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Protein Overview: FBpp0304463, Dea...

General Information:
Name(s) found: FBpp0304463 [FlyBase]
Deaf1-PA / FBpp0074651 [FlyBase]
Description(s) found:
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  • gi|7293736|gb|AAF49105.1| deformed epidermal autoregulatory factor-1, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|22256750|sp|Q24180.1|DEAF1_DROME RecName: Full=Deformed epidermal autoregulatory factor 1; Short=Protein DEAF-1 [NCBI NR]
  • pir||S69214 deformed epidermal autoregulatory factor-1 - fruit fly (Drosophila melanogaster) [NCBI NR]
  • gi|17737659|ref|NP_524169.1| deformed epidermal autoregulatory factor-1, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|1589475|prf||2211283A DEAF-1 protein [NCBI NR]
  • gi|1209883|gb|AAC47040.1| DEAF-1 [NCBI NR]
  • (Q24180) Deformed epidermal autoregulatory factor 1 (DEAF-1 protein) [Swiss-Prot]
  • Deformed epidermal autoregulatory factor 1 OS=Drosophila melanogaster GN=Deaf1 PE=1 SV=1 [Swiss-Prot]
  • type=protein; loc=3L:join(19811635..19811766,19812312..19813110,19821417..19822045,19822120..19822290); ID=FBpp0304463; name=Deaf1-PD; parent=FBgn0013799,FBtr0332153; dbxref=FlyBase:FBpp0304463,FlyBase_Annotation_IDs:CG8567-PD,REFSEQ:NP_001262069,GB_protein:AGB94762; MD5=55a5351cd579da323dc22dba3837c53c; length=576; release=r5.56; species=Dmel; [FlyBase]
  • The gene Deformed epidermal autoregulatory factor-1 is referred to in FlyBase by the symbol Dmel\Deaf1 (CG8567, FBgn0013799). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:19811280..19822623. It has the cytological map location 76D1. There is experimental evidence that it has the molecular function</span>: transcription factor activity; sequence-specific DNA binding; RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of immune response; embryonic development ending in birth or egg hatching; regulation of gene-specific transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent. 7 alleles are reported. The phenotypes of these alleles are annotated with: wing vein L3; eye; macrochaeta; scutellar bristle; wing; ommatidium; mesothoracic bristle. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG8567-PA translation from_gene[CG8567 Deaf1 FBgn0013799] seq_release:3 mol_weight=61598 cds_boundaries:(3L:19,737,076..19,747,728[+]) aa_length:576 transcript_info:[CG8567-RA seq_release:3] gene_info:[gene symbol:Deaf1 FBgn0013799 gene_boundaries:(3L [hmr_yeast5_DM3-1_pombe.fasta]
  • (AE003515) Deaf1 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG8567-PA [Drosophila melanogaster]gi|17737659|ref|NP_524169.1| CG8567-PA [Drosophila melanogaster]gi|2133648|pir||S69214 deformed epidermal autoregulatory factor-1 - fruit fly (Drosophila melanogaster)gi|1209883|gb|AAC47040.1| DEAF-1gi|22256750|sp|Q [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3L:join(19811635..19811766,19812312..19813110,19821417..19822045,19822120..19822290); ID=FBpp0074651; name=Deaf1-PA; parent=FBgn0013799,FBtr0074882; dbxref=FlyBase_Annotation_IDs:CG8567-PA,FlyBase:FBpp0074651,GB_protein:AAF49105.1,REFSEQ [fly-100309-contam.fasta]
  • DEAF-1 protein [nr-271106-contam.fasta]
  • CG8567-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Deformed epidermal autoregulatory factor-1 CG8567-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • DEAF-1 [nr-271106-contam.fasta]
  • Deformed epidermal autoregulatory factor 1 (Protein DEAF-1) [nr-271106-contam.fasta]
  • type=protein; loc=3L:join(19811635..19811766,19812312..19813110,19821417..19822045,19822120..19822290); ID=FBpp0074651; name=Deaf1-PA; parent=FBgn0013799,FBtr0074882; dbxref=FlyBase_Annotation_IDs:CG8567-PA,FlyBase:FBpp0074651,GB_protein:AAF49105.1,REFSEQ:NP_524169,GB_protein:AAF49105; MD5=55a5351cd579da323dc22dba3837c53c; length=576; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:join(19811635..19811766,19812312..19813110,19821417..19822045,19822120..19822290); ID=FBpp0074651; name=Deaf1-PA; parent=FBgn0013799,FBtr0074882; dbxref=FlyBase_Annotation_IDs:CG8567-PA,FlyBase:FBpp0074651,GB_protein:AAF49105.1,REFSEQ:NP_524169,GB_protein:AAF49105; MD5=55a5351cd579da323dc22dba3837c53c; length=576; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=3L:join(19811635..19811766,19812312..19813110,19821417..19822045,19822120..19822290); ID=FBpp0074651; name=Deaf1-PA; parent=FBgn0013799,FBtr0074882; dbxref=FlyBase_Annotation_IDs:CG8567-PA,FlyBase:FBpp0074651,GB_protein:AAF49105.1,REFSEQ:NP_524169,GB_protein:AAF49105,FlyMine:FBpp0074651,modMine:FBpp0074651; MD5=55a5351cd579da323dc22dba3837c53c; length=576; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3L:join(19811635..19811766,19812312..19813110,19821417..19822045,19822120..19822290); ID=FBpp0304463; name=Deaf1-PD; parent=FBgn0013799,FBtr0332153; dbxref=FlyBase:FBpp0304463,FlyBase_Annotation_IDs:CG8567-PD; MD5=55a5351cd579da323dc22dba3837c53c; length=576; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3L:join(19818535..19818666,19819212..19820010,19828317..19828945,19829020..19829190); ID=FBpp0074651; name=Deaf1-PA; parent=FBgn0013799,FBtr0074882; dbxref=FlyBase_Annotation_IDs:CG8567-PA,FlyBase:FBpp0074651,GB_protein:AAF49105.1,REFSEQ:NP_524169,GB_protein:AAF49105,FlyMine:FBpp0074651,modMine:FBpp0074651; MD5=55a5351cd579da323dc22dba3837c53c; length=576; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:join(19818535..19818666,19819212..19820010,19828317..19828945,19829020..19829190); ID=FBpp0304463; name=Deaf1-PD; parent=FBgn0013799,FBtr0332153; dbxref=FlyBase:FBpp0304463,FlyBase_Annotation_IDs:CG8567-PD,REFSEQ:NP_001262069,GB_protein:AGB94762; MD5=55a5351cd579da323dc22dba3837c53c; length=576; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:join(19818535..19818666,19819212..19820010,19828317..19828945,19829020..19829190); ID=FBpp0074651; name=Deaf1-PA; parent=FBgn0013799,FBtr0074882; dbxref=FlyBase_Annotation_IDs:CG8567-PA,FlyBase:FBpp0074651,GB_protein:AAF49105.1,REFSEQ:NP_524169,GB_protein:AAF49105,FlyMine:FBpp0074651,modMine:FBpp0074651; MD5=55a5351cd579da323dc22dba3837c53c; length=576; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=3L:join(19818535..19818666,19819212..19820010,19828317..19828945,19829020..19829190); ID=FBpp0304463; name=Deaf1-PD; parent=FBgn0013799,FBtr0332153; dbxref=FlyBase:FBpp0304463,FlyBase_Annotation_IDs:CG8567-PD,REFSEQ:NP_001262069,GB_protein:AGB94762; MD5=55a5351cd579da323dc22dba3837c53c; length=576; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q24180, Deformed epidermal autoregulatory factor-1, isoform D OS=Drosophila melanogaster GN=Deaf1 PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0074651 type=protein; loc=3L:join(19818535..19818666,19819212..19820010,19828317..19828945,19829020..19829190); ID=FBpp0074651; name=Deaf1-PA; parent=FBgn0013799,FBtr0074882; dbxref=FlyBase_Annotation_IDs:CG8567-PA,FlyBase:FBpp0074651,GB_protein:AAF49105.1,REFSEQ:NP_524169,GB_protein:AAF49105,FlyMine:FBpp0074651,modMine:FBpp0074651; MD5=55a5351cd579da323dc22dba3837c53c; length=576; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0304463 type=protein; loc=3L:join(19818535..19818666,19819212..19820010,19828317..19828945,19829020..19829190); ID=FBpp0304463; name=Deaf1-PD; parent=FBgn0013799,FBtr0332153; dbxref=FlyBase:FBpp0304463,FlyBase_Annotation_IDs:CG8567-PD,REFSEQ:NP_001262069,GB_protein:AGB94762; MD5=55a5351cd579da323dc22dba3837c53c; length=576; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3L:join(19818535..19818666,19819212..19820010,19828317..19828945,19829020..19829190); ID=FBpp0074651; name=Deaf1-PA; parent=FBgn0013799,FBtr0074882; dbxref=FlyBase_Annotation_IDs:CG8567-PA,FlyBase:FBpp0074651,GB_protein:AAF49105.1,REFSEQ:NP_524169,GB_protein:AAF49105,UniProt/Swiss-Prot:Q24180,FlyMine:FBpp0074651,modMine:FBpp0074651; MD5=55a5351cd579da323dc22dba3837c53c; length=576; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=3L:join(19818535..19818666,19819212..19820010,19828317..19828945,19829020..19829190); ID=FBpp0304463; name=Deaf1-PD; parent=FBgn0013799,FBtr0332153; dbxref=FlyBase:FBpp0304463,FlyBase_Annotation_IDs:CG8567-PD,REFSEQ:NP_001262069,GB_protein:AGB94762,UniProt/Swiss-Prot:Q24180; MD5=55a5351cd579da323dc22dba3837c53c; length=576; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 576 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    polytene chromosome [IDA]
    Biological Process: positive regulation of transcription, DNA-dependent [IDA]
    embryonic development ending in birth or egg hatching [IMP]
    regulation of gene-specific transcription from RNA polymerase II promoter [IDA]
    regulation of immune response [IDA]
    Molecular Function: zinc ion binding [IEA]
    transcription factor activity [IDA]
    RNA polymerase II transcription factor activity [IDA]
    sequence-specific DNA binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQVDSSTEL HLNRKDLAAL AEDVVKEEVI LESSSHHHHH HHHQLDTKVR MVTSSSNDNS  60
   61 GSGGASGGTS GAGGGNGGGG VVSVPVSLPI GSMITGTTFN VITPDQLPPH FKPMLCVDNN 120
  121 GYLSGSTVSM GNDLKTIVIQ QQQTQPGGGG GGANNAGTNT TATNTIGLNH DGSGSNNSHD 180
  181 SLATLEHAAG GASGVGGGGG GTGGGSSGWS ENPSTQHNEV FQIRCKTTCA ELYRSKLGSG 240
  241 GRGRCVKYKD KWHTPSEFEH VCGRGSSKDW KRSIKYGGKS LQSLIDEGTL TPHATNCSCT 300
  301 VCCDDEAGES ASGPVRLFTP YKRRKRNQTD LDMESGPKRK RNTHHSNNNN SNTNNNNTSG 360
  361 SGANNCVDVT AAVAAATASV VDENNMFLSE ENITSKDEPW AALNDSLDTS TELVDQSQMG 420
  421 NTYERETFVV NINDGSSIAV LDTSQSMKNI EHVYCTMVKA TNDFKRMLND MKQSFERRIE 480
  481 VLQKERDAAV SAMRVQVHAD IDDPNISGSL HGNEIISAKK CANCNREALA ECSLCRKTPY 540
  541 CSEFCQRKDW NAHQVECTRN PQTTTQQVML LIDDQS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle