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Protein Overview: p38b-PA

General Information:
Name(s) found: p38b-PA / FBpp0080111 [FlyBase]
Description(s) found:
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  • gi|7298087|gb|AAF53326.1| p38b [Drosophila melanogaster] [NCBI NR]
  • gb|AAF44812.1| symbol=p38b; synonym=BG:DS00797.3; cDNA=method:''sim4'', score:''1000.0'', desc:''GM01004 GM Drosophila melanogaster ovary BlueScript Drosophila melanogaster cDNA clone, full length mRNA sequence from BDGP''; cDNA=method:''sim4'', score:''9 [NCBI NR]
  • gi|4038644|dbj|BAA35141.1| p38 MAP kinase [Drosophila melanogaster] [NCBI NR]
  • gi|3158384|gb|AAC39032.1| stress-activated p38b MAP kinase [Drosophila melanogaster] [NCBI NR]
  • gi|20455044|sp|O61443.1|MK14B_DROME RecName: Full=Mitogen-activated protein kinase 14B; AltName: Full=MAP kinase p38b; Short=D-p38b [NCBI NR]
  • gi|17137550|ref|NP_477361.1| p38b [Drosophila melanogaster] [NCBI NR]
  • gi|16198005|gb|AAL13777.1| LD24658p [Drosophila melanogaster] [NCBI NR]
  • Mitogen-activated protein kinase 14B OS=Drosophila melanogaster GN=p38b PE=1 SV=1 [Swiss-Prot]
  • (O61443) Mitogen-activated protein kinase 14B (EC 2.7.1.37) (MAP kinase p38b) (D-p38b) [Swiss-Prot]
  • The gene p38b is referred to in FlyBase by the symbol Dmel\p38b (CG7393, FBgn0024846). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:13780695..13782611. It has the cytological map location 34D1. There is experimental evidence that it has the molecular function</span>: protein serine/threonine kinase activity. There is experimental evidence that it is involved in the biological process</span>: immune response; transforming growth factor beta receptor signaling pathway; regulation of BMP signaling pathway; response to salt stress; MAPKKK cascade; regulation of innate immune response; imaginal disc-derived wing morphogenesis; response to stress. 9 alleles are reported. The phenotypes of these alleles are annotated with: wing; wing vein. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG7393-PA translation from_gene[CG7393 p38b FBgn0024846] seq_release:3 mol_weight=42099 cds_boundaries:(2L:13,763,152..13,764,246[+]) aa_length:365 transcript_info:[CG7393-RA seq_release:3] gene_info:[gene symbol:p38b FBgn0024846 gene_boundaries:(2L:1 [hmr_yeast5_DM3-1_pombe.fasta]
  • (AE003641) p38b gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG7393-PA [Drosophila melanogaster]gi|7287774|gb|AAF44812.1| symbol=p38b; synonym=BG:DS00797.3; cDNA=method:''sim4'', score:''1000.0'', desc:''GM01004 GM Drosophila melanogaster ovary BlueScript Drosophila melanogaster cDNA clone, full length mRNA sequen [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2L:13781000..13782097; ID=FBpp0080111; name=p38b-PA; parent=FBgn0024846,FBtr0080534; dbxref=GB_protein:AAF53326.1,FlyBase:FBpp0080111,FlyBase_Annotation_IDs:CG7393-PA,REFSEQ:NP_477361,GB_protein:AAF53326; MD5=394eea644f87619a1b7e2a4e8cb6 [fly-100309-contam.fasta]
  • Mitogen-activated protein kinase 14B (MAP kinase p38b) (D-p38b) [nr-271106-contam.fasta]
  • CG7393-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • LD24658p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • p38 MAP kinase [Drosophila melanogaster] [nr-271106-contam.fasta]
  • stress-activated p38b MAP kinase [Drosophila melanogaster] [nr-271106-contam.fasta]
  • p38b CG7393-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2L:13781000..13782097; ID=FBpp0080111; name=p38b-PA; parent=FBgn0024846,FBtr0080534; dbxref=GB_protein:AAF53326.1,FlyBase:FBpp0080111,FlyBase_Annotation_IDs:CG7393-PA,REFSEQ:NP_477361,GB_protein:AAF53326; MD5=394eea644f87619a1b7e2a4e8cb6e8da; length=365; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2L:13781000..13782097; ID=FBpp0080111; name=p38b-PA; parent=FBgn0024846,FBtr0080534; dbxref=GB_protein:AAF53326.1,FlyBase:FBpp0080111,FlyBase_Annotation_IDs:CG7393-PA,REFSEQ:NP_477361,GB_protein:AAF53326; MD5=394eea644f87619a1b7e2a4e8cb6e8da; length=365; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=2L:13781000..13782097; ID=FBpp0080111; name=p38b-PA; parent=FBgn0024846,FBtr0080534; dbxref=GB_protein:AAF53326.1,FlyBase:FBpp0080111,FlyBase_Annotation_IDs:CG7393-PA,REFSEQ:NP_477361,GB_protein:AAF53326,FlyMine:FBpp0080111,modMine:FBpp0080111; MD5=394eea644f87619a1b7e2a4e8cb6e8da; length=365; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2L:13781000..13782097; ID=FBpp0080111; name=p38b-PA; parent=FBgn0024846,FBtr0080534; dbxref=GB_protein:AAF53326.1,FlyBase:FBpp0080111,FlyBase_Annotation_IDs:CG7393-PA,REFSEQ:NP_477361,GB_protein:AAF53326,FlyMine:FBpp0080111,modMine:FBpp0080111; MD5=394eea644f87619a1b7e2a4e8cb6e8da; length=365; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2L:13781000..13782097; ID=FBpp0080111; name=p38b-PA; parent=FBgn0024846,FBtr0080534; dbxref=GB_protein:AAF53326.1,FlyBase:FBpp0080111,FlyBase_Annotation_IDs:CG7393-PA,REFSEQ:NP_477361,GB_protein:AAF53326,FlyMine:FBpp0080111,modMine:FBpp0080111; MD5=394eea644f87619a1b7e2a4e8cb6e8da; length=365; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0080111 type=protein; loc=2L:13781000..13782097; ID=FBpp0080111; name=p38b-PA; parent=FBgn0024846,FBtr0080534; dbxref=GB_protein:AAF53326.1,FlyBase:FBpp0080111,FlyBase_Annotation_IDs:CG7393-PA,REFSEQ:NP_477361,GB_protein:AAF53326,FlyMine:FBpp0080111,modMine:FBpp0080111; MD5=394eea644f87619a1b7e2a4e8cb6e8da; length=365; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2L:13781000..13782097; ID=FBpp0080111; name=p38b-PA; parent=FBgn0024846,FBtr0080534; dbxref=GB_protein:AAF53326.1,FlyBase:FBpp0080111,FlyBase_Annotation_IDs:CG7393-PA,REFSEQ:NP_477361,GB_protein:AAF53326,UniProt/Swiss-Prot:O61443,FlyMine:FBpp0080111,modMine:FBpp0080111; MD5=394eea644f87619a1b7e2a4e8cb6e8da; length=365; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 365 amino acids

    Gene Ontology:
    Cellular Component: nucleus [NAS]
    Biological Process: MAPKKK cascade [IDA][NAS]
    immune response [IMP]
    response to salt stress [IGI]
    regulation of innate immune response [IDA]
    imaginal disc-derived wing morphogenesis [IDA]
    transforming growth factor beta receptor signaling pathway [IGI]
    regulation of BMP signaling pathway [IDA]
    protein amino acid phosphorylation [IEA][NAS]
    defense response [NAS]
    response to stress [IDA]
    Molecular Function: ATP binding [IEA]
    MAP kinase activity [ISS][NAS]
    SAP kinase activity [NAS]
    protein serine/threonine kinase activity [IDA][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRKMAKFYK LDINRTEWEI PETYQNLQPV GQGAYGQVCK AVVRGTSTKV AIKKLARPFQ  60
   61 SAVHAKRTYR ELRLLKHMDH ENVIGLLDVF HPGQPADSLD QFQQVYMVTH LMDADLNNII 120
  121 RTQKLSDDHV QFLVYQILRG LKYIHSAGVI HRDLKPSNIA VNEDCELRIL DFGLARPAES 180
  181 EMTGYVATRW YRAPEIMLNW MHYNQTADIW SVGCIMAELL TGRTLFPGTD HIHQLNLIME 240
  241 VLGTPADEFM SRISSESARN YIRSLPVMPR RNFRDIFRGA NPLAIDLLEK MLELDADKRI 300
  301 TAEQALAHPY MEKYHDPTDE QTAALYDQSF EENELPVEKW REMVFSEVTA FKPTAAFAEL 360
  361 LPKEQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle