Protein Overview: PITX2_RAT

General Information:
Name(s) found:	PITX2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|5706494\|emb\|CAB52283.1\| homeodomain protein Ptx2A [Rattus norvegicus] [NCBI NR] gi\|17380159\|sp\|Q9R0W1.1\|PITX2_RAT RecName: Full=Pituitary homeobox 2; AltName: Full=Paired-like homeodomain transcription factor 2; AltName: Full=Homeobox protein PITX2; AltName: Full=rPtx2 [NCBI NR] gi\|149025927\|gb\|EDL82170.1\| paired-like homeodomain transcription factor 2, isoform CRA_c [Rattus norvegicus] [NCBI NR] gi\|109948271\|ref\|NP_001035970.1\| paired-like homeodomain transcription factor 2 isoform 1 [Rattus norvegicus] [NCBI NR] (Q9R0W1) Pituitary homeobox 2 (rPtx2) [Swiss-Prot] Pituitary homeobox 2 OS=Rattus norvegicus GN=Pitx2 PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):2-221998758 Splice isoform PTX2A of Q9R0W1 [hmr_yeast5_DM3-1_pombe.fasta] homeodomain protein Ptx2A [Rattus norvegicus]gi\|17380159\|sp\|Q9R0W1\|PIX2_RAT Pituitary homeobox 2 (rPtx2) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform PTX2A of Pituitary homeobox 2 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Pituitary homeobox 2 (rPtx2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] paired-like homeodomain transcription factor 2 isoform 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] paired-like homeodomain transcription factor 2, isoform CRA_c [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] homeodomain protein Ptx2A [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF PITUITARY HOMEOBOX 2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Pitx2 Isoform PTX2A of Pituitary homeobox 2 [rat-ipi-250309-contam.fasta] pituitary homeobox 2 isoform 1 [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Isoform PTX2A of Pituitary homeobox 2 OS=Rattus norvegicus GN=Pitx2 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	324 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IEA] transcription factor complex [UNKNOWN][IEA]
Biological Process:	multicellular organismal development [IEA] left lung morphogenesis [UNKNOWN][IEA] pulmonary myocardium development [UNKNOWN][IEA] anatomical structure morphogenesis [UNKNOWN] vasculogenesis [UNKNOWN] odontogenesis [UNKNOWN][IEA] regulation of transcription [UNKNOWN] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][IEA] heart development [UNKNOWN][IEA] patterning of blood vessels [UNKNOWN][IEA] in utero embryonic development [UNKNOWN][IEA] digestive system development [UNKNOWN][IEA] Wnt receptor signaling pathway [UNKNOWN][IEA] cardiac muscle cell differentiation [UNKNOWN][IEA] embryonic hindlimb morphogenesis [UNKNOWN] lung development [UNKNOWN][IEA] atrial cardiac muscle tissue morphogenesis [UNKNOWN][IEA] embryonic camera-type eye development [UNKNOWN][IEA] extraocular skeletal muscle development [UNKNOWN][IEA] regulation of transcription, DNA-dependent [UNKNOWN][IEA] pulmonary vein morphogenesis [UNKNOWN][IEA] determination of left/right symmetry [UNKNOWN][IEA] regulation of cell proliferation [UNKNOWN][IEA] superior vena cava morphogenesis [UNKNOWN][IEA] organ morphogenesis [UNKNOWN] pituitary gland development [UNKNOWN][IEA] skeletal muscle tissue development [UNKNOWN] regulation of cell migration [UNKNOWN][IEA]
Molecular Function:	transcription factor activity [UNKNOWN][IEA] protein binding [UNKNOWN][IEA] sequence-specific DNA binding [IEA] chromatin binding [UNKNOWN][IEA] transcription factor binding [UNKNOWN]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNCMKGPLPL EHRAAGTKLS AASSPFCHHT QALAMASVLA PGQPRSLDAS KHRLEVHTIS  60
   61 DTSSPEVAEK DKGQQGKNED VGAEDPSKKK RQRRQRTHFT SQQLQELEAT FQRNRYPDMS 120
  121 TREEIAVWTN LTEARVRVWF KNRRAKWRKR ERNQQAELCK NGFGPQFNGL MQPYDDMYPG 180
  181 YSYNNWAAKG LTSASLSTKS FPFFNSMNVN PLSSQSMFSP PNSISSMSMS SSMVPSAVTG 240
  241 VPGSSLNSLN NLNNLSSPSL NSAVPTPACP YAPPTPPYVY RDTCNSSLAS LRLKAKQHSS 300
  301 FGYASVQNPA SNLSACQYAV DRPV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.58

Protein Overview: PITX2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: