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Protein Overview: gi|149062718, gi...

General Information:
Name(s) found: gi|28144231 [NCBI NR]
gi|2772900 [NCBI NR]
gi|149062718 [NCBI NR]
gi|13928830 [NCBI NR]
Description(s) found:
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  • gi|28144231|gb|AAO31948.1|AF455569_1 protein tyrosine phosphatase and tensin-like protein [Rattus norvegicus] [NCBI NR]
  • gi|2772900|gb|AAB96620.1| protein tyrosine phosphatase and tensin homolog/mutated in multiple advanced cancers protein [Rattus norvegicus] [NCBI NR]
  • gi|149062718|gb|EDM13141.1| phosphatase and tensin homolog, isoform CRA_a [Rattus norvegicus] [NCBI NR]
  • gi|13928830|ref|NP_113794.1| phosphatase and tensin homolog [Rattus norvegicus] [NCBI NR]
  • Ensembl_locations(Chr-bp):1-269925590 Protein tyrosine phosphatase and tensin homolog/mutated in multiple advanced cancers protein [hmr_yeast5_DM3-1_pombe.fasta]
  • phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; mutated in multiple advanced cancers 1 [HMR_022704-rand.fasta]
  • phosphatase and tensin homolog [Rattus norvegicus]gi|28144231|gb|AAO31948.1| protein tyrosine phosphatase and tensin-like protein [Rattus norvegicus]gi|2772900|gb|AAB96620.1| protein tyrosine phosphatase and tensin homolog/mutated in multiple advanced c [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 Protein tyrosine phosphatase and tensin homolog/mutated in multiple advanced cancers protein [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • (NM_031606) phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1) [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • phosphatase and tensin homolog [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • phosphatase and tensin homolog, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • protein tyrosine phosphatase and tensin-like protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • protein tyrosine phosphatase and tensin homolog/mutated in multiple advanced cancers protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 PROTEIN TYROSINE PHOSPHATASE AND TENSIN HOMOLOG/MUTATED IN MULTIPLE ADVANCED CANCERS PROTEIN [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10116 Gene_Symbol=Pten Protein tyrosine phosphatase and tensin-like protein [rat-ipi-250309-contam.fasta]
  • Phosphatase and tensin homolog, isoform CRA_a OS=Rattus norvegicus GN=Pten [011711_HMR.fasta]
  • Phosphatase and tensin homolog, isoform CRA_a OS=Rattus norvegicus GN=Pten PE=1 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
    • Organism: Rattus norvegicus
    Length: 403 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IDA]
    cytoplasm [UNKNOWN][IDA]
    mitochondrion [IDA]
    cytosol [UNKNOWN]
    Biological Process: response to zinc ion [IEP]
    negative regulation of cell proliferation [UNKNOWN][IDA]
    endothelial cell migration [UNKNOWN]
    memory [IMP]
    cardiac muscle tissue development [UNKNOWN]
    inositol phosphate dephosphorylation [UNKNOWN]
    phosphoinositide dephosphorylation [UNKNOWN]
    heart development [UNKNOWN]
    response to ethanol [IEP]
    response to glucose stimulus [IEP]
    angiogenesis [UNKNOWN]
    induction of apoptosis [UNKNOWN][TAS]
    response to arsenic [IEP]
    regulation of cell cycle [UNKNOWN]
    response to inorganic substance [IEP]
    cell migration [UNKNOWN]
    response to organic substance [IEP]
    neuron projection development [IDA]
    response to ATP [IEP]
    regulation of myeloid cell apoptosis [UNKNOWN]
    protein amino acid dephosphorylation [UNKNOWN]
    platelet-derived growth factor receptor signaling pathway [IDA]
    response to nutrient [IEP]
    prostate gland growth [UNKNOWN]
    response to organic cyclic substance [IEP]
    aging [IEP]
    negative regulation of focal adhesion assembly [UNKNOWN]
    central nervous system development [UNKNOWN]
    regulation of protein stability [UNKNOWN]
    response to drug [IEP]
    regulation of B cell apoptosis [UNKNOWN]
    positive regulation of apoptosis [IMP]
    negative regulation of epithelial cell proliferation [UNKNOWN]
    response to estradiol stimulus [IEP]
    negative regulation of cell migration [UNKNOWN][TAS]
    negative regulation of phagocytosis [IMP]
    negative regulation of protein kinase B signaling cascade [UNKNOWN]
    Molecular Function: protein serine/threonine phosphatase activity [UNKNOWN]
    phosphatidylinositol-3-phosphatase activity [UNKNOWN]
    inositol or phosphatidylinositol phosphatase activity [IDA]
    protein binding [UNKNOWN][IPI]
    platelet-derived growth factor receptor binding [IDA]
    protein tyrosine phosphatase activity [UNKNOWN]
    PDZ domain binding [UNKNOWN]
    inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [UNKNOWN]
    phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [UNKNOWN]
    protein tyrosine/serine/threonine phosphatase activity [TAS]
    phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAIIKEIVS RNKRRYQEDG FDLDLTYIYP NIIAMGFPAE RLEGVYRNNI DDVVRFLDSK  60
   61 HKNHYKIYNL CAERHYDTAK FNCRVAQYPF EDHNPPQLEL IKPFCEDLDQ WLSEDDNHVA 120
  121 AIHCKAGKGR TGVMICAYLL HRGKFLKAQE ALDFYGEVRT RDKKGVTIPS QRRYVYYYSY 180
  181 LLKNHLDYRP VALLFHKMMF ETIPMFSGGT CNPQFVVCQL KVKIYSSNSG PTRREDKLMY 240
  241 FEFPQPLPVC GDIKVEFFHK QNKMLKKDKM FHFWVNTFFI PGPEETSEKV ENGSLCDQEI 300
  301 DSICSIERAD NDKEYLVLTL TKNDLDKANK DKANRYFSPN FKVKLYFTKT VEEPSNPEAS 360
  361 SSTSVTPDVS DNEPDHYRYS DTTDSDPENE PFDEDQHSQI TKV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle