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Protein Overview: PTN_RAT

General Information:
Name(s) found: PTN_RAT [Swiss-Prot]
Description(s) found:
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  • gi|8394103|ref|NP_058762.1| pleiotrophin [Rattus norvegicus] [NCBI NR]
  • gi|52001086|sp|P63090.1|PTN_RAT RecName: Full=Pleiotrophin; Short=PTN; AltName: Full=Heparin-binding growth-associated molecule; Short=HB-GAM; AltName: Full=Heparin-binding growth factor 8; Short=HBGF-8; AltName: Full=Osteoblast-specific factor 1; Short=O [NCBI NR]
  • gi|38304038|gb|AAH62013.1| Pleiotrophin [Rattus norvegicus] [NCBI NR]
  • gi|204572|gb|AAA41310.1| heparin-binding growth associated molecule [NCBI NR]
  • gi|149065259|gb|EDM15335.1| pleiotrophin, isoform CRA_b [Rattus norvegicus] [NCBI NR]
  • pir||B37780 pleiotrophin precursor - rat [NCBI NR]
  • Pleiotrophin OS=Rattus norvegicus GN=Ptn PE=1 SV=1 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):4-68145887;4-68145887 Pleiotrophin precursor [hmr_yeast5_DM3-1_pombe.fasta]
  • pleiotrophin; Pleiotrophin (Heparine binding factor, Hbnf, in the mouse); heparin binding factor [HMR_022704-rand.fasta]
  • pleiotrophin [Rattus norvegicus]gi|6679543|ref|NP_032999.1| pleiotrophin [Mus musculus]gi|38197285|gb|AAH61695.1| Pleiotrophin [Mus musculus]gi|12805211|gb|AAH02064.1| Pleiotrophin [Mus musculus]gi|38304038|gb|AAH62013.1| Pleiotrophin [Rattus norvegic [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 Pleiotrophin precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • (NM_017066) pleiotrophin (Heparine binding factor, Hbnf, in the mouse) [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • pleiotrophin [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Pleiotrophin precursor (PTN) (Heparin-binding growth-associated molecule) (HB-GAM) (Heparin-binding growth factor 8) (HBGF-8) (Osteoblast-specific factor 1) (OSF-1) (Heparin-binding neutrophic factor) (HBNF) (Heparin-binding brain mitogen) (HBBM) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • pleiotrophin, isoform CRA_b [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Pleiotrophin [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • heparin-binding growth associated molecule [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 PLEIOTROPHIN PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10116 Gene_Symbol=Ptn Pleiotrophin [rat-ipi-250309-contam.fasta]
  • Pleiotrophin OS=Rattus norvegicus GN=Ptn [011711_HMR.fasta]
    • Organism: Rattus norvegicus
    Length: 168 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [UNKNOWN][IEA]
    extracellular region [IEA]
    Biological Process: bone mineralization [UNKNOWN][IEA]
    positive regulation of cell division [IEA]
    ossification [UNKNOWN]
    learning [UNKNOWN][IEA]
    Molecular Function: growth factor activity [IEA]
    heparin binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSQQYQQQR RKFAAAFLAL IFILAAVDTA EAGKKEKPEK KVKKSDCGEW QWSVCVPTSG  60
   61 DCGLGTREGT RTGAECKQTM KTQRCKIPCN WKKQFGAECK YQFQAWGECD LNTALKTRTG 120
  121 SLKRALHNAD CQKTVTISKP CGKLTKPKPQ AESKKKKKEG KKQEKMLD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..96] PSI-BLAST 19.0 Midkine, a heparin-binding growth factor, N-terminal domain
    2 View Details [97..168] Pfam 32.677781 No description for PF01091.9 was found. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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