Protein Overview: PDX1_RAT

General Information:
Name(s) found:	PDX1_RAT [Swiss-Prot]
Description(s) found: Found 15 descriptions. SHOW ALL	Pancreas/duodenum homeobox protein 1 OS=Rattus norvegicus GN=Pdx1 PE=1 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	283 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IDA] cytoplasm [IDA] intracellular part [UNKNOWN]
Biological Process:	response to cytokine stimulus [IEP] insulin secretion [UNKNOWN] negative regulation of cell proliferation [UNKNOWN] response to iron(II) ion [IEP] organ senescence [IEP] positive regulation of cell proliferation [UNKNOWN][IMP] response to wounding [IEP] transcription from RNA polymerase II promoter [IDA][IMP] positive regulation of transcription [IMP] protein heterooligomerization [IDA] response to leucine [IEP] positive regulation of DNA binding [IMP] glucose metabolic process [UNKNOWN] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][IDA] negative regulation of transcription from RNA polymerase II promoter [UNKNOWN] response to glucose stimulus [IEP][IMP] stem cell differentiation [IEP][IMP] response to glucocorticoid stimulus [IEP] transdifferentiation [IEP] morphogenesis of embryonic epithelium [UNKNOWN] response to lipid [IEP] response to fatty acid [IEP] positive regulation of insulin secretion [IMP] exocrine pancreas development [UNKNOWN] response to protein stimulus [IEP] endocrine pancreas development [UNKNOWN] response to chlorate [IEP] pancreas development [UNKNOWN][IEP] nitric oxide mediated signal transduction [UNKNOWN] transcription, DNA-dependent [IMP] response to vitamin [IEP] regulation of transcription, DNA-dependent [UNKNOWN][TAS] smoothened signaling pathway [IMP] response to alkaloid [IEP] response to organic cyclic substance [IEP] response to nicotine [IEP] regulation of cell proliferation [UNKNOWN] regulation of transcription from RNA polymerase II promoter [UNKNOWN] central nervous system development [IEP] negative regulation of transcription [IMP] response to drug [IEP] glucose homeostasis [UNKNOWN][IMP] cell differentiation [UNKNOWN][IMP] positive regulation of cell death [IMP] organ regeneration [IEP] response to nutrient levels [IEP]
Molecular Function:	DNA binding [UNKNOWN] transcription factor activity [UNKNOWN][IDA][IMP][TAS] protein binding [UNKNOWN][IPI] protein homodimerization activity [IDA] RNA polymerase II transcription factor activity [UNKNOWN] protein heterodimerization activity [IDA] sequence-specific DNA binding [UNKNOWN][IDA] transcription factor binding [IPI] promoter binding [IDA] transcription activator activity [UNKNOWN][IDA] protein complex binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSEEQYYAA TQLYKDPCAF QRGPVPEFSA NPPACLYMGR QPPPPPPPQF AGSLGTLEQG  60
   61 SPPDISPYEV PPLADDPAGA HLHHHLPAQL GLAHPPPGPF PNGTETGGLE EPSRVHLPFP 120
  121 WMKSTKAHAW KSQWAGGAYA AEPEENKRTR TAYTRAQLLE LEKEFLFNKY ISRPRRVELA 180
  181 VMLNLTERHI KIWFQNRRMK WKKEEDKKRS SGTTSGGGGG EEPEQDCAVT SGEELLALPP 240
  241 PPPPGGAVPS GVPAAAREGR LPSGLSASPQ PSSIAPLRPQ EPR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: PDX1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: