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Protein Overview: TIMP3_MOUSE

General Information:
Name(s) found: TIMP3_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|8885522|dbj|BAA95094.2| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|74190773|dbj|BAE28178.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|730949|sp|P39876.1|TIMP3_MOUSE RecName: Full=Metalloproteinase inhibitor 3; AltName: Full=Tissue inhibitor of metalloproteinases 3; Short=TIMP-3; Flags: Precursor [NCBI NR]
  • gi|6755793|ref|NP_035725.1| tissue inhibitor of metalloproteinase 3 [Mus musculus] [NCBI NR]
  • pir||A53532 metalloproteinase inhibitor 3 precursor - mouse [NCBI NR]
  • gi|461361|emb|CAA83218.1| metalloproteinase-3 tissue inhibitor [Mus musculus] [NCBI NR]
  • gi|439882|gb|AAA40447.1| Timp-3 [NCBI NR]
  • gi|438811|gb|AAC37669.1| tissue inhibitor of metalloproteinases type 3 [NCBI NR]
  • gi|26350837|dbj|BAC39055.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|148689490|gb|EDL21437.1| tissue inhibitor of metalloproteinase 3, isoform CRA_a [Mus musculus] [NCBI NR]
  • gi|1167534|gb|AAA85860.1| tissue inhibitor of metalloproteinases-3 [NCBI NR]
  • Metalloproteinase inhibitor 3 OS=Mus musculus GN=Timp3 PE=1 SV=1 [Swiss-Prot]
  • (P39876) Metalloproteinase inhibitor 3 precursor (TIMP-3) (Tissue inhibitor of metalloproteinases-3) [Swiss-Prot]
  • Ensembl_locations(Chr-bp):10-85833186 Metalloproteinase inhibitor 3 precursor [hmr_yeast5_DM3-1_pombe.fasta]
  • tissue inhibitor of metalloproteinase 3 [HMR_022704-rand.fasta]
  • Metalloproteinase inhibitor 3 precursor [ipi.MOUSE.v3.06.fasta]
  • tissue inhibitor of metalloproteinase 3 [Mus musculus]gi|627944|pir||A53532 metalloproteinase inhibitor 3 precursor - mousegi|438811|gb|AAC37669.1| tissue inhibitor of metalloproteinases type 3gi|461361|emb|CAA83218.1| metalloproteinase-3 tissue inhibi [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10090 Metalloproteinase inhibitor 3 precursor [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta]
  • (NM_011595) tissue inhibitor of metalloproteinase 3 [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • tissue inhibitor of metalloproteinase 3 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • Metalloproteinase inhibitor 3 precursor (Tissue inhibitor of metalloproteinases 3) (TIMP-3) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • tissue inhibitor of metalloproteinase 3, isoform CRA_a [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • metalloproteinase-3 tissue inhibitor [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • tissue inhibitor of metalloproteinases type 3 [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • tissue inhibitor of metalloproteinases-3 [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Timp-3 [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 METALLOPROTEINASE INHIBITOR 3 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Timp3 Metalloproteinase inhibitor 3 [mouse-ipi-250309-contam.fasta]
  • tissue inhibitor of metalloproteinase 3 precursor [Mus musculus] [NCBI-RefSeq_mouse_na_09-14-2009_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Timp3 Metalloproteinase inhibitor 3 precursor [ipi.MOUSE_jw_12may08.contam.fasta]
  • Metalloproteinase inhibitor 3 precursor (TIMP-3) (Tissue inhibitor of metalloproteinases 3) [nr-271106-contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Timp3 Metalloproteinase inhibitor 3 precursor ENSMUSG00000020044 IPI00110370 [IPIxENS.MOUSE_plus_REVERSE.fasta]
  • metalloproteinase inhibitor 3 precursor [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta]
  • IPI:IPI00110370.1|SWISS-PROT:P39876|TREMBL:Q54AE5;Q6GXA7|ENSEMBL:ENSMUSP00000020234|REFSEQ:NP_035725|VEGA:OTTMUSP00000023387 Tax_Id=10090 Gene_Symbol=Timp3 Metalloproteinase inhibitor 3 [ipi.MOUSE.fasta.20090209]
  • Metalloproteinase inhibitor 3 OS=Mus musculus GN=Timp3 [011711_HMR.fasta]
  • Metalloproteinase inhibitor 3 OS=Mus musculus GN=Timp3 PE=2 SV=1 [UniProt_mouse_sprotvarsplic_11-08-2010_reversed.fasta]
  • sp|P39876|TIMP3_MOUSE Metalloproteinase inhibitor 3 OS=Mus musculus GN=Timp3 PE=2 SV=1 [uniprot.sptr.mouse.20130102]
  • tr|Q54AE5|Q54AE5_MOUSE Brain cDNA, clone MNCb-5810, similar to Mus musculus tissue inhibitor of metalloproteinase 3 (Timp3), mRNA OS=Mus musculus GN=Timp3 PE=2 SV=1 [uniprot.sptr.mouse.20130102]
  • Brain cDNA, clone MNCb-5810, similar to Mus musculus tissue inhibitor of metalloproteinase 3 (Timp3), mRNA OS=Mus musculus GN=Timp3 PE=2 SV=1 [mouse-uniprot-290313-contam.fasta]
  • Isoform of P39876, Brain cDNA, clone MNCb-5810, similar to Mus musculus tissue inhibitor of metalloproteinase 3 (Timp3), mRNA OS=Mus musculus GN=Timp3 PE=1 SV=1 [MOUSE.fasta.20160308]
    • Organism: Mus musculus
    Length: 211 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPWLGLVVL LSCWSLGHWG AEACTCSPSH PQDAFCNSDI VIRAKVVGKK LVKEGPFGTL  60
   61 VYTIKQMKMY RGFSKMPHVQ YIHTEASESL CGLKLEVNKY QYLLTGRVYE GKMYTGLCNF 120
  121 VERWDHLTLS QRKGLNYRYH LGCNCKIKSC YYLPCFVTSK NECLWTDMLS NFGYPGYQSK 180
  181 HYACIRQKGG YCSWYRGWAP PDKSISNATD P

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..211] PSI-BLAST 84.522879 HUMAN TISSUE INHIBITOR OF METALLOPROTEINASE-2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • metalloendopeptidase inhibitor activity
    		•  7.17434748400899 bayes_pls_golite062009
  • metalloenzyme regulator activity
    		•  7.17434748400899 bayes_pls_golite062009
  • metalloenzyme inhibitor activity
    		•  7.17434748400899 bayes_pls_golite062009
  • peptidase inhibitor activity
    		•  3.93668549411033 bayes_pls_golite062009
  • endopeptidase inhibitor activity
    		•  3.90361447859652 bayes_pls_golite062009
  • enzyme regulator activity
    		•  2.05189175806105 bayes_pls_golite062009
  • protein binding
    		•  2.04187591727985 bayes_pls_golite062009
  • receptor binding
    		•  1.79096938850925 bayes_pls_golite062009
  • cytokine activity
    		•  1.72828967672993 bayes_pls_golite062009
  • binding
    		•  1.57363735103063 bayes_pls_golite062009
  • enzyme inhibitor activity
    		•  1.54714635439345 bayes_pls_golite062009
  • G-protein-coupled receptor binding
    		•  0.6932827058439 bayes_pls_golite062009
  • chemokine activity
    		•  0.59253057522745 bayes_pls_golite062009
  • chemokine receptor binding
    		•  0.59253057522745 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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