Protein Overview: ash2-PD

General Information:
Name(s) found:	ash2-PD / FBpp0113037 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|221459037\|ref\|NP_733023.3\| absent, small, or homeotic discs 2, isoform D [Drosophila melanogaster] [NCBI NR] gi\|220903197\|gb\|AAF56320.3\| absent, small, or homeotic discs 2, isoform D [Drosophila melanogaster] [NCBI NR] The gene absent, small, or homeotic discs 2 is referred to in FlyBase by the symbol Dmel\ash2 (CG6677, FBgn0000139). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:20475769..20479099. It has the cytological map location 96A13. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: zinc ion binding; protein binding. There is experimental evidence that it is involved in the biological process</span>: imaginal disc-derived wing vein specification; chromatin-mediated maintenance of transcription; imaginal disc-derived wing morphogenesis. 28 alleles are reported. The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: adult segment; organ system; thoracic segment; adult mesothoracic segment; appendage segment; adult metathoracic segment; imaginal precursor; adult; dorsal thoracic disc; multi-cell-component structure; antennal segment; mouthpart. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase] >CG6677-PA translation from_gene[CG6677 ash2 FBgn0000139] seq_release:3 mol_weight=64862 cds_boundaries:(3R:20,466,503..20,469,578[+]) aa_length:572 transcript_info:[CG6677-RA seq_release:3] gene_info:[gene symbol:ash2 FBgn0000139 gene_boundaries:(3R:2 [hmr_yeast5_DM3-1_pombe.fasta] (Q9VC55) ASH2 protein [DrosMelano7227.FASTAC.txt] (AE003748) ash2 gene product [Drosophila melanogaster] [yeastflysequest.fasta] type=protein; loc=3R:join(20475846..20475899,20475957..20476066,20476127..20476311,20476372..20476716,20477583..20477963,20478032..20478312,20478504..20478761,20478820..20478924); ID=FBpp0113037; name=ash2-PD; parent=FBgn0000139,FBtr0114545; dbxref=FlyBas [fly-100309-contam.fasta] type=protein; loc=3R:join(20475846..20475899,20475957..20476066,20476127..20476311,20476372..20476716,20477583..20477963,20478032..20478312,20478504..20478761,20478820..20478924); ID=FBpp0113037; name=ash2-PD; parent=FBgn0000139,FBtr0114545; dbxref=FlyBase:FBpp0113037,FlyBase_Annotation_IDs:CG6677-PD,REFSEQ:NP_733023,GB_protein:AAF56320; MD5=df6f56fb6b96f4585a9dcde819b49791; length=572; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3R:join(20475846..20475899,20475957..20476066,20476127..20476311,20476372..20476716,20477583..20477963,20478032..20478312,20478504..20478761,20478820..20478924); ID=FBpp0113037; name=ash2-PD; parent=FBgn0000139,FBtr0114545; dbxref=FlyBase:FBpp0113037,FlyBase_Annotation_IDs:CG6677-PD,REFSEQ:NP_733023,GB_protein:AAF56320; MD5=df6f56fb6b96f4585a9dcde819b49791; length=572; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Absent, small, or homeotic discs 2, isoform D OS=Drosophila melanogaster GN=ash2 PE=2 SV=3 [UniProt_drosophila_07-01-2011_reversed.fasta]
Organism:	Drosophila melanogaster
Length:	572 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA][ISS]
Biological Process:	imaginal disc-derived wing morphogenesis [IMP] imaginal disc-derived wing vein specification [IGI][IMP] chromatin-mediated maintenance of transcription [IMP]
Molecular Function:	zinc ion binding [IEA] protein binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCLPANGHSG QPPNFLRADS QMDTSSPTES SSEVNFTAEE DKSQETRSAA GVCYCGKERN  60
   61 LNIVELLCAT CSRWVHETCV SYQLGKGKLL PFITNYVFVC KNCSASGLES FRKSQATISQ 120
  121 MCHCAIANMQ QAASRDGRRQ IQFSKDKEII PYIEQYWEAM TTMPRRLTQS WYSTVQRSLV 180
  181 KDVQTLFTYE EHAEHGAMYG LFHQDLRIIK PNYESMSKSG ALRLTDDGYT QASLSKNNRQ 240
  241 KRKFPGTDSG PTGKKGRPSS DITANVKLPP HGYPLEHPFN KDGYRYILAE PDPHAPFRQE 300
  301 FDESSDWAGK PIPGWLYRIL VPHSVLLALH DRAPQLKISE DRLAVTGERG YCMVRATHSV 360
  361 NRGCWYFEVT IEEMPDGAAT RLGWGREYGN LQAPLGYDKF GYSWRSRKGT KFTESHGKHY 420
  421 SDAYVEGDTL GFLIELPEEA SLDYLPNTFK DRPLVKFKSH LYYEDKDKIT ETLKNLHILQ 480
  481 GSRIEFFKNG QSQGVAFEDI YAGSYFPAIS IHKSATVSVN FGPAFKYPEV LVEHKAKGMH 540
  541 DRVEELITEQ CLADTLYLTE HDGRLRLDNM GL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: ash2-PD

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: