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Protein Overview: Flo-PA

General Information:
Name(s) found: Flo-PA / FBpp0086484 [FlyBase]
Description(s) found:
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  • gi|7303052|gb|AAF58120.1| flotillin, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|3115385|gb|AAC39012.1| flotillin-1 [Drosophila melanogaster] [NCBI NR]
  • gi|17137546|ref|NP_477358.1| flotillin, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|16186251|gb|AAL14023.1| SD10657p [Drosophila melanogaster] [NCBI NR]
  • gi|13124177|sp|O61491.1|FLOT1_DROME RecName: Full=Flotillin-1 [NCBI NR]
  • (O61491) Flotillin-1 [Swiss-Prot]
  • Flotillin-1 OS=Drosophila melanogaster GN=Flo1 PE=2 SV=1 [Swiss-Prot]
  • The gene flotillin is referred to in FlyBase by the symbol Dmel\Flo (CG8200, FBgn0024754). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:11453772..11456907. It has the cytological map location 52A13. There is experimental evidence that it has the molecular function</span>: structural molecule activity. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG8200-PA translation from_gene[CG8200 Flo FBgn0024754] seq_release:3 mol_weight=47136 cds_boundaries:(2R:10,630,302..10,632,895[-]) aa_length:426 transcript_info:[CG8200-RA seq_release:3] gene_info:[gene symbol:Flo FBgn0024754 gene_boundaries:(2R:10, [hmr_yeast5_DM3-1_pombe.fasta]
  • (AE003810) Flo gene product [alt 1] [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG8200-PA, isoform A [Drosophila melanogaster]gi|16186251|gb|AAL14023.1| SD10657p [Drosophila melanogaster]gi|17137546|ref|NP_477358.1| CG8200-PA [Drosophila melanogaster]gi|3115385|gb|AAC39012.1| flotillin-1 [Drosophila melanogaster]gi|13124177|sp|O6 [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:complement(11454079..11454096,11454308..11454472,11454534..11454677,11454748..11455218,11455657..11456011,11456256..11456331,11456624..11456675); ID=FBpp0086484; name=Flo-PA; parent=FBgn0024754,FBtr0087351; dbxref=FlyBase:FBpp0086484, [fly-100309-contam.fasta]
  • Flotillin-1 [nr-271106-contam.fasta]
  • SD10657p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • flotillin-1 [Drosophila melanogaster] [nr-271106-contam.fasta]
  • flotillin CG8200-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG8200-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:complement(11454079..11454096,11454308..11454472,11454534..11454677,11454748..11455218,11455657..11456011,11456256..11456331,11456624..11456675); ID=FBpp0086484; name=Flo-PA; parent=FBgn0024754,FBtr0087351; dbxref=FlyBase:FBpp0086484,FlyBase_Annotation_IDs:CG8200-PA,GB_protein:AAF58120.1,REFSEQ:NP_477358,GB_protein:AAF58120; MD5=64f22fa88d0a669dc69be26fff722cbf; length=426; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:complement(11454079..11454096,11454308..11454472,11454534..11454677,11454748..11455218,11455657..11456011,11456256..11456331,11456624..11456675); ID=FBpp0086484; name=Flo-PA; parent=FBgn0024754,FBtr0087351; dbxref=FlyBase:FBpp0086484,FlyBase_Annotation_IDs:CG8200-PA,GB_protein:AAF58120.1,REFSEQ:NP_477358,GB_protein:AAF58120; MD5=64f22fa88d0a669dc69be26fff722cbf; length=426; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Flotillin-1 OS=Drosophila melanogaster GN=Flo PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:complement(11454079..11454096,11454308..11454472,11454534..11454677,11454748..11455218,11455657..11456011,11456256..11456331,11456624..11456675); ID=FBpp0086484; name=Flo-1-PA; parent=FBgn0024754,FBtr0087351; dbxref=FlyBase:FBpp0086484,FlyBase_Annotation_IDs:CG8200-PA,GB_protein:AAF58120.1,REFSEQ:NP_477358,GB_protein:AAF58120,FlyMine:FBpp0086484,modMine:FBpp0086484; MD5=64f22fa88d0a669dc69be26fff722cbf; length=426; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:complement(join(15569119..15569170,15568751..15568826,15568152..15568506,15567243..15567713,15567029..15567172,15566803..15566967,15566574..15566591)); ID=FBpp0086484; name=Flo1-PA; parent=FBgn0024754,FBtr0087351; dbxref=FlyBase:FBpp0086484,FlyBase_Annotation_IDs:CG8200-PA,GB_protein:AAF58120.1,REFSEQ:NP_477358,GB_protein:AAF58120,FlyMine:FBpp0086484,modMine:FBpp0086484; MD5=64f22fa88d0a669dc69be26fff722cbf; length=426; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:complement(join(15569119..15569170,15568751..15568826,15568152..15568506,15567243..15567713,15567029..15567172,15566803..15566967,15566574..15566591)); ID=FBpp0086484; name=Flo1-PA; parent=FBgn0024754,FBtr0087351; dbxref=FlyBase:FBpp0086484,FlyBase_Annotation_IDs:CG8200-PA,GB_protein:AAF58120.1,REFSEQ:NP_477358,GB_protein:AAF58120,FlyMine:FBpp0086484,modMine:FBpp0086484; MD5=64f22fa88d0a669dc69be26fff722cbf; length=426; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0086484 type=protein; loc=2R:complement(join(15569119..15569170,15568751..15568826,15568152..15568506,15567243..15567713,15567029..15567172,15566803..15566967,15566574..15566591)); ID=FBpp0086484; name=Flo1-PA; parent=FBgn0024754,FBtr0087351; dbxref=FlyBase:FBpp0086484,FlyBase_Annotation_IDs:CG8200-PA,GB_protein:AAF58120.1,REFSEQ:NP_477358,GB_protein:AAF58120,FlyMine:FBpp0086484,modMine:FBpp0086484; MD5=64f22fa88d0a669dc69be26fff722cbf; length=426; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:complement(join(15569119..15569170,15568751..15568826,15568152..15568506,15567243..15567713,15567029..15567172,15566803..15566967,15566574..15566591)); ID=FBpp0086484; name=Flo1-PA; parent=FBgn0024754,FBtr0087351; dbxref=FlyBase:FBpp0086484,FlyBase_Annotation_IDs:CG8200-PA,GB_protein:AAF58120.1,REFSEQ:NP_477358,GB_protein:AAF58120,UniProt/Swiss-Prot:O61491,FlyMine:FBpp0086484,modMine:FBpp0086484; MD5=64f22fa88d0a669dc69be26fff722cbf; length=426; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 426 amino acids

    Gene Ontology:
    Cellular Component: flotillin complex [NAS]
    Biological Process: biological_process [ND]
    Molecular Function: structural molecule activity [IEP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTWGFVTCGP NEALVVSGCC YMKPLLVPGG RAFVWPVGQQ VQRISLNTMT LQVESPCVYT  60
   61 SQGVPISVTG IAQVKVQGQN EDMLLTACEQ FLGKSEAEIN HIALVTLEGH QRAIMGSMTV 120
  121 EEIYKDRKKF SKQVFEVASS DLANMGITVV SYTIKDLRDE EGYLRSLGMA RTAEVKRDAR 180
  181 IGEAEARAEA HIKEAIAEEQ RMAARFLNDT DIAKAQRDFE LKKAAYDVEV QTKKAEAEMA 240
  241 YELQAAKTKQ RIKEEQMQVK VIERTQEIAV QEQEIMRRER ELEATIRRPA EAEKFRMEKL 300
  301 AEANKQRVVM EAEAEAESIR IRGEAEAFAI AAKAKAEAEQ MAMKAEAYRE YREAAMVEML 360
  361 LDTLPKVAAE VAAPLSQAKK ITMVSSGTGD IGAAKLTGEV LSIVNKVPEL VKNITGVDIA 420
  421 RSVHAG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..158] PSI-BLAST 21.045757 Solution Structure of the Band 7 Domain of the mouse Flotillin 2 Protein
    2 View Details [159..426] FFAS03 1.14 Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.23605224291772 bayes_pls_golite062009
  • protein binding
    		•  0.792911224088066 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle