Protein Overview: PTGIS_RAT

General Information:
Name(s) found:	PTGIS_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|38197361\|gb\|AAH61814.1\| Prostaglandin I2 (prostacyclin) synthase [Rattus norvegicus] [NCBI NR] gi\|13928752\|ref\|NP_113745.1\| prostaglandin I2 (prostacyclin) synthase [Rattus norvegicus] [NCBI NR] gi\|1373209\|gb\|AAB02322.1\| prostacyclin synthase [Rattus norvegicus] [NCBI NR] gi\|11387013\|sp\|Q62969.1\|PTGIS_RAT RecName: Full=Prostacyclin synthase; AltName: Full=Prostaglandin I2 synthase [NCBI NR] (Q62969) Prostacyclin synthase (EC 5.3.99.4) (Prostaglandin I2 synthase) [Swiss-Prot] Prostacyclin synthase OS=Rattus norvegicus GN=Ptgis PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):3-151545731;3-151577830 Prostacyclin synthase [hmr_yeast5_DM3-1_pombe.fasta] prostaglandin I2 synthase; Prostaglandin I2 (prostacyclin) synthase [HMR_022704-rand.fasta] prostaglandin I2 synthase [Rattus norvegicus]gi\|38197361\|gb\|AAH61814.1\| Prostaglandin I2 synthase [Rattus norvegicus]gi\|11387013\|sp\|Q62969\|PTGI_RAT Prostacyclin synthase (Prostaglandin I2 synthase)gi\|1373209\|gb\|AAB02322.1\| prostacyclin synthase [Rattus [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Prostacyclin synthase [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_031557) prostaglandin I2 (prostacyclin) synthase [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Prostacyclin synthase (Prostaglandin I2 synthase) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] prostaglandin I2 synthase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Prostaglandin I2 (prostacyclin) synthase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] prostacyclin synthase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 PROSTACYCLIN SYNTHASE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] prostaglandin I2 (prostacyclin) synthase [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Ptgis Prostacyclin synthase [rat-ipi-250309-contam.fasta] Prostacyclin synthase OS=Rattus norvegicus GN=Ptgis [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	501 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum membrane [IEA] endoplasmic reticulum lumen [UNKNOWN] extracellular space [IDA] membrane [IEA] integral to membrane [IEA] endoplasmic reticulum [IEA]
Biological Process:	response to hypoxia [IMP] prostaglandin biosynthetic process [IDA][TAS] fatty acid biosynthetic process [IEA]
Molecular Function:	metal ion binding [IEA] electron carrier activity [IEA] monooxygenase activity [IEA] prostaglandin-I synthase activity [UNKNOWN][IDA][IMP] isomerase activity [IEA] heme binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSWAALLGLL AVLLLLLLLL SRRRARRPGE PPLDLGSIPW LGHALEFGKD AASFLTRMKE  60
   61 KHGDIFTVLV GGRYVTVLLD PHSYDTVVWD LRTRLDFHPY AIFLMERIFD LQLPNFNPSE 120
  121 EKARMKPTLM HKDLQALTEA MYTNLRTVLL GDSTEGGSGW QEKGLLEFSY SSLLSAGYLT 180
  181 LYGVEASPRT HESQALDRDH SADVFRTFRQ LDLMLPKLAR GSLSVGDKDH ACSVKSRLWK 240
  241 LLSPAGLASR ADRSSWLESY LRHLEEMGVS EDMQARALVL QLWATQGNMG PTAFWLLLFL 300
  301 LKNPEALDAV HAELKRIVWQ AEKPVLQMTA LPQKILDSMP VLDSVLNETL RLTAAPFITR 360
  361 EVMADLALPM ADRREFSLRR GDRLLLFPFL SPQKDPEIYT EPEVFKYNRF LNPDGSEKKD 420
  421 FYKDGKRLKN YNMPWGAGHN QCLGKSYAIN SIKQFVVLLL THFDLELVSE DTEVPEFDLS 480
  481 RYGFGLMQPE EDVPIRYRTR L

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: PTGIS_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: