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Protein Overview: ANFC_RAT

General Information:
Name(s) found: ANFC_RAT [Swiss-Prot]
Description(s) found:
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  • gi|227347|prf||1702229A C type natriuretic peptide [NCBI NR]
  • gi|220712|dbj|BAA14250.1| C-type natriuretic peptide [Rattus norvegicus] [NCBI NR]
  • gi|1703305|sp|P55207.1|ANFC_RAT RecName: Full=C-type natriuretic peptide; Contains: RecName: Full=CNP-22; Contains: RecName: Full=CNP-29; Contains: RecName: Full=CNP-53; Flags: Precursor [NCBI NR]
  • gi|16758582|ref|NP_446202.1| natriuretic peptide precursor C [Rattus norvegicus] [NCBI NR]
  • gi|149016359|gb|EDL75605.1| natriuretic peptide precursor type C [Rattus norvegicus] [NCBI NR]
  • pir||S12988 brain natriuretic peptide type C - rat [NCBI NR]
  • C-type natriuretic peptide OS=Rattus norvegicus GN=Nppc PE=2 SV=1 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):9-94319403 C-type natriuretic peptide precursor [Contains: CNP-22; CNP-29; CNP-53] [hmr_yeast5_DM3-1_pombe.fasta]
  • natriuretic peptide precursor C [HMR_022704-rand.fasta]
  • natriuretic peptide precursor C [Rattus norvegicus]gi|220712|dbj|BAA14250.1| C-type natriuretic peptide [Rattus norvegicus]gi|111420|pir||S12988 brain natriuretic peptide type C - ratgi|1703305|sp|P55207|ANFC_RAT C-type natriuretic peptide precursor [C [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 C-type natriuretic peptide precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • (NM_053750) natriuretic peptide precursor C [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • C-type natriuretic peptide precursor [Contains: CNP-22; CNP-29; CNP-53] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • natriuretic peptide precursor type C [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • C-type natriuretic peptide [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • C type natriuretic peptide [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 C-TYPE NATRIURETIC PEPTIDE PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • natriuretic peptide precursor C [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta]
  • Tax_Id=10116 Gene_Symbol=Nppc C-type natriuretic peptide [rat-ipi-250309-contam.fasta]
  • natriuretic peptide precursor C precursor [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • C-type natriuretic peptide OS=Rattus norvegicus GN=Nppc [011711_HMR.fasta]
    • Organism: Rattus norvegicus
    Length: 126 amino acids

    Gene Ontology:
    Cellular Component: extracellular space [IDA]
    extracellular region [IEA]
    Biological Process: cGMP biosynthetic process [UNKNOWN][IDA]
    regulation of multicellular organism growth [UNKNOWN][IEA]
    positive regulation of vasodilation [IDA]
    negative regulation of cell proliferation [IDA]
    post-embryonic development [UNKNOWN][IEA]
    receptor guanylyl cyclase signaling pathway [UNKNOWN][ISS]
    organ development [UNKNOWN][IEA]
    positive regulation of osteoblast differentiation [IDA]
    response to ethanol [IEP]
    regulation of smooth muscle cell proliferation [IEP]
    response to hypoxia [IEP]
    ossification [IEA]
    regulation of blood vessel size [IEA]
    growth plate cartilage chondrocyte differentiation [ISS]
    positive regulation of cGMP biosynthetic process [IDA]
    response to drug [IEP]
    negative regulation of DNA metabolic process [IDA]
    growth plate cartilage chondrocyte proliferation [ISS]
    Molecular Function: protein homodimerization activity [IMP]
    peptide hormone receptor binding [IDA]
    receptor binding [UNKNOWN]
    hormone activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHLSQLIACA LLLALLSLRP SEAKPGTPPK VPRTPPGEEL AEPQAAGGNQ KKGDKTPGGG  60
   61 GANLKGDRSR LLRDLRVDTK SRAAWARLLH EHPNARKYKG GNKKGLSKGC FGLKLDRIGS 120
  121 MSGLGC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..126] Pfam 32.173925 No description for PF00212.9 was found. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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