General Information: |
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Name(s) found: |
SMAD7_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 426 amino acids |
Gene Ontology: |
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Cellular Component: |
nucleus
[UNKNOWN][IEA]
transcription factor complex [IEA] cytoplasm [UNKNOWN][IEA] cell-cell adherens junction [UNKNOWN][IEA] cytosol [UNKNOWN] catenin complex [UNKNOWN][IEA] intracellular [IEA] plasma membrane [UNKNOWN][IEA] |
Biological Process: |
ventricular cardiac muscle tissue morphogenesis
[IEA]
positive regulation of cell-cell adhesion [UNKNOWN][IEA] transforming growth factor beta receptor signaling pathway [UNKNOWN] negative regulation of ubiquitin-protein ligase activity [UNKNOWN][IEA] regulation of activin receptor signaling pathway [UNKNOWN][IEA] cellular protein complex localization [UNKNOWN][IEA] BMP signaling pathway [UNKNOWN] positive regulation of protein ubiquitination [UNKNOWN][IEA] negative regulation of peptidyl-serine phosphorylation [UNKNOWN][IEA] negative regulation of protein ubiquitination [UNKNOWN] negative regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN][IEA] negative regulation of pathway-restricted SMAD protein phosphorylation [UNKNOWN] regulation of transcription, DNA-dependent [IEA] artery morphogenesis [IEA] negative regulation of transcription factor activity [UNKNOWN][IEA] ventricular septum morphogenesis [IEA] negative regulation of BMP signaling pathway [UNKNOWN][IEA] intracellular signaling pathway [IDA] response to laminar fluid shear stress [UNKNOWN][IEA] ureteric bud development [UNKNOWN][IEA] negative regulation of peptidyl-threonine phosphorylation [UNKNOWN][IEA] negative regulation of transcription by competitive promoter binding [UNKNOWN][IEA] negative regulation of transcription [IEP] adherens junction assembly [UNKNOWN][IEA] regulation of transforming growth factor beta receptor signaling pathway [IDA] positive regulation of proteasomal ubiquitin-dependent protein catabolic process [UNKNOWN][IEA] protein stabilization [UNKNOWN][IEA] negative regulation of transforming growth factor beta receptor signaling pathway [UNKNOWN][IEA] |
Molecular Function: |
transcription factor activity
[IEA]
protein binding [UNKNOWN][IPI] ubiquitin protein ligase binding [UNKNOWN][IPI] activin binding [UNKNOWN][IEA] collagen binding [UNKNOWN][IEA] transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity [UNKNOWN][IEA] beta-catenin binding [UNKNOWN][IEA] promoter binding [UNKNOWN][IEA] I-SMAD binding [UNKNOWN][IEA] type I transforming growth factor beta receptor binding [UNKNOWN][IEA] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MFRTKRSALV RRLWRSRAPG GEDEEEGVGG GGGGGGLRGE GATDGRAYGA GGGGAGRAGC 60 61 CLGKAVRGAK GHHHPHPPSS GAGAAGGAEA DLKALTHSVL KKLKERQLEL LLQAVESRGG 120 121 TRTACLLLPG RLDCRLGPGA PASAQPAQPP SSYSLPLLLC KVFRWPDLRH SSEVKRLCCC 180 181 ESYGKINPEL VCCNPHHLSR LCELESPPPP YSRYPMDFLK PTADCPDAVP SSDETGGTNY 240 241 LAPGGLSDSQ LLLEPGDRSH WCVVAYWEEK TRVGRLYCVQ EPSLDIFYDL PQGNGFCLGQ 300 301 LNSDNKSQLV QKVRSKIGCG IQLTREVDGV WVYNRSSYPI FIKSATLDNP DSRTLLVHKV 360 361 FPGFSIKAFD YEKAYSLQRP NDHEFMQQPW TGFTVQISFV KGWGQCYTRQ FISSCPCWLE 420 421 VIFNSR |
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Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.98 |
Source: Reynolds et al. (2008)