Protein Overview: MTF-1-PA

General Information:
Name(s) found:	MTF-1-PA / FBpp0076187 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|24661613\|ref\|NP_648311.2\| metal response element-binding transcription Factor-1, isoform A [Drosophila melanogaster] [NCBI NR] gi\|23093822\|gb\|AAF50271.2\| metal response element-binding transcription Factor-1, isoform A [Drosophila melanogaster] [NCBI NR] The gene Metal response element-binding Transcription Factor-1 is referred to in FlyBase by the symbol Dmel\MTF-1 (CG3743, FBgn0040305). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:9423442..9431809. It has the cytological map location 67B5-67B6. There is experimental evidence that it has the molecular function</span>: transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: response to copper ion; response to metal ion; cellular metal ion homeostasis. 15 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase] >CG3743-PA translation from_gene[CG3743 MTF-1 FBgn0040305] seq_release:3 mol_weight=85150 cds_boundaries:(3L:9,388,051..9,395,448[+]) aa_length:791 transcript_info:[CG3743-RA seq_release:3] gene_info:[gene symbol:MTF-1 FBgn0040305 gene_boundaries:(3L:9 [hmr_yeast5_DM3-1_pombe.fasta] (Q9VSY7) CG3743 protein [DrosMelano7227.FASTAC.txt] CG3743-PA, isoform A [Drosophila melanogaster]gi\|24661613\|ref\|NP_648311.2\| CG3743-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:join(9423622..9423936,9427496..9427598,9428957..9429107,9429216..9431022); ID=FBpp0076187; name=MTF-1-PA; parent=FBgn0040305,FBtr0076459; dbxref=FlyBase:FBpp0076187,FlyBase_Annotation_IDs:CG3743-PA,GB_protein:AAF50271.2,REFSEQ:NP_6483 [fly-100309-contam.fasta] MTF-1 CG3743-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] CG3743-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:join(9423622..9423936,9427496..9427598,9428957..9429107,9429216..9431022); ID=FBpp0076187; name=MTF-1-PA; parent=FBgn0040305,FBtr0076459; dbxref=FlyBase:FBpp0076187,FlyBase_Annotation_IDs:CG3743-PA,GB_protein:AAF50271.2,REFSEQ:NP_648311,GB_protein:AAF50271; MD5=b7c20b2d8fb63928e134fe1a73ede2e6; length=791; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:join(9423622..9423936,9427496..9427598,9428957..9429107,9429216..9431022); ID=FBpp0076187; name=MTF-1-PA; parent=FBgn0040305,FBtr0076459; dbxref=FlyBase:FBpp0076187,FlyBase_Annotation_IDs:CG3743-PA,GB_protein:AAF50271.2,REFSEQ:NP_648311,GB_protein:AAF50271; MD5=b7c20b2d8fb63928e134fe1a73ede2e6; length=791; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Metal response element-binding transcription Factor-1, isoform A OS=Drosophila melanogaster GN=MTF-1 PE=1 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3L:join(9423622..9423936,9427496..9427598,9428957..9429107,9429216..9431022); ID=FBpp0076187; name=MTF-1-PA; parent=FBgn0040305,FBtr0076459; dbxref=FlyBase:FBpp0076187,FlyBase_Annotation_IDs:CG3743-PA,GB_protein:AAF50271.2,REFSEQ:NP_648311,GB_protein:AAF50271,FlyMine:FBpp0076187,modMine:FBpp0076187; MD5=b7c20b2d8fb63928e134fe1a73ede2e6; length=791; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] Metal response element-binding transcription Factor-1, isoform A OS=Drosophila melanogaster GN=MTF-1 PE=2 SV=2 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta] type=protein; loc=3L:join(9430522..9430836,9434396..9434498,9435857..9436007,9436116..9437922); ID=FBpp0076187; name=MTF-1-PA; parent=FBgn0040305,FBtr0076459; dbxref=FlyBase:FBpp0076187,FlyBase_Annotation_IDs:CG3743-PA,GB_protein:AAF50271.2,REFSEQ:NP_648311,GB_protein:AAF50271,FlyMine:FBpp0076187,modMine:FBpp0076187; MD5=b7c20b2d8fb63928e134fe1a73ede2e6; length=791; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:join(9430522..9430836,9434396..9434498,9435857..9436007,9436116..9437922); ID=FBpp0076187; name=MTF-1-PA; parent=FBgn0040305,FBtr0076459; dbxref=FlyBase:FBpp0076187,FlyBase_Annotation_IDs:CG3743-PA,GB_protein:AAF50271.2,REFSEQ:NP_648311,GB_protein:AAF50271,FlyMine:FBpp0076187,modMine:FBpp0076187; MD5=b7c20b2d8fb63928e134fe1a73ede2e6; length=791; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Isoform of A8JNP3, Metal response element-binding transcription Factor-1, isoform A OS=Drosophila melanogaster GN=MTF-1 PE=1 SV=2 [DROME.fasta.20160308] FBpp0076187 type=protein; loc=3L:join(9430522..9430836,9434396..9434498,9435857..9436007,9436116..9437922); ID=FBpp0076187; name=MTF-1-PA; parent=FBgn0040305,FBtr0076459; dbxref=FlyBase:FBpp0076187,FlyBase_Annotation_IDs:CG3743-PA,GB_protein:AAF50271.2,REFSEQ:NP_648311,GB_protein:AAF50271,FlyMine:FBpp0076187,modMine:FBpp0076187; MD5=b7c20b2d8fb63928e134fe1a73ede2e6; length=791; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:join(9430522..9430836,9434396..9434498,9435857..9436007,9436116..9437922); ID=FBpp0076187; name=MTF-1-PA; parent=FBgn0040305,FBtr0076459; dbxref=FlyBase:FBpp0076187,FlyBase_Annotation_IDs:CG3743-PA,GB_protein:AAF50271.2,REFSEQ:NP_648311,GB_protein:AAF50271,UniProt/TrEMBL:Q9VSY7,FlyMine:FBpp0076187,modMine:FBpp0076187; MD5=b7c20b2d8fb63928e134fe1a73ede2e6; length=791; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	791 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA][NAS] cytoplasm [IDA]
Biological Process:	transcription [NAS] response to copper ion [IMP] response to metal ion [IMP] cellular metal ion homeostasis [IMP]
Molecular Function:	transcription factor activity [IDA][NAS] zinc ion binding [IEA] specific RNA polymerase II transcription factor activity [NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNDQEKQHQQ QQQHYFHSEW KTTANSHGNS LSDSRDYDTN SSRNSLSGSP PVTSNCSSSG  60
   61 SLDFDRPLAQ LLEPKLEADG LGIIHGDNYS IYGSQTAEST SGEQQSSDEA LSRYRCNYEN 120
  121 CYRSYSTIGN LRTHLKTHTG DYSFKCPEDG CHKAFLTSYS LKIHVRVHTK VKPYECEVSG 180
  181 CDKAFNTRYR LHAHLRLHNG ETFNCELCQK CFTTLSDLKK HMRTHTQERP YKCPEDDCGK 240
  241 AFTASHHLKT HRRTHTGEKP YPCQEDSCQK SFSTSHSLKS HKKTHQRQLQ NKGRKKRPLK 300
  301 TQQTKCSDQE QKDPQQEEQE EEEFIKEDQP EMTLLNPGSH CSETTSTDSG VVLQTLTPQD 360
  361 HLSNVFILQG NEPLILPETS QAYQLSYAAE EEIPSPWIDA GVLVSKPIIP MAPLTDACVA 420
  421 LPTEMPSFVN LKPTFGNAVS GNMGDPQPET MDVDPTVETS LPTPTLELNQ PNIEELLKQD 480
  481 SFENEEDMET ESLLNDILMT IDNNSALLQA TLQQASQVPS DASGLVELDI RDNKPTLKQI 540
  541 TADAGICNCT NCKCDQTKSC HGGDCGAAAA QQTTRTGAPT TTTTTTTMNS SGGKRICGSV 600
  601 VPTKKVSKRE TEMNQNIEDV ALLLQNLASM SSGGSSGGGG GCCGGGAVKP APSGGGCCGE 660
  661 PKAPKPVNAG CGCARPSAPS SGGCCGSGVA STPKPTGGCC SGNQKPAPTA TAASSPSCCC 720
  721 SGKGEVQEPP VISSASSAPA AAVKGNACTC KSPAEGVANG CCVVICIKTL QALRKVLTRR 780
  781 NLNLMLCPQQ N

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: MTF-1-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: