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Protein Overview: MYD88_RAT

General Information:
Name(s) found: MYD88_RAT [Swiss-Prot]
Description(s) found:
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  • gi|67678198|gb|AAH97266.1| Myeloid differentiation primary response gene 88 [Rattus norvegicus] [NCBI NR]
  • gi|149018276|gb|EDL76917.1| myeloid differentiation primary response gene 88 [Rattus norvegicus] [NCBI NR]
  • Myeloid differentiation primary response protein MyD88 OS=Rattus norvegicus GN=Myd88 PE=2 SV=2 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):8-126917346 [hmr_yeast5_DM3-1_pombe.fasta]
  • Tax_Id=10116 Myeloid differentiation primary response gene 88 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • Tax_Id=10116 Hypothetical protein [EBI-IPI_rat_3.08_07-12-2005_origrev_con.fasta]
  • myeloid differentiation primary response gene 88 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Myeloid differentiation primary response gene 88 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 Gene_Symbol=Myd88 Myeloid differentiation primary response gene 88 [rat-ipi-250309-contam.fasta]
  • Myeloid differentiation primary response protein MyD88 OS=Rattus norvegicus GN=Myd88 [011711_HMR.fasta]
    • Organism: Rattus norvegicus
    Length: 296 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    cytosol [UNKNOWN]
    intrinsic to membrane [IEA]
    Biological Process: Toll signaling pathway [IDA]
    response to peptidoglycan [UNKNOWN][IEA]
    positive regulation of I-kappaB kinase/NF-kappaB cascade [UNKNOWN][TAS]
    JNK cascade [IMP]
    response to virus [UNKNOWN][IEA]
    positive regulation of transcription from RNA polymerase II promoter [IMP]
    positive regulation of NF-kappaB transcription factor activity [UNKNOWN][IEA]
    positive regulation of smooth muscle cell proliferation [IMP]
    inflammatory response [IEA]
    response to molecule of fungal origin [UNKNOWN][IEA]
    MyD88-dependent toll-like receptor signaling pathway [UNKNOWN][IEA]
    anti-apoptosis [UNKNOWN]
    positive regulation of lymphocyte proliferation [UNKNOWN][IEA]
    cytokine-mediated signaling pathway [IMP]
    type I interferon biosynthetic process [UNKNOWN][IEA]
    positive regulation of tumor necrosis factor production [UNKNOWN][IEA]
    defense response to Gram-positive bacterium [UNKNOWN][IEA]
    signal transduction [IEA]
    cell surface receptor linked signaling pathway [UNKNOWN]
    I-kappaB kinase/NF-kappaB cascade [UNKNOWN]
    regulation of cell proliferation [UNKNOWN][IEA]
    negative regulation of growth of symbiont in host [UNKNOWN][IEA]
    innate immune response [IEA]
    positive regulation of JNK cascade [UNKNOWN][IEA]
    immunoglobulin mediated immune response [UNKNOWN][IEA]
    response to interleukin-1 [UNKNOWN]
    lipopolysaccharide-mediated signaling pathway [UNKNOWN][IEA]
    response to lipopolysaccharide [UNKNOWN][IEA]
    positive regulation of interleukin-6 production [UNKNOWN][IEA]
    positive regulation of chemokine biosynthetic process [UNKNOWN][IEA]
    Molecular Function: transmembrane receptor activity [IEA]
    protein binding [UNKNOWN][IPI]
    Toll binding [IDA]
    receptor binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAGGPRVGS VSVDSYLFSL PLVALNVGVR RRLSLFLNPR TTAAADWTSL AEEMGFEYLE  60
   61 IREFETRPDP TRSLLDAWQG RSGSSVGRLL ELLALLDRED ILYELKDRIE EDCQKYIRNQ 120
  121 QKQESEKPLQ VARVESSVPQ TKELGGITTL DDPLGQTPEL FDAFICYCPS DIEFVQEMIR 180
  181 QLEQTDYRLK LCVSDRDVLP GTCVWSIASE LIEKRCRRMV VVVSDDYLQS KECDFQTKFA 240
  241 LSLSPGVQQK RLIPIKYKAM KKDFPSILRF ITICDYTNPC TKSWFWTRLA KALSLP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.72

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle