Protein Overview: MK09_RAT

General Information:
Name(s) found:	MK09_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|8394233\|ref\|NP_059018.1\| mitogen-activated protein kinase 9 [Rattus norvegicus] [NCBI NR] gi\|743106\|prf\|\|2011373B stress-activated protein kinase SAPK:SUBUNIT=alpha II [NCBI NR] gi\|493209\|gb\|AAA42109.1\| stress activated protein kinase [NCBI NR] gi\|149052424\|gb\|EDM04241.1\| mitogen-activated protein kinase 9, isoform CRA_b [Rattus norvegicus] [NCBI NR] gi\|149052421\|gb\|EDM04238.1\| mitogen-activated protein kinase 9, isoform CRA_b [Rattus norvegicus] [NCBI NR] gi\|1346338\|sp\|P49186.1\|MK09_RAT RecName: Full=Mitogen-activated protein kinase 9; AltName: Full=Stress-activated protein kinase JNK2; AltName: Full=c-Jun N-terminal kinase 2; AltName: Full=SAPK-alpha; AltName: Full=p54-alpha [NCBI NR] Mitogen-activated protein kinase 9 OS=Rattus norvegicus GN=Mapk9 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):10-33432528;10-33432528 Splice isoform Alpha-2 of P49186 [hmr_yeast5_DM3-1_pombe.fasta] stress activated protein kinase alpha II [HMR_022704-rand.fasta] stress activated protein kinase alpha II [Rattus norvegicus]gi\|20306844\|gb\|AAH28341.1\| Mitogen activated protein kinase 9, isoform a [Mus musculus]gi\|4558393\|gb\|AAD22577.1\| protein kinase JNK2 alpha 2 [Mus musculus]gi\|1346338\|sp\|P49186\|MK09_RAT Mitogen [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform Alpha-2 of Mitogen-activated protein kinase 9 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_017322) stress activated protein kinase alpha II [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] mitogen-activated protein kinase 9 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Mitogen-activated protein kinase 9 (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) (SAPK-alpha) (p54-alpha) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] mitogen-activated protein kinase 9, isoform CRA_b [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] stress-activated protein kinase SAPK:SUBUNIT=alpha II [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] stress activated protein kinase [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF MITOGEN-ACTIVATED PROTEIN KINASE 9 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Mapk9 Isoform Alpha-2 of Mitogen-activated protein kinase 9 [rat-ipi-250309-contam.fasta] Isoform Alpha-2 of Mitogen-activated protein kinase 9 OS=Rattus norvegicus GN=Mapk9 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	423 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] cytoplasm [IDA] mitochondrion [IDA] cytosolic part [IDA] nucleoplasm [UNKNOWN]
Biological Process:	response to cytokine stimulus [IEP] positive regulation of nitric oxide biosynthetic process [IMP] positive regulation of transcription [IMP] JNK cascade [UNKNOWN][IDA] protein amino acid phosphorylation [IDA][IEA] response to toxin [IEP] JUN phosphorylation [IMP] response to mechanical stimulus [IEP] positive regulation of prostaglandin secretion [IMP] induction of apoptosis in response to chemical stimulus [UNKNOWN] cellular response to UV [IMP] regulation of protein ubiquitination [IMP] positive regulation of chemokine production [IMP] response to protein stimulus [IEP][IMP] response to organic substance [IEP] positive regulation of cell morphogenesis involved in differentiation [IMP] positive regulation of prostaglandin biosynthetic process [IMP] neuron projection development [IMP] response to amine stimulus [IEP] response to cadmium ion [UNKNOWN] regulation of JNK cascade [IMP] protein targeting to mitochondrion [IEP] positive regulation of caspase activity [IMP] central nervous system development [IEP] positive regulation of nitric-oxide synthase 2 biosynthetic process [IMP] positive regulation of gene expression [UNKNOWN] response to drug [IMP] positive regulation of protein amino acid phosphorylation [IMP] positive regulation of apoptosis [IMP] release of cytochrome c from mitochondria [IMP] response to lipopolysaccharide [IEP] positive regulation of macrophage derived foam cell differentiation [UNKNOWN]
Molecular Function:	nucleotide binding [IEA] ATP binding [IDA][IEA] protein binding [UNKNOWN][IDA][IPI] JUN kinase activity [UNKNOWN][IDA][IMP] MAP kinase activity [IEA] protein serine/threonine kinase activity [UNKNOWN][IEA] transferase activity [IEA] mitogen-activated protein kinase kinase kinase binding [IPI] caspase activator activity [IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDSKSDGQF YSVQVADSTF TVLKRYQQLK PIGSGAQGIV CAAFDTVLGI NVAVKKLSRP  60
   61 FQNQTHAKRA YRELVLLKCV NHKNIISLLN VFTPQKTLEE FQDVYLVMEL MDANLCQVIH 120
  121 MELDHERMSY LLYQMLCGIK HLHSAGIIHR DLKPSNIVVK SDCTLKILDF GLARTACTNF 180
  181 MMTPYVVTRY YRAPEVILGM GYKENVDIWS VGCIMGELVK GCVIFQGTDH IDQWNKVIEQ 240
  241 LGTPSAEFMK KLQPTVRNYV ENRPKYPGIK FEELFPDWIF PSESERDKIK TSQARDLLSK 300
  301 MLVIDPDKRI SVDEALRHPY ITVWYDPAEA EAPPPQIYDA QLEEREHAIE EWKELIYKEV 360
  361 MDWEERSKNG VKDQPSDAAV SSKATPSQSS SINDISSMST EHTLASDTDS SLDASTGPLE 420
  421 GCR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.84

Protein Overview: MK09_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: