Protein Overview: VDR_RAT

General Information:
Name(s) found:	VDR_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|A31761 1,25-dihydroxyvitamin D-3 receptor - rat [NCBI NR] gi\|8394529\|ref\|NP_058754.1\| vitamin D (1,25- dihydroxyvitamin D3) receptor [Rattus norvegicus] [NCBI NR] gi\|203957\|gb\|AAA41089.1\| 1,25-dihydroxyvitamin D-3 receptor [NCBI NR] gi\|137618\|sp\|P13053.1\|VDR_RAT RecName: Full=Vitamin D3 receptor; Short=VDR; AltName: Full=1,25-dihydroxyvitamin D3 receptor; AltName: Full=Nuclear receptor subfamily 1 group I member 1 [NCBI NR] Vitamin D3 receptor OS=Rattus norvegicus GN=Vdr PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):7-126809294 Vitamin D3 receptor [hmr_yeast5_DM3-1_pombe.fasta] vitamin D receptor; vitamin D (1,25-dihydroxyvitamin D3) receptor; Vitamin D (125-dihydroxyvitamin D3) receptor [HMR_022704-rand.fasta] vitamin D receptor; Vitamin D (125-dihydroxyvitamin D3) receptor; vitamin D (1,25-dihydroxyvitamin D3) receptor [071204_hmrz_cont.fasta] vitamin D receptor [Rattus norvegicus]gi\|137618\|sp\|P13053\|VDR_RAT Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor)gi\|91894\|pir\|\|A31761 1,25-dihydroxyvitamin D-3 receptor - ratgi\|203957\|gb\|AAA41089.1\| 1,25-dihydroxyvitamin D-3 receptor [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Vitamin D3 receptor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_017058) vitamin D receptor; Vitamin D (1,25-dihydroxyvitamin D3) receptor [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor) (Nuclear receptor subfamily 1 group I member 1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] vitamin D receptor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] 1,25-dihydroxyvitamin D-3 receptor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 VITAMIN D3 RECEPTOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] vitamin D (1,25- dihydroxyvitamin D3) receptor [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Vdr Vitamin D3 receptor [rat-ipi-250309-contam.fasta] Vitamin D3 receptor OS=Rattus norvegicus GN=Vdr [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	423 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IEA] nuclear chromosome [TAS] nuclear heterochromatin [IDA]
Biological Process:	positive regulation of apoptosis involved in mammary gland involution [UNKNOWN][IEA] multicellular organismal development [UNKNOWN][IEA] negative regulation of cell proliferation [UNKNOWN][IEA] regulation of calcidiol 1-monooxygenase activity [IEA] mammary gland branching involved in pregnancy [UNKNOWN][IEA] lactation [UNKNOWN][IEA] decidualization [UNKNOWN][IEA] regulation of transcription from RNA polymerase II promoter [TAS] cellular calcium ion homeostasis [UNKNOWN][IEA] organ morphogenesis [UNKNOWN][IEA] induction of apoptosis by hormones [IDA] intestinal absorption [UNKNOWN][IEA] skeletal system development [UNKNOWN][IEA] negative regulation of transcription [UNKNOWN][IEA] calcium ion transport [UNKNOWN][IEA] vitamin D receptor signaling pathway [UNKNOWN][IEA] positive regulation of vitamin D 24-hydroxylase activity [UNKNOWN][IEA] negative regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN][IEA]
Molecular Function:	zinc ion binding [IEA] vitamin D3 receptor activity [UNKNOWN][IDA][TAS] sequence-specific DNA binding [IDA] vitamin D binding [IDA][IMP][TAS] retinoid X receptor binding [UNKNOWN][IEA] DNA binding [UNKNOWN] transcription factor activity [UNKNOWN][TAS] protein binding [UNKNOWN][IEA] ligand-dependent nuclear receptor activity [UNKNOWN] transcription regulator activity [UNKNOWN] metal ion binding [IEA] steroid hormone receptor activity [IEA] vitamin D response element binding [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEATAASTSL PDPGDFDRNV PRICGVCGDR ATGFHFNAMT CEGCKGFFRR SMKRKALFTC  60
   61 PFNGDCRITK DNRRHCQACR LKRCVDIGMM KEFILTDEEV QRKREMIMKR KEEEALKDSL 120
  121 RPKLSEEQQH IIAILLDAHH KTYDPTYADF RDFRPPVRMD GSTGSYSPRP TLSFSGNSSS 180
  181 SSSDLYTTSL DMMEPSGFSN LDLNGEDSDD PSVTLDLSPL SMLPHLADLV SYSIQKVIGF 240
  241 AKMIPGFRDL TSDDQIVLLK SSAIEVIMLR SNQSFTMDDM SWDCGSQDYK YDVTDVSKAG 300
  301 HTLELIEPLI KFQVGLKKLN LHEEEHVLLM AICIVSPDRP GVQDAKLVEA IQDRLSNTLQ 360
  361 TYIRCRHPPP GSHQLYAKMI QKLADLRSLN EEHSKQYRSL SFQPENSMKL TPLVLEVFGN 420
  421 EIS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: VDR_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: