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Protein Overview: CDase-PA, CDase-...

General Information:
Name(s) found: FBpp0303775 [FlyBase]
CDase-PE / FBpp0085011 [FlyBase]
CDase-PD / FBpp0085010 [FlyBase]
CDase-PC / FBpp0085009 [FlyBase]
CDase-PA / FBpp0085008 [FlyBase]
CDase-PB / FBpp0085007 [FlyBase]
Description(s) found:
Found 81 descriptions.
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  • type=protein; loc=3R:join(26288563..26288691,26288754..26289077,26289137..26290003,26290429..26291039,26291100..26291283); ID=FBpp0303775; name=CDase-PF; parent=FBgn0039774,FBtr0331357; dbxref=FlyBase:FBpp0303775,FlyBase_Annotation_IDs:CG1471-PF,REFSEQ:NP_001263109,GB_protein:AGB96488; MD5=ab720520b68928e0203780b0f4997ff0; length=704; release=r5.56; species=Dmel; [FlyBase]
  • The gene Ceramidase is referred to in FlyBase by the symbol Dmel\CDase (CG1471, FBgn0039774). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:26285511..26291458. It has the cytological map location 99F5-99F6. There is experimental evidence that it has the molecular function</span>: ceramidase activity. There is experimental evidence that it is involved in the biological process</span>: synaptic transmission; sphingolipid metabolic process; ceramide catabolic process; synaptic vesicle fusion to presynaptic membrane; hatching behavior; synaptic vesicle exocytosis. 8 alleles are reported. The phenotype of these alleles is annotated with: synaptic vesicle. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
  • The gene Ceramidase is referred to in FlyBase by the symbol Dmel\CDase (CG1471, FBgn0039774). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:26285511..26291458. It has the cytological map location 99F5-99F6. There is experimental evidence that it has the molecular function</span>: ceramidase activity. There is experimental evidence that it is involved in the biological process</span>: synaptic transmission; sphingolipid metabolic process; ceramide catabolic process; synaptic vesicle fusion to presynaptic membrane; hatching behavior; synaptic vesicle exocytosis. 8 alleles are reported. The phenotype of these alleles is annotated with: synaptic vesicle. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
  • The gene Ceramidase is referred to in FlyBase by the symbol Dmel\CDase (CG1471, FBgn0039774). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:26285511..26291458. It has the cytological map location 99F5-99F6. There is experimental evidence that it has the molecular function</span>: ceramidase activity. There is experimental evidence that it is involved in the biological process</span>: synaptic transmission; sphingolipid metabolic process; ceramide catabolic process; synaptic vesicle fusion to presynaptic membrane; hatching behavior; synaptic vesicle exocytosis. 8 alleles are reported. The phenotype of these alleles is annotated with: synaptic vesicle. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
  • The gene Ceramidase is referred to in FlyBase by the symbol Dmel\CDase (CG1471, FBgn0039774). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:26285511..26291458. It has the cytological map location 99F5-99F6. There is experimental evidence that it has the molecular function</span>: ceramidase activity. There is experimental evidence that it is involved in the biological process</span>: synaptic transmission; sphingolipid metabolic process; ceramide catabolic process; synaptic vesicle fusion to presynaptic membrane; hatching behavior; synaptic vesicle exocytosis. 8 alleles are reported. The phenotype of these alleles is annotated with: synaptic vesicle. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
  • The gene Ceramidase is referred to in FlyBase by the symbol Dmel\CDase (CG1471, FBgn0039774). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:26285511..26291458. It has the cytological map location 99F5-99F6. There is experimental evidence that it has the molecular function</span>: ceramidase activity. There is experimental evidence that it is involved in the biological process</span>: synaptic transmission; sphingolipid metabolic process; ceramide catabolic process; synaptic vesicle fusion to presynaptic membrane; hatching behavior; synaptic vesicle exocytosis. 8 alleles are reported. The phenotype of these alleles is annotated with: synaptic vesicle. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 704 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDA]
    extracellular region [IDA]
    Biological Process: hatching behavior [IMP]
    photoreceptor cell maintenance [IMP]
    synaptic vesicle fusion to presynaptic membrane [IMP]
    synaptic transmission [IMP]
    synaptic vesicle exocytosis [IMP]
    ceramide catabolic process [IDA]
    sphingolipid metabolic process [IDA]
    Molecular Function: ceramidase activity [IDA][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANSKMAFLA FLAVSFLCGL VSATYKVGVG RADITGPPVE INFMGYANIK QVGRGIHTRV  60
   61 FARAFVVEDE KGNRVAFVSA DAGMMGYGLK REVIKRLQAR YGNIYHNDNV AISGTHTHGA 120
  121 PGGFLMHLLY DISILGFVPQ TFEVMAQGLY LCIKRATDNL VDGRILLSKT TVLNVNINRS 180
  181 PSSYLRNPAE ERAQYEHDTD KTLTQLRFVD LENNLLGAFN WYAVHATSMN NTNRLVTSDN 240
  241 VGYAALLLEK EYNPNKMPGK GKFVGAFCSS NLGDVSPNIM GPKCSISGNE CDLLTSRCPT 300
  301 GEGDCFASGP GKDMFESTQI LGQRLADAAL GLLNEQSQES TAREVTGDVR FIHQFVDMPN 360
  361 YNGSTYNPLS RKVDKIRGCQ PAMGYSFAAG TTDGPGAFSF EQGTTTDNPM WNFVRDFIAA 420
  421 PTQEDIKCHE PKPILLATGR ATFPYEWQPK IVSDQLLKIG DVIIAAVPCE FTTMAGRRLR 480
  481 NQIRAAASAV GGIDTEVIIA GLTNIYTSYT VTPEEYQAQR YEAASTIFGP HTHSIYMDVF 540
  541 ERLTKAMMRN ETVDAGPSPP YMNDVMLSLN TGVLFDGHPI NTDFGYVKSQ PNKEYGINET 600
  601 VKVTYISGNP RNNLFTEKTY FTIERKINED RWKVAYTDAS WETKMVWHRT NTILGFSEMD 660
  661 IYWDISPQTL PGEYRIRHSG EYKYILGGKY PYEGLTHSFT VKED

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..195] MSA 1.061951 View MSA. No confident structure predictions are available.
    2 View Details [196..259] deduced N/A No confident structure predictions are available.
    3 View Details [260..475] MSA 1.044976 View MSA. No confident structure predictions are available.
    4 View Details [476..550] deduced N/A No confident structure predictions are available.
    5 View Details [551..704] MSA 5.042955 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle