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Protein Overview: CG7375-PA, FBpp0...

General Information:
Name(s) found: FBpp0304449 [FlyBase]
FBpp0304448 [FlyBase]
CG7375-PA / FBpp0076445 [FlyBase]
Description(s) found:
Found 37 descriptions.
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  • type=protein; loc=3L:complement(8189840..8189983,8190242..8190543,8190622..8190721); ID=FBpp0304449; name=Ubc12-PC; parent=FBgn0035853,FBtr0332139; dbxref=FlyBase:FBpp0304449,FlyBase_Annotation_IDs:CG7375-PC,REFSEQ:NP_001261568,GB_protein:AGB94263; MD5=eb29f75ac32e8a44d527f6000d54f5af; length=181; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=3L:complement(8189840..8189983,8190242..8190543,8190622..8190721); ID=FBpp0304448; name=Ubc12-PB; parent=FBgn0035853,FBtr0332138; dbxref=FlyBase:FBpp0304448,FlyBase_Annotation_IDs:CG7375-PB,REFSEQ:NP_001261567,GB_protein:AGB94262; MD5=eb29f75ac32e8a44d527f6000d54f5af; length=181; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG7375 (CG7375, FBgn0035853). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:8189633..8190956. It has the cytological map location 66B12. Based on sequence similarity, it is predicted to have molecular function</span>: ubiquitin-protein ligase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: post-translational protein modification; regulation of protein metabolic process. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 181 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: regulation of protein metabolic process [IEA]
    post-translational protein modification [IEA]
    Molecular Function: ubiquitin-protein ligase activity [ISS]
    ATP binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIKLFTLKQQ KKDGEQKGSQ QKKASAAQLR IQKDINELNL PNTCATDFPD PNDLLNFKLI  60
   61 ISPDEGFYRD GRFVFNFRVG SNYPHEPPKV KCATQVYHPN IDLDGNVCLN ILREDWNPVL 120
  121 NINSIVYGLQ FLFLEPNPED PLNKEAADVL QTNRRQFENN VKKAMRGGCV GETYFECCLL 180
  181 K

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..181] PSI-BLAST 45.39794 No description for 2nvuC was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  11.3486134076304 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  11.2964721480824 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  10.2401422444624 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  8.93602533934698 bayes_pls_golite062009
  • ligase activity
    		•  5.17219147802758 bayes_pls_golite062009
  • ISG15 ligase activity
    		•  3.37361650623694 bayes_pls_golite062009
  • NEDD8 ligase activity
    		•  3.30521803258995 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.21355731489173 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.13970605403492 bayes_pls_golite062009
  • DNA binding
    		•  1.95596447916631 bayes_pls_golite062009
  • protein binding
    		•  1.77678273247394 bayes_pls_golite062009
  • binding
    		•  1.75350658654805 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.5236035191291 bayes_pls_golite062009
  • transcription activator activity
    		•  1.19240180311941 bayes_pls_golite062009
  • catalytic activity
    		•  0.891402822028799 bayes_pls_golite062009
  • SUMO ligase activity
    		•  0.843488104298821 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.58835335751383 bayes_pls_golite062009
  • kinase activity
    		•  0.519703305315987 bayes_pls_golite062009
  • protein kinase activity
    		•  0.443948654247666 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.373779304908933 bayes_pls_golite062009
  • small protein activating enzyme activity
    		•  0.36227294335656 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.182854082413338 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.122859425935324 bayes_pls_golite062009
  • transferase activity
    		•  0.0984525836903841 bayes_pls_golite062009
  • transcription factor binding
    		•  0.0104967529560147 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle