Protein Overview: ush-PA

General Information:
Name(s) found:	ush-PA / FBpp0077723 [FlyBase]
Description(s) found: Found 22 descriptions. SHOW ALL	The gene u-shaped is referred to in FlyBase by the symbol Dmel\ush (CG2762, FBgn0003963). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:523467..540541. It has the cytological map location 21E1-21E2. There is experimental evidence that it has the molecular function</span>: protein binding; transcription factor binding; transcription regulator activity. There is experimental evidence that it is involved in the biological process</span>: torso signaling pathway; terminal region determination; amnioserosa maintenance; heart development; compound eye development; germ-band shortening; regulation of gene-specific transcription; lymph gland development. 32 alleles are reported. The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: organ system; adult segment; peripheral nervous system; cephalopharyngeal skeleton; adult mesothoracic segment; nervous system; external compound sense organ; cuticle; extended germ band embryo; pharyngeal sclerite. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	1191 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA][NAS]
Biological Process:	dorsal closure [TAS] torso signaling pathway [IGI] germ-band shortening [IMP][TAS] terminal region determination [IGI] regulation of gene-specific transcription [IDA] dorsal closure, leading edge cell fate determination [NAS] hemopoiesis [TAS] head involution [NAS] pigment metabolic process [TAS] negative regulation of cell fate specification [TAS] amnioserosa maintenance [IMP][TAS] ectoderm development [TAS] regulation of transcription [NAS] compound eye development [IMP] heart development [IMP][TAS] negative regulation of crystal cell differentiation [TAS] lymph gland development [IMP]
Molecular Function:	transcription factor activity [NAS] zinc ion binding [IEA] protein binding [IPI] transcription regulator activity [IDA] ligand-dependent nuclear receptor activity [NAS] transcription factor binding [IMP][TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSSNTRGDC SDTAEEMTVD SRDSKDLSAQ DIGEQKQQQM EDQLEDQLND SRDPQNNNNN  60
   61 IDDDADEDAE FEEPEKANPQ QDQDLGETEM EQEHDLQQED LQQELPANSP STPPRSPSSP 120
  121 QLIPKLEQPA TPPSEPEASP CPSPSPCPTP KYPKVRLNAL LASDPALKPD AKELTLPDSR 180
  181 LLAPPPLVKP DTQAQPEVAE PLLKPARFMC LPCGIAFSSP STLEAHQAYY CSHRIKDTDE 240
  241 AGSDKSGAGG SGATAGDAAG LTGGSTEPPA KMARTGKQYG CTQCSYSADK KVSLNRHMRM 300
  301 HQTSPAAPTL AGLPSLLQNG IAPPGVTPNP MEDSSSQQTD RYCSHCDIRF NNIKTYRAHK 360
  361 QHYCSSRRPE GQLTPKPDAS PGAGSGPGSA GGSIGVSAQA ATPGKLSPQA RNKTPTPAMV 420
  421 AVAAAAAAAA ASLQATPHSH PPFLALPTHP IIIVPCSLIR AASFIPGPLP TPNSGIVNPE 480
  481 TTCFTVDNGT IKPLATALVG ATLEPERPSA PSSAAEATEA KSSPPEPKRK EAGLTRESAP 540
  541 LDLSLRRSPI TLNSLSLRQR QLRNALLDVE EVLLAGVGTG KENVETPRGG GSVTPEQIVC 600
  601 APSLPSSPSM SPSPKRRAIS PRSSGAGSAS SMSPPGLNVA VPHLLDMRSM LPADFGLSES 660
  661 LLAKTNPELA LKLAAAAAAA AVAGSSGAAA FPPASLPAQT SSGNPGSGGS AGGAQQPQIY 720
  721 VKKGVSKCME CNIVFCKYEN YLAHKQHYCS ARSQEGASEV DVKSAVSPSI AGAGGLGAGA 780
  781 AEAASSVETT PVAYQQLICA ACGIKYTSLD NLRAHQNYYC PKGGAVAAPA ATPTDPGQLG 840
  841 MPKEKCGKCK TLHEIGLPCP PPVANPLAAP TVNPQPATNS LNKCPVCGVV SPTAALAKKH 900
  901 MEMHGTVKAY RCSICQYKGN TLRGMRTHIR THFDKKTSDV NEELYMTCIF EEDASALSQE 960
  961 LVTPTGASTT TGHDSMDHPS QMFNCDYCNY VSTYKGNVLR HMKLMHPHVA INSPSISPDT1020
 1021 RDQDVTSNPT TNQHSNSDVS NGEAPSFHIK SEPLDPPPTV NLVHENNNSP IATPHIKAEP1080
 1081 IEVGADAAPG GLVPPMTSPL GNSSSVAAAA AAAAEVMKKY CSTCDISFNY VKTYLAHKQF1140
 1141 YCKNKPIRPE ASDSPSPNHL GGGVAVGLGI GGLVGGHGQQ KNKENLQEAA I

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.22

Protein Overview: ush-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: