Protein Overview: IL4RA_RAT

General Information:
Name(s) found:	IL4RA_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|50400208\|sp\|Q63257.2\|IL4RA_RAT RecName: Full=Interleukin-4 receptor alpha chain; Short=IL-4R-alpha; AltName: CD_antigen=CD124; Flags: Precursor [NCBI NR] gi\|4996119\|dbj\|BAA78338.1\| inetrleukin-4 receptor (membrane-bound form) [Rattus norvegicus] [NCBI NR] gi\|158534071\|ref\|NP_596871.2\| interleukin 4 receptor [Rattus norvegicus] [NCBI NR] gi\|149067964\|gb\|EDM17516.1\| interleukin 4 receptor, alpha, isoform CRA_c [Rattus norvegicus] [NCBI NR] gi\|149067963\|gb\|EDM17515.1\| interleukin 4 receptor, alpha, isoform CRA_c [Rattus norvegicus] [NCBI NR] (Q63257) Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) [Swiss-Prot] Interleukin-4 receptor subunit alpha OS=Rattus norvegicus GN=Il4r PE=2 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):1-178377150;1-178377150 Inetrleukin-4 receptor [hmr_yeast5_DM3-1_pombe.fasta] inetrleukin-4 receptor (membrane-bound form) [Rattus norvegicus]gi\|50400208\|sp\|Q63257\|IL4R_RAT Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform 1 of Interleukin-4 receptor alpha chain precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] interleukin 4 receptor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] interleukin 4 receptor, alpha, isoform CRA_c [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] inetrleukin-4 receptor (membrane-bound form) [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF INTERLEUKIN-4 RECEPTOR ALPHA CHAIN PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Il4ra Isoform 1 of Interleukin-4 receptor alpha chain [rat-ipi-250309-contam.fasta] interleukin-4 receptor subunit alpha precursor [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Isoform 1 of Interleukin-4 receptor subunit alpha OS=Rattus norvegicus GN=Il4r [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	801 amino acids
Gene Ontology:
Cellular Component:	extracellular space [IDA] integral to membrane [IEA] extracellular region [IEA] plasma membrane [IEA]
Biological Process:	inflammatory response [TAS] immune response [TAS] positive regulation of T-helper 2 cell differentiation [UNKNOWN][IEA] negative regulation of T-helper 1 cell differentiation [UNKNOWN][IEA] regulation of cell proliferation [IDA]
Molecular Function:	protein binding [UNKNOWN][IEA] interleukin-4 receptor activity [TAS] protein heterodimerization activity [TAS] receptor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGWLCTKFLS SVSCLILLWV TGSGGIKVLG DPTCFSDYIR TSTCEWQLDS TVDCSSQLLL  60
   61 DYRLLFEFSE NLTCTPKNSA DTVCVCQMAI EEPIQADTYW LELWSERGQL WQGSFKPSDN 120
  121 VKPPAPDNLT LHTNVSNALL LMWSNPYPSN NFLHKGLICM VNISREDNPA EFKVYNVTYT 180
  181 EPKLSFPVNT LTSGVRYRAR VRVLSQSFPG IWSEWSPSIT WYNHFQLPLL QRLPLGVSIS 240
  241 CICILLFCLT CYFSIIKIKK IWWDQIPTPA RSPLAAIIIQ DTKVSLWEKQ TRSQESTKSR 300
  301 HWKTCLTKLL PCLLEHRVKK ERESPKAAKT KPLQSPEKAG WYPAEVSRTV LWPENVHVSV 360
  361 VRCMELFEAP VQNVEEEEDE MVKGDLSMSP ENSGGGFQES QADIMARLTE NLFSDLLGAE 420
  421 NGGVGQSSMA ESSSLLPSES GQASTSWACF PTGPSETTCQ VTGQQPPHPD PERATGTACT 480
  481 QVPLVISDNP AYRSFSDFSS PAPNPGELAS EQKQAGHLEE GDLLSPVDPH SSGPPMQQAE 540
  541 SWEQILHMSV LQHGTAGSTP APTSGYQEFV QAVKQGASQD AGVPGVGPSG DTGYKAFSSL 600
  601 LSSSGVCTDT AAAGTDSGCG GYKPFQNPVP NQSPNSMPLF TFGLDMELPP SPLNSAPPNS 660
  661 TPECLGLELG LKGGTWLKAP PPSEQVPKPF GDDLGLGIVY SSLTCHLCGH LKQHHSQEED 720
  721 GQIHVVASPG CGCCYDEKSP SLGNLSGTLE SCPGEMSQEA NLTLAPRTPS NLSGVGKGPG 780
  781 HSPVPSQTTE VPVGTLGVTV S

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: IL4RA_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: