAYGCG RTELAIKLLE 540
  541 YEPRSGEQVP LLLKMKRSKL ALSKAIESGD TDLVFTVLLH LKNELNRGDF FMTLRNQPMA 600
  601 LSLYRQFCKH QELETLKDLY NQDDNHQELG SFHIRASYAA EERIEGRVAA LQTAADAFYK 660
  661 AKNEFAAKAT EDQMRLLRLQ RRLEDELGGQ FLDLSLHDTV TTLILGGHNK RAEQLARDFR 720
  721 IPDKRLWWLK LTALADLEDW EELEKFSKSK KSPIGYLPFV EICMKQHNKY EAKKYASRVG 780
  781 PEQKVKALLL VGDVAQAADV AIEHRNEAEL SLVLSHCTGA TDGATADKIQ RARAQAQKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..611] FFAS03 3.15 Actin interacting protein 1
    2 View Details [612..689] deduced N/A No confident structure predictions are available.
    3 View Details [690..839] MSA 4.067993 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • actin binding
    		•  2.36802077000866 bayes_pls_golite062009
  • binding
    		•  2.23598589443994 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.1136449999874 bayes_pls_golite062009
  • transporter activity
    		•  1.23232041140488 bayes_pls_golite062009
  • protein binding
    		•  1.16796757764458 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.750051725890322 bayes_pls_golite062009
  • actin filament binding
    		•  0.680577261614999 bayes_pls_golite062009
  • hydrolase activity
    		•  0.346903609858078 bayes_pls_golite062009
  • tubulin binding
    		•  0.291956397524181 bayes_pls_golite062009
  • microtubule binding
    		•  0.213830210314093 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.0245411309982146 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle