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Protein Overview: GRAA_MOUSE

General Information:
Name(s) found: GRAA_MOUSE [Swiss-Prot]
Description(s) found:
Found 33 descriptions.
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  • Granzyme A OS=Mus musculus GN=Gzma PE=1 SV=2 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 260 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [IEA]
    Biological Process: cytolysis [IEA]
    apoptosis [IEA]
    proteolysis [IEA]
    Molecular Function: catalytic activity [IEA]
    serine-type peptidase activity [IDA]
    serine-type endopeptidase activity [IEA]
    peptidase activity [IEA]
    hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRNASGPRGP SLATLLFLLL IPEGGCERII GGDTVVPHSR PYMALLKLSS NTICAGALIE  60
   61 KNWVLTAAHC NVGKRSKFIL GAHSINKEPE QQILTVKKAF PYPCYDEYTR EGDLQLVRLK 120
  121 KKATVNRNVA ILHLPKKGDD VKPGTRCRVA GWGRFGNKSA PSETLREVNI TVIDRKICND 180
  181 EKHYNFHPVI GLNMICAGDL RGGKDSCNGD SGSPLLCDGI LRGITSFGGE KCGDRRWPGV 240
  241 YTFLSDKHLN WIKKIMKGSV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..260] PSI-BLAST 60.221849 Granzyme A

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  5.91209560688646 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  5.52773635813967 bayes_pls_golite062009
  • serine hydrolase activity
    		•  5.5105092190926 bayes_pls_golite062009
  • serine-type peptidase activity
    		•  5.49703869306079 bayes_pls_golite062009
  • serine-type endopeptidase activity
    		•  5.39623690248556 bayes_pls_golite062009
  • endopeptidase activity
    		•  5.32070018460528 bayes_pls_golite062009
  • hydrolase activity
    		•  4.40346950809697 bayes_pls_golite062009
  • fucose binding
    		•  3.5000591397073 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  2.01328116441763 bayes_pls_golite062009
  • calcium-dependent protein binding
    		•  1.96509840108953 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.73928761064649 bayes_pls_golite062009
  • receptor activity
    		•  1.63666837038605 bayes_pls_golite062009
  • DNA binding
    		•  1.61536775064425 bayes_pls_golite062009
  • heparin binding
    		•  1.48285358055737 bayes_pls_golite062009
  • thrombospondin receptor activity
    		•  1.44312413043539 bayes_pls_golite062009
  • catalytic activity
    		•  1.40927913545237 bayes_pls_golite062009
  • polysaccharide binding
    		•  1.34665327732001 bayes_pls_golite062009
  • binding
    		•  1.30738106455622 bayes_pls_golite062009
  • protein binding
    		•  1.30414885212044 bayes_pls_golite062009
  • signal transducer activity
    		•  1.30072283618388 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.30072283618388 bayes_pls_golite062009
  • serine-type aminopeptidase activity
    		•  0.964413112640311 bayes_pls_golite062009
  • growth factor activity
    		•  0.848900101748605 bayes_pls_golite062009
  • receptor binding
    		•  0.79054390509229 bayes_pls_golite062009
  • calcium ion binding
    		•  0.753095272942721 bayes_pls_golite062009
  • peptide binding
    		•  0.348186768259137 bayes_pls_golite062009
  • sodium channel regulator activity
    		•  0.30724450617383 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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