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Protein Overview: GBG8_RAT

General Information:
Name(s) found: GBG8_RAT [Swiss-Prot]
Description(s) found:
Found 25 descriptions.
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  • Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 OS=Rattus norvegicus GN=Gng8 PE=2 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 70 amino acids

    Gene Ontology:
    Cellular Component: heterotrimeric G-protein complex [TAS]
    plasma membrane [IEA]
    Biological Process: G-protein coupled receptor protein signaling pathway [IEA]
    signal transduction [IEA]
    nervous system development [IEP]
    hormone-mediated signaling pathway [UNKNOWN]
    Molecular Function: signal transducer activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNNMAKIAE ARKTVEQLKL EVNIDRMKVS QAAAELLAFC ETHAKDDPLV TPVPAAENPF  60
   61 RDKRLFCTLL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..70] PSI-BLAST 25.30103 The Crystal Structure of a Biologically Active Peptide (SIGK) Bound to a G Protein Beta:Gamma Heterodimer

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • GTPase activity
    		•  5.98519752009234 bayes_pls_golite062009
  • angiotensin receptor binding
    		•  3.57083467421742 bayes_pls_golite062009
  • type 1 angiotensin receptor binding
    		•  3.57083467421742 bayes_pls_golite062009
  • signal transducer activity
    		•  1.75801578312445 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.75801578312445 bayes_pls_golite062009
  • binding
    		•  1.46430715205084 bayes_pls_golite062009
  • receptor binding
    		•  1.45302453757621 bayes_pls_golite062009
  • catalytic activity
    		•  0.467010875265274 bayes_pls_golite062009
  • protein binding
    		•  0.399162858691971 bayes_pls_golite062009
  • hydrolase activity
    		•  0.179751786037418 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle