General Information: |
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Name(s) found: |
gi|157824041
[NCBI NR]
gi|149045237 [NCBI NR] gi|109505704 [NCBI NR] gi|109504856 [NCBI NR] |
Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 658 amino acids |
Gene Ontology: |
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Cellular Component: |
cytoplasm
[UNKNOWN]
mitochondrion [UNKNOWN] membrane raft [IDA] cytosol [UNKNOWN] death-inducing signaling complex [UNKNOWN] receptor complex [UNKNOWN] protein complex [IDA] |
Biological Process: |
signal transduction
[IEA]
positive regulation of I-kappaB kinase/NF-kappaB cascade [UNKNOWN] protein amino acid autophosphorylation [UNKNOWN] protein heterooligomerization [IPI] protein amino acid phosphorylation [IEA] I-kappaB kinase/NF-kappaB cascade [UNKNOWN] positive regulation of NF-kappaB transcription factor activity [UNKNOWN] induction of necroptosis by extracellular signals [UNKNOWN] activation of pro-apoptotic gene products [UNKNOWN] induction of apoptosis [UNKNOWN] apoptosis [UNKNOWN] positive regulation of necrotic cell death [UNKNOWN] response to tumor necrosis factor [UNKNOWN] |
Molecular Function: |
ATP binding
[IEA]
protein binding [UNKNOWN][IEA][IPI] protein kinase activity [UNKNOWN] death receptor binding [UNKNOWN] protein serine/threonine kinase activity [UNKNOWN][IEA] receptor activity [IEA] death domain binding [UNKNOWN] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MQPDMSLDNI KMASDDLLER KDLDSGGFGK VSLCFHRTHG FVILKKVYTG PNRAEYNEAL 60 61 LEEGKMMHRL RHDRVVKLLG IIIEEGNYSL VMEYMEQGNL MHVLKTKESV PLSVKGRIIV 120 121 EIIEGMHYLH DEGVIHKDLK PENILVDRDF HIKIADLGVA SFKTWSKLTK EEHNKQREAS 180 181 SVTKKNGGTL YYMAPEHLTD INTKPTEKSD VYSFAIVLWA IFANKEPYEN VICTEQFLVC 240 241 INSGNRPNVE DILEFCPREI ISLMERCWQT NPEDRPTFFG IEKEFKPFYL SQFEEYVEED 300 301 VASLKKEYPS QSPVLKRMFS LQHDCVPLPP SRSNSEQPGS LHSSQGLPMG PVEESWFSSS 360 361 PEYPQEENER SVQAKLQEEA SYHAFGIFAE KQTKSQPRLN EAYNREEERK RRVSHDPFAQ 420 421 QRVHENVKSA GAKGLPYPST TSHGNAAHQL SGPASQIKVP LWNNGVYNHH GFGATGTGVW 480 481 YGPSVSQSYN AYKTPVPETN LPGSIPTMPY ISLAPPDDSI RCTIYNSSRV QIGNYNYMDL 540 541 GPSSQPPTNT CKVESTSRHQ AVFANTTSLT DKHLNPIREN MGKQWKNCAR KLGFTESQID 600 601 EIDHDYERDG LKEKVYQMLQ KWLMREGTKG ATVGKLAQAL HQCCRTDLLN QLIQASQS |
NOT SHOWING SINGLE HITS. [ Show Single Hits ]
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Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.99 |
Source: Reynolds et al. (2008)