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Protein Overview: CG8774-PB

General Information:
Name(s) found: CG8774-PB / FBpp0082208 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG8774 (CG8774, FBgn0038136). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:9124569..9128056. It has the cytological map location 87E4-87E5. Based on sequence similarity, it is predicted to have molecular function</span>: aminopeptidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: proteolysis. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 885 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: proteolysis [IEA]
    Molecular Function: zinc ion binding [IEA]
    aminopeptidase activity [ISS]
    metallopeptidase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKREDTTDYR LPTNLVPTHY ELYWHPDLET GNFTGQQRIS IKVVEATNQI ILHSYLLDIT  60
   61 SVYVLNREVE KFELEEERQF LIITLTEELA VDASITLGII FGGQMKDKLV GLYSSTYLNE 120
  121 AGATRTISTT KFEPTYARQA FPCFDEPAMK ATFAITVVHP SGSYHAVSNM QQTESNYLGD 180
  181 YTEAIFETSV SMSTYLVCII VSDFASQSTT VKANGIGEDF SMQAYATSHQ INKVEFALEF 240
  241 GQAVTEYYIQ YYKVPYPLTK LDMAAIPDFA SGAMEHWGLV TYRETALLYD PSYSSTANKQ 300
  301 SIAGTLAHEI AHQWFGNLVT MKWWNDLWLN EGFARYMQYK GVNAVHPDWG MLEQFQIVAL 360
  361 QPVLLYDAKL SSHPIVQKVE SPDEITAIFD TISYEKGGSV IRMLETLVGA EKFEEAVTNY 420
  421 LVKHQFNNTV TDDFLTEVEA VVTDLDIKKL MLTWTEQMGY PVLNVSKVAD GSFKVTQQRF 480
  481 LSNPASYEEA PSDSAYGYKW SVPITWFADD GSENSFIYDY DVDSVGIAVP SEVQWIKLNV 540
  541 NQTGYYRVNY EESLWALLIQ QLTTSPARFE IADRGHLLND AFALADANQL SYKIPLDMTA 600
  601 YLAQERDFVP WYVASNKLRS LHRSLMFSEG YVSYLTYARS LIAGVYEEVG WTVDADNHLK 660
  661 NRLRVSILTA ACALGVPDCL QQASERFSTF LENPTTRPSP DLREIVYYYG MQQSTSQSSW 720
  721 DQLFQLFVAE TDASEKLKLM YGLSGVRNSQ YLFDFLAQAS SDESIVRSQD YFTCVQYIAA 780
  781 NPVGEPVVWE FYREQWPQLT TRFGLNNRNF GRLIAQITAN FASSVKLEEV QHFFSKYPES 840
  841 GAGANSRLEA VETIKYNIEW LSRNEADITD WLSGTASPLT KKNQL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..885] PSI-BLAST 130.0 Crystal structures of the tricorn interacting facor F3 from Thermoplasma acidophilum, a zinc aminopeptidase in three different conformations


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle