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Protein Overview: KPCD_RAT

General Information:
Name(s) found: KPCD_RAT [Swiss-Prot]
Description(s) found:
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  • pir||KIRTCD protein kinase C (EC 2.7.1.-) delta [validated] - rat [NCBI NR]
  • gi|18959250|ref|NP_579841.1| protein kinase C, delta [Rattus norvegicus] [NCBI NR]
  • gi|125554|sp|P09215.1|KPCD_RAT RecName: Full=Protein kinase C delta type; AltName: Full=nPKC-delta [NCBI NR]
  • Protein kinase C delta type OS=Rattus norvegicus GN=Prkcd PE=1 SV=1 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):16-5901461;16-5901461 Splice isoform 1 of P09215 [hmr_yeast5_DM3-1_pombe.fasta]
  • protein kinase C, delta [HMR_022704-rand.fasta]
  • protein kinase C, delta [Rattus norvegicus]gi|66730|pir||KIRTCD protein kinase C (EC 2.7.1.-) delta [validated] - ratgi|125554|sp|P09215|KPCD_RAT Protein kinase C, delta type (nPKC-delta)gi|206181|gb|AAA41871.1| protein kinase C delta subspecies [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 Splice Isoform 1 of Protein kinase C delta type [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • (NM_133307) protein kinase C, delta [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • Tax_Id=10116 Splice Isoform 1 of Protein kinase C, delta type [EBI-IPI_rat_3.08_07-12-2005_origrev_con.fasta]
  • protein kinase C, delta [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Protein kinase C delta type (nPKC-delta) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 SPLICE ISOFORM 1 OF PROTEIN KINASE C, DELTA TYPE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10116 Gene_Symbol=Prkcd Isoform 1 of Protein kinase C delta type [rat-ipi-250309-contam.fasta]
  • Isoform 1 of Protein kinase C delta type OS=Rattus norvegicus GN=Prkcd [011711_HMR.fasta]
    • Organism: Rattus norvegicus
    Length: 673 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [IDA]
    nucleus [UNKNOWN][IDA]
    cytoplasm [UNKNOWN][IDA]
    mitochondrion [IDA]
    membrane [IEA]
    cytosol [UNKNOWN]
    plasma membrane [UNKNOWN]
    Biological Process: positive regulation of MAP kinase activity [IMP]
    response to amino acid stimulus [IEP]
    protein amino acid autophosphorylation [IDA]
    protein amino acid phosphorylation [UNKNOWN][IDA][IEA]
    response to mechanical stimulus [IEP]
    cellular response to insulin stimulus [IEP]
    response to oxidative stress [IMP]
    response to ethanol [IEP]
    response to heat [IEP]
    response to glucose stimulus [IEP]
    response to hypoxia [IEP]
    induction of apoptosis [IDA]
    collagen metabolic process [IMP]
    B cell proliferation [UNKNOWN]
    positive regulation of glucose import [IMP]
    response to organic cyclic substance [IEP]
    response to hydrogen peroxide [IEP]
    positive regulation of MAPKKK cascade [IMP]
    aging [IEP]
    cellular response to glucose starvation [IEP]
    intracellular signaling pathway [IDA]
    interleukin-12 production [UNKNOWN]
    response to drug [IEP]
    immunoglobulin mediated immune response [UNKNOWN]
    positive regulation of apoptosis [IMP]
    senescence [UNKNOWN]
    response to organic nitrogen [IEP]
    interleukin-10 production [UNKNOWN]
    aspartate transport [IMP]
    Molecular Function: nucleotide binding [IEA]
    calcium-independent protein kinase C activity [IDA]
    ATP binding [IEA]
    protein binding [UNKNOWN][IPI]
    protein C-terminus binding [UNKNOWN]
    metal ion binding [IEA]
    enzyme activator activity [UNKNOWN]
    protein serine/threonine kinase activity [IEA]
    transferase activity [IEA]
    protein kinase C activity [IEA]
    enzyme binding [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPFLRISFN SYELGSLQAE DDASQPFCAV KMKEALTTDR GKTLVQKKPT MYPEWKSTFD  60
   61 AHIYEGRVIQ IVLMRAAEDP MSEVTVGVSV LAERCKKNNG KAEFWLDLQP QAKVLMCVQY 120
  121 FLEDGDCKQS MRSEEEAMFP TMNRRGAIKQ AKIHYIKNHE FIATFFGQPT FCSVCKEFVW 180
  181 GLNKQGYKCR QCNAAIHKKC IDKIIGRCTG TATNSRDTIF QKERFNIDMP HRFKVYNYMS 240
  241 PTFCDHCGTL LWGLVKQGLK CEDCGMNVHH KCREKVANLC GINQKLLAEA LNQVTQKASR 300
  301 KPETPETVGI YQGFEKKTAV SGNDIPDNNG TYGKIWEGSN RCRLENFTFQ KVLGKGSFGK 360
  361 VLLAELKGKE RYFAIKYLKK DVVLIDDDVE CTMVEKRVLA LAWENPFLTH LICTFQTKDH 420
  421 LFFVMEFLNG GDLMFHIQDK GRFELYRATF YAAEIICGLQ FLHGKGIIYR DLKLDNVMLD 480
  481 KDGHIKIADF GMCKENIFGE NRASTFCGTP DYIAPEILQG LKYSFSVDWW SFGVLLYEML 540
  541 IGQSPFHGDD EDELFESIRV DTPHYPRWIT KESKDIMEKL FERDPAKRLG VTGNIRLHPF 600
  601 FKTINWNLLE KRKVEPPFKP KVKSPSDYSN FDPEFLNEKP QLSFSDKNLI DSMDQTAFKG 660
  661 FSFVNPKYEQ FLE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle