Protein Overview: CG8774-PB

General Information:
Name(s) found:	CG8774-PB / FBpp0082208 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|24646512\|ref\|NP_731785.1\| CG8774, isoform B [Drosophila melanogaster] [NCBI NR] gi\|23171149\|gb\|AAF54927.2\| CG8774, isoform B [Drosophila melanogaster] [NCBI NR] This gene is referred to in FlyBase by the symbol Dmel\CG8774 (CG8774, FBgn0038136). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:9124569..9128056. It has the cytological map location 87E4-87E5. Based on sequence similarity, it is predicted to have molecular function</span>: aminopeptidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: proteolysis. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] >CG8774-PB translation from_gene[CG8774 CG8774 FBgn0038136] seq_release:3 mol_weight=100475 cds_boundaries:(3R:9,124,926..9,127,969[+]) aa_length:885 transcript_info:[CG8774-RB seq_release:3] gene_info:[gene symbol:CG8774 FBgn0038136 gene_boundaries:(3 [hmr_yeast5_DM3-1_pombe.fasta] (Q9VFW8) CG8774 protein [DrosMelano7227.FASTAC.txt] CG8774-PB, isoform B [Drosophila melanogaster]gi\|24646512\|ref\|NP_731785.1\| CG8774-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3R:join(9124907..9124924,9124983..9125338,9125473..9125617,9125672..9126205,9126268..9127196,9127278..9127953); ID=FBpp0082208; name=CG8774-PB; parent=FBgn0038136,FBtr0082740; dbxref=FlyBase:FBpp0082208,FlyBase_Annotation_IDs:CG8774-PB,G [fly-100309-contam.fasta] CG8774-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3R:join(9124907..9124924,9124983..9125338,9125473..9125617,9125672..9126205,9126268..9127196,9127278..9127953); ID=FBpp0082208; name=CG8774-PB; parent=FBgn0038136,FBtr0082740; dbxref=FlyBase:FBpp0082208,FlyBase_Annotation_IDs:CG8774-PB,GB_protein:AAF54927.2,REFSEQ:NP_731785,GB_protein:AAF54927; MD5=8e53328fd179e7523402a52edb48d673; length=885; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3R:join(9124907..9124924,9124983..9125338,9125473..9125617,9125672..9126205,9126268..9127196,9127278..9127953); ID=FBpp0082208; name=CG8774-PB; parent=FBgn0038136,FBtr0082740; dbxref=FlyBase:FBpp0082208,FlyBase_Annotation_IDs:CG8774-PB,GB_protein:AAF54927.2,REFSEQ:NP_731785,GB_protein:AAF54927; MD5=8e53328fd179e7523402a52edb48d673; length=885; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] CG8774, isoform B OS=Drosophila melanogaster GN=CG8774 PE=1 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3R:join(9124907..9124924,9124983..9125338,9125473..9125617,9125672..9126205,9126268..9127196,9127278..9127953); ID=FBpp0082208; name=CG8774-PB; parent=FBgn0038136,FBtr0082740; dbxref=FlyBase:FBpp0082208,FlyBase_Annotation_IDs:CG8774-PB,GB_protein:AAF54927.2,REFSEQ:NP_731785,GB_protein:AAF54927,FlyMine:FBpp0082208,modMine:FBpp0082208; MD5=8e53328fd179e7523402a52edb48d673; length=885; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] CG8774, isoform B OS=Drosophila melanogaster GN=CG8774 PE=4 SV=2 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta] type=protein; loc=3R:join(13299185..13299202,13299261..13299616,13299751..13299895,13299950..13300483,13300546..13301474,13301556..13302231); ID=FBpp0082208; name=CG8774-PB; parent=FBgn0038136,FBtr0082740; dbxref=FlyBase:FBpp0082208,FlyBase_Annotation_IDs:CG8774-PB,GB_protein:AAF54927.2,REFSEQ:NP_731785,GB_protein:AAF54927,FlyMine:FBpp0082208,modMine:FBpp0082208; MD5=8e53328fd179e7523402a52edb48d673; length=885; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3R:join(13299185..13299202,13299261..13299616,13299751..13299895,13299950..13300483,13300546..13301474,13301556..13302231); ID=FBpp0082208; name=CG8774-PB; parent=FBgn0038136,FBtr0082740; dbxref=FlyBase:FBpp0082208,FlyBase_Annotation_IDs:CG8774-PB,GB_protein:AAF54927.2,REFSEQ:NP_731785,GB_protein:AAF54927,FlyMine:FBpp0082208,modMine:FBpp0082208; MD5=8e53328fd179e7523402a52edb48d673; length=885; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Isoform of Q9VFW9, CG8774, isoform B OS=Drosophila melanogaster GN=CG8774 PE=1 SV=2 [DROME.fasta.20160308] FBpp0082208 type=protein; loc=3R:join(13299185..13299202,13299261..13299616,13299751..13299895,13299950..13300483,13300546..13301474,13301556..13302231); ID=FBpp0082208; name=CG8774-PB; parent=FBgn0038136,FBtr0082740; dbxref=FlyBase:FBpp0082208,FlyBase_Annotation_IDs:CG8774-PB,GB_protein:AAF54927.2,REFSEQ:NP_731785,GB_protein:AAF54927,FlyMine:FBpp0082208,modMine:FBpp0082208; MD5=8e53328fd179e7523402a52edb48d673; length=885; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3R:join(13299185..13299202,13299261..13299616,13299751..13299895,13299950..13300483,13300546..13301474,13301556..13302231); ID=FBpp0082208; name=CG8774-PB; parent=FBgn0038136,FBtr0082740; dbxref=FlyBase:FBpp0082208,FlyBase_Annotation_IDs:CG8774-PB,GB_protein:AAF54927.2,REFSEQ:NP_731785,GB_protein:AAF54927,UniProt/TrEMBL:Q9VFW8,FlyMine:FBpp0082208,modMine:FBpp0082208; MD5=8e53328fd179e7523402a52edb48d673; length=885; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	885 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	proteolysis [IEA]
Molecular Function:	zinc ion binding [IEA] aminopeptidase activity [ISS] metallopeptidase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKREDTTDYR LPTNLVPTHY ELYWHPDLET GNFTGQQRIS IKVVEATNQI ILHSYLLDIT  60
   61 SVYVLNREVE KFELEEERQF LIITLTEELA VDASITLGII FGGQMKDKLV GLYSSTYLNE 120
  121 AGATRTISTT KFEPTYARQA FPCFDEPAMK ATFAITVVHP SGSYHAVSNM QQTESNYLGD 180
  181 YTEAIFETSV SMSTYLVCII VSDFASQSTT VKANGIGEDF SMQAYATSHQ INKVEFALEF 240
  241 GQAVTEYYIQ YYKVPYPLTK LDMAAIPDFA SGAMEHWGLV TYRETALLYD PSYSSTANKQ 300
  301 SIAGTLAHEI AHQWFGNLVT MKWWNDLWLN EGFARYMQYK GVNAVHPDWG MLEQFQIVAL 360
  361 QPVLLYDAKL SSHPIVQKVE SPDEITAIFD TISYEKGGSV IRMLETLVGA EKFEEAVTNY 420
  421 LVKHQFNNTV TDDFLTEVEA VVTDLDIKKL MLTWTEQMGY PVLNVSKVAD GSFKVTQQRF 480
  481 LSNPASYEEA PSDSAYGYKW SVPITWFADD GSENSFIYDY DVDSVGIAVP SEVQWIKLNV 540
  541 NQTGYYRVNY EESLWALLIQ QLTTSPARFE IADRGHLLND AFALADANQL SYKIPLDMTA 600
  601 YLAQERDFVP WYVASNKLRS LHRSLMFSEG YVSYLTYARS LIAGVYEEVG WTVDADNHLK 660
  661 NRLRVSILTA ACALGVPDCL QQASERFSTF LENPTTRPSP DLREIVYYYG MQQSTSQSSW 720
  721 DQLFQLFVAE TDASEKLKLM YGLSGVRNSQ YLFDFLAQAS SDESIVRSQD YFTCVQYIAA 780
  781 NPVGEPVVWE FYREQWPQLT TRFGLNNRNF GRLIAQITAN FASSVKLEEV QHFFSKYPES 840
  841 GAGANSRLEA VETIKYNIEW LSRNEADITD WLSGTASPLT KKNQL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..885]	PSI-BLAST	130.0	Crystal structures of the tricorn interacting facor F3 from Thermoplasma acidophilum, a zinc aminopeptidase in three different conformations

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: CG8774-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: