Protein Overview: GRM8_RAT

General Information:
Name(s) found:	GRM8_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|2495080\|sp\|P70579.1\|GRM8_RAT RecName: Full=Metabotropic glutamate receptor 8; Short=mGluR8; Flags: Precursor [NCBI NR] gi\|1575471\|gb\|AAB09537.1\| metabotropic glutamate receptor 8 [Rattus norvegicus] [NCBI NR] gi\|11559972\|ref\|NP_071538.1\| glutamate receptor, metabotropic 8 [Rattus norvegicus] [NCBI NR] Metabotropic glutamate receptor 8 precursor (mGluR8) - Rattus norvegicus (Rat) [Swiss-Prot] Metabotropic glutamate receptor 8 OS=Rattus norvegicus GN=Grm8 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):4-58188848 Metabotropic glutamate receptor 8 precursor [hmr_yeast5_DM3-1_pombe.fasta] metabotropic glutamate receptor 8; G protein-coupled receptor, family C, group 1, member H; G protein-coupled receptor family C group 1 member H [HMR_022704-rand.fasta] metabotropic glutamate receptor 8; G protein-coupled receptor family C group 1 member H; G protein-coupled receptor, family C, group 1, member H [071204_hmrz_cont.fasta] glutamate receptor, metabotropic 8 [Rattus norvegicus]gi\|1575471\|gb\|AAB09537.1\| metabotropic glutamate receptor 8 [Rattus norvegicus]gi\|2495080\|sp\|P70579\|MGR8_RAT Metabotropic glutamate receptor 8 precursor (mGluR8) [nrdb_11152004_Chlamydomonas] (NM_022202) metabotropic glutamate receptor 8 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 Metabotropic glutamate receptor 8 precursor [EBI-IPI_rat_3.05_04-04-2005_origrev.fasta] glutamate receptor, metabotropic 8 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Metabotropic glutamate receptor 8 precursor (mGluR8) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] metabotropic glutamate receptor 8 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 METABOTROPIC GLUTAMATE RECEPTOR 8 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Metabotropic glutamate receptor 8 OS=Rattus norvegicus GN=Grm8 [011711_HMR.fasta] metabotropic glutamate receptor 8; G protein-coupled receptor family C group 1 member H; G protein-coupled receptor, family C, group 1, member H [Rattus norvegicus] [H3-CATD_Contrast.fasta]
Organism:	Rattus norvegicus
Length:	908 amino acids
Gene Ontology:
Cellular Component:	presynaptic membrane [IDA] integral to plasma membrane [IDA] postsynaptic membrane [TAS] neuronal cell body [IDA] neuron projection [IDA] plasma membrane [IEA]
Biological Process:	neuroprotection [TAS] regulation of neurotransmitter secretion [IDA] G-protein coupled receptor protein signaling pathway [IEA] signal transduction [IEA] inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway [TAS] sensory perception of smell [IEA] synaptic transmission [IDA][NAS] sensory perception of pain [TAS] negative regulation of cAMP biosynthetic process [UNKNOWN][IEA] response to stimulus [IEA] synaptic transmission, glutamatergic [IDA]
Molecular Function:	group III metabotropic glutamate receptor activity [UNKNOWN][IDA] G-protein coupled receptor activity [IEA] receptor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVCEGKRLAS CPCFFLLTAK FYWILTMMQR THSQEYAHSI RVDGDIILGG LFPVHAKGER  60
   61 GVPCGELKKE KGIHRLEAML YAIDQINKDP DLLSNITLGV RILDTCSRDT YALEQSLTFV 120
  121 QALIEKDASD VKCANGDPPI FTKPDKISGV IGAAASSVSI MVANILRLFK IPQISYASTA 180
  181 PELSDNTRYD FFSRVVPPDS YQAQAMVDIV TALGWNYVST LASEGNYGES GVEAFTQISR 240
  241 EIGGVCIAQS QKIPREPRPG EFEKIIKRLL ETPNARAVIM FANEDDIRRI LEAAKKLNQS 300
  301 GHFLWIGSDS WGSKIAPVYQ QEEIAEGAVT ILPKRASIDG FDRYFRSRTL ANNRRNVWFA 360
  361 EFWEENFGCK LGSHGKRNSH IKKCTGLERI ARDSSYEQEG KVQFVIDAVY SMAYALHNMH 420
  421 KERCPGYIGL CPRMVTIDGK ELLGYIRAVN FNGSAGTPVT FNENGDAPGR YDIFQYQINN 480
  481 KSTEYKIIGH WTNQLHLKVE DMQWANREHT HPASVCSLPC KPGERKKTVK GVPCCWHCER 540
  541 CEGYNYQVDE LSCELCPLDQ RPNINRTGCQ RIPIIKLEWH SPWAVVPVFI AILGIIATTF 600
  601 VIVTFVRYND TPIVRASGRE LSYVLLTGIF LCYSITFLMI AAPDTIICSF RRIFLGLGMC 660
  661 FSYAALLTKT NRIHRIFEQG KKSVTAPKFI SPASQLVITF SLISVQLLGV FVWFVVDPPH 720
  721 TIIDYGEQRT LDPENARGVL KCDISDLSLI CSLGYSILLM VTCTVYAIKT RGVPETFNEA 780
  781 KPIGFTMYTT CIIWLAFIPI FFGTAQSAEK MYIQTTTLTV SMSLSASVSL GMLYMPKVYI 840
  841 IIFHPEQNVQ KRKRSFKAVV TAATMQSKLI QKGNDRPNGE VKSELCESLE TNTSSTKTTY 900
  901 ISYSNHSI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: GRM8_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: