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Protein Overview: CG1885-PA, FBpp0...

General Information:
Name(s) found: FBpp0305783 [FlyBase]
CG1885-PA / FBpp0071211 [FlyBase]
Description(s) found:
Found 27 descriptions.
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  • type=protein; loc=X:complement(8793260..8794093); ID=FBpp0305783; name=CG1885-PB; parent=FBgn0030066,FBtr0333606; dbxref=REFSEQ:NP_001259362,GB_protein:AGB95205,FlyBase:FBpp0305783,FlyBase_Annotation_IDs:CG1885-PB; MD5=807f56b1aa9ac1bb28f08cceebe4c5f5; length=277; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG1885 (CG1885, FBgn0030066). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:8793065..8794211. It has the cytological map location 8B6. Based on sequence similarity, it is predicted to have molecular function</span>: uroporphyrinogen-III synthase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: tetrapyrrole biosynthetic process. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 277 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: tetrapyrrole biosynthetic process [IEA]
    Molecular Function: uroporphyrinogen-III synthase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSRQRTVII FKSESESSDV YAETLEKHDF NPVFVPTLSF GFKNLDELRA KLQNPDKYAG  60
   61 IIFTSPRCVE AVAESLNLGE LPGGWKMLHN YAVGEVTHNL ALSTLDQLFT HGKQTGNARA 120
  121 LGDYIVDTFD GSRALPLLLP CGNLATDTLL SKLAENGFSV DACEVYETRC HPELGANVER 180
  181 ALEIYGESIE FLAFFSPSGV NCAQQYFTSR QLSMDKWKLV AIGPSTRRAL ESLGQKVYCT 240
  241 AERPTVEHLV KVLLNPQDSR ERLLKERERM AAIENNN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..277] PSI-BLAST 51.69897 Uroporphyrinogen III synthase (U3S, HemD)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • uroporphyrinogen-III synthase activity
    		•  3.75954315324218 bayes_pls_golite062009
  • binding
    		•  1.39689732651231 bayes_pls_golite062009
  • catalytic activity
    		•  1.13824203225664 bayes_pls_golite062009
  • hydro-lyase activity
    		•  0.290711782955013 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle