Protein Overview: PDK4_RAT

General Information:
Name(s) found:	PDK4_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|2772938\|gb\|AAC00177.1\| pyruvate dehydrogenase kinase isoenzyme 4 [Rattus norvegicus] [NCBI NR] gi\|16758318\|ref\|NP_446003.1\| pyruvate dehydrogenase kinase 4 [Rattus norvegicus] [NCBI NR] gi\|12585291\|sp\|O54937.1\|PDK4_RAT RecName: Full=[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial; AltName: Full=Pyruvate dehydrogenase kinase isoform 4; Flags: Precursor [NCBI NR] [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial OS=Rattus norvegicus GN=Pdk4 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):4-30472164 [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial precursor [hmr_yeast5_DM3-1_pombe.fasta] pyruvate dehydrogenate kinase 4; pyruvate dehydrogenase kinase, isoenzyme 4; pyruvate dehydrogenase kinase isoenzyme 4 [HMR_022704-rand.fasta] pyruvate dehydrogenate kinase 4 [Rattus norvegicus]gi\|12585291\|sp\|O54937\|PDK4_RAT [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial precursor (Pyruvate dehydrogenase kinase isoform 4)gi\|2772938\|gb\|AAC00177.1\| pyruvate dehydrogenase ki [nrdb_11152004_Chlamydomonas] Tax_Id=10116 [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_053551) pyruvate dehydrogenate kinase 4; pyruvate dehydrogenase kinase, isoenzyme 4 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial precursor (Pyruvate dehydrogenase kinase isoform 4) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] pyruvate dehydrogenase kinase, isoenzyme 4 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] pyruvate dehydrogenase kinase isoenzyme 4 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 [PYRUVATE DEHYDROGENASE [LIPOAMIDE]] KINASE ISOZYME 4, MITOCHONDRIAL PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] pyruvate dehydrogenase kinase, isozyme 4 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] pyruvate dehydrogenate kinase 4 [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Pdk4 [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial [rat-ipi-250309-contam.fasta] [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial OS=Rattus norvegicus GN=Pdk4 [011711_HMR.fasta] [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial OS=Rattus norvegicus GN=Pdk4 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	412 amino acids
Gene Ontology:
Cellular Component:	mitochondrial matrix [IEA] mitochondrion [UNKNOWN][IDA] mitochondrial inner membrane [UNKNOWN][IEA]
Biological Process:	carbohydrate metabolic process [IEA] acetyl-CoA biosynthetic process from pyruvate [TAS] signal transduction [IEA] glucose metabolic process [IEA] protein amino acid phosphorylation [IDA][IMP] regulation of acetyl-CoA biosynthetic process from pyruvate [UNKNOWN] peptidyl-histidine phosphorylation [IEA]
Molecular Function:	two-component sensor activity [IEA] nucleotide binding [IEA] ATP binding [UNKNOWN][IDA][IMP] protein kinase activity [UNKNOWN] pyruvate dehydrogenase (acetyl-transferring) kinase activity [IDA][IMP] transferase activity [IEA] kinase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKAARFVMRS ASSLGNAGLV PREVELFSRY SPSPLSMKQL LDFGSENACE RTSFSFLRQE  60
   61 LPVRLANILK EIDILPEHLV NTPSVQLVKS WYIQSLMDLV EFHEKSPEDQ KVLSDFVDTL 120
  121 VKVRNRHHNV VPTMAQGILE YKDNCTVDPV TNQNLQYFLD RFYMNRISTR MLMNQHILIF 180
  181 SDSKTGNPSH IGSIDPNCDV VAVVEDAFEC AKMLCDQYYL TSPELKLTQV NGKFPGQPIH 240
  241 IVYVPSHLHH MLFELFKNAM RATVEHQENR PFLTPVEATV VLGKEDLTIK ISDRGGGVPL 300
  301 RITDRLFSYT YSTAPTPVMD NSRNAPLAGF GYGLPISRLY AKYFQGDLNL YSMSGYGTDA 360
  361 IIYLKALSSE SIEKLPVFNK SAFKHYQMSS EADDWCIPSK EPKNLSKEKL AV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.81

Protein Overview: PDK4_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: