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Protein Overview: FBpp0302919, NaP...

General Information:
Name(s) found: FBpp0302919 [FlyBase]
NaPi-T-PA / FBpp0086593 [FlyBase]
Description(s) found:
Found 29 descriptions.
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  • type=protein; loc=2R:complement(10730873..10731148,10731213..10731454,10731526..10731658,10731718..10732170,10732225..10732470,10732587..10732801,10732933..10732942); ID=FBpp0302919; name=NaPi-T-PB; parent=FBgn0016684,FBtr0329884; dbxref=FlyBase:FBpp0302919,FlyBase_Annotation_IDs:CG10207-PB,REFSEQ:NP_001260981,GB_protein:AGB93513; MD5=cfe54bccdbbe9f95b1e5d764621e4424; length=524; release=r5.56; species=Dmel; [FlyBase]
  • The gene Na<sup>+</sup>-dependent inorganic phosphate cotransporter is referred to in FlyBase by the symbol Dmel\NaPi-T (CG10207, FBgn0016684). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:10730216..10733379. It has the cytological map location 51C5. Based on sequence similarity, it is predicted to have molecular function</span>: high affinity inorganic phosphate:sodium symporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: transmembrane transport; phosphate transport. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 524 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEA]
    Biological Process: transmembrane transport [IEA]
    phosphate transport [IEA]
    Molecular Function: high affinity inorganic phosphate:sodium symporter activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGQVEARTVL WYMTFIGFIV NYMIRINLNI TIVDMIAGKG AITSNETHEN STDLAALAEM  60
   61 NERFSLERWF LDWANIPYEK NGFHWNEKQQ GALLGSFFWA HWTLQIPGGI LATKYGTKLV 120
  121 FGWSNGIGVF CCFLIPIVSY WSYTGLIILR VFQGWITGLA WPSMHVLTAK WIPPNERSKF 180
  181 VSAYLGSSVG VALFYPIFGY IIDWTRWEWV YYICGIVGTL WFIAWQFLVF DSPAEHPRIA 240
  241 DSERKFIEKS LGASIQGSKG PTPWKAIATS RPVWLNVVAQ WGGIWGLFTL MTHAPTYFRL 300
  301 IHHWNIRATG FLSGLPHLMR MLFAYVFSIF ADYLLRTDKM SRTNVRKLAT FICCGTKGLI 360
  361 VLALAYFGYN ATAAIVLVTV ATMLHGAVSS GPLASMVDLS PNYAGIVLGV SGMIGGMPGF 420
  421 ISPFIVGQLT HNNQTIDAWK NVFLLTSLML TGSGILYVLF SESKLQPWNS GCHQLPDSGL 480
  481 KELQNLGRDQ DDEEEKKPLK SDHDKETPIV AEQETKTKSD CDEK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..524] PSI-BLAST 45.69897 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • substrate-specific transmembrane transporter activity
    		•  5.46247398538901 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.58978526526921 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.31967711223954 bayes_pls_golite062009
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  3.94605227012838 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  2.52916479889426 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  2.15783210522667 bayes_pls_golite062009
  • phosphate transmembrane transporter activity
    		•  1.78662033436109 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • binding
    		•  1.26757615356623 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  0.143419068761182 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  0.143419068761182 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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