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Protein Overview: CG8774-PA

General Information:
Name(s) found: CG8774-PA / FBpp0082209 [FlyBase]
Description(s) found:
Found 18 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG8774 (CG8774, FBgn0038136). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:9124569..9128056. It has the cytological map location 87E4-87E5. Based on sequence similarity, it is predicted to have molecular function</span>: aminopeptidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: proteolysis. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 942 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: proteolysis [IEA]
    Molecular Function: zinc ion binding [IEA]
    aminopeptidase activity [ISS]
    metallopeptidase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFLSGYWLQV VLSWAVVAFA TATVVVAVQK AQLERDLRDV QDKIDVFEEW SGESRTRMKR  60
   61 EDTTDYRLPT NLVPTHYELY WHPDLETGNF TGQQRISIKV VEATNQIILH SYLLDITSVY 120
  121 VLNREVEKFE LEEERQFLII TLTEELAVDA SITLGIIFGG QMKDKLVGLY SSTYLNEAGA 180
  181 TRTISTTKFE PTYARQAFPC FDEPAMKATF AITVVHPSGS YHAVSNMQQT ESNYLGDYTE 240
  241 AIFETSVSMS TYLVCIIVSD FASQSTTVKA NGIGEDFSMQ AYATSHQINK VEFALEFGQA 300
  301 VTEYYIQYYK VPYPLTKLDM AAIPDFASGA MEHWGLVTYR ETALLYDPSY SSTANKQSIA 360
  361 GTLAHEIAHQ WFGNLVTMKW WNDLWLNEGF ARYMQYKGVN AVHPDWGMLE QFQIVALQPV 420
  421 LLYDAKLSSH PIVQKVESPD EITAIFDTIS YEKGGSVIRM LETLVGAEKF EEAVTNYLVK 480
  481 HQFNNTVTDD FLTEVEAVVT DLDIKKLMLT WTEQMGYPVL NVSKVADGSF KVTQQRFLSN 540
  541 PASYEEAPSD SAYGYKWSVP ITWFADDGSE NSFIYDYDVD SVGIAVPSEV QWIKLNVNQT 600
  601 GYYRVNYEES LWALLIQQLT TSPARFEIAD RGHLLNDAFA LADANQLSYK IPLDMTAYLA 660
  661 QERDFVPWYV ASNKLRSLHR SLMFSEGYVS YLTYARSLIA GVYEEVGWTV DADNHLKNRL 720
  721 RVSILTAACA LGVPDCLQQA SERFSTFLEN PTTRPSPDLR EIVYYYGMQQ STSQSSWDQL 780
  781 FQLFVAETDA SEKLKLMYGL SGVRNSQYLF DFLAQASSDE SIVRSQDYFT CVQYIAANPV 840
  841 GEPVVWEFYR EQWPQLTTRF GLNNRNFGRL IAQITANFAS SVKLEEVQHF FSKYPESGAG 900
  901 ANSRLEAVET IKYNIEWLSR NEADITDWLS GTASPLTKKN QL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..942] PSI-BLAST 126.0 Crystal structures of the tricorn interacting facor F3 from Thermoplasma acidophilum, a zinc aminopeptidase in three different conformations


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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