Protein Overview: U4-U6-60K-PA

General Information:
Name(s) found:	U4-U6-60K-PA / FBpp0074971 [FlyBase]
Description(s) found: Found 22 descriptions. SHOW ALL	The gene U4-U6 small nuclear riboprotein factor 60K is referred to in FlyBase by the symbol Dmel\U4-U6-60K (CG6322, FBgn0036733). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:17504955..17507011. It has the cytological map location 74D2. There is experimental evidence that it has the molecular function</span>: U4 snRNA binding; U6 snRNA binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: nuclear mRNA splicing, via spliceosome; RNA splicing. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	553 amino acids
Gene Ontology:
Cellular Component:	catalytic step 2 spliceosome [IDA] precatalytic spliceosome [IDA] spliceosomal complex [ISS] small nuclear ribonucleoprotein complex [ISS] U6 snRNP [ISS] U4 snRNP [ISS]
Biological Process:	RNA splicing [ISS] nuclear mRNA splicing, via spliceosome [IC][ISS]
Molecular Function:	U6 snRNA binding [IDA] U4 snRNA binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDDDDIQYI KRQRTLHYGS LEESERKRQN AAASGAAATT TSGTTASSGA GTTTTGTGGQ  60
   61 LEDIDSDEDY EESTKKTSNA KQAGAPPPTA ATLANKIDDD YFDLEMEMER DKVALLEEFE 120
  121 RKKRARQINV STDDTEIKSN LRQLNEPICY FGEGPAERRR RLKELLAGLG ENAINKRQYE 180
  181 DEERKQQQRE QDQATWYHEG PDSLRIARLW LADYSLPRAK DRLVRAREAL EVPSAARAGR 240
  241 MVEMQKKLQS LAPLCSQVGD TRPVSSAAFS EDSSLLLTSS WSGLCKLWSV PDCELKQTLR 300
  301 GHASYVGGVA LRPGVKADEE NVVAMASGGH DGAVKLWGFN NEESIADITG HMPHRVSKVA 360
  361 FHPSGRFLAT ACYDSSWRLW DLEQKTEVLH QEGHAKPVHC LSYHSDGSVL VTGGLDAFGR 420
  421 VWDLRTGRCI MFLEGHLGAV FGVDFSPNGF HIATGSQDNT CKIWDLRRRQ PVYTIPAHTN 480
  481 LISDVKYQQE CGSFLVTCSY DSTTKIWSNK TWQPLKTLQG HDNKVISVDI APNSQYIATT 540
  541 SFDRTFKLWS PDS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: U4-U6-60K-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: