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Protein Overview: l(1)G0232-PB

General Information:
Name(s) found: l(1)G0232-PB / FBpp0099555 [FlyBase]
Description(s) found:
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  • gi|24640860|ref|NP_727357.1| lethal (1) G0232, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|22833039|gb|AAF46513.2| lethal (1) G0232, isoform B [Drosophila melanogaster] [NCBI NR]
  • The gene lethal (1) G0232 is referred to in FlyBase by the symbol Dmel\l(1)G0232 (CG32697, FBgn0028341). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:9522732..9552947. It has the cytological map location 8F2-8F6. Based on sequence similarity, it is predicted to have molecular function</span>: non-membrane spanning protein tyrosine phosphatase activity. There is experimental evidence that it is involved in the biological process</span>: phagocytosis, engulfment. 25 alleles are reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
  • >CG32697-PB translation from_gene[CG32697 CG32697 FBgn0052697] seq_release:3 mol_weight=86533 cds_boundaries:(X:9,368,093..9,384,733[-]) aa_length:802 transcript_info:[CG32697-RB seq_release:3] gene_info:[gene symbol:CG32697 synonyms:[CG3102 CG3101] FB [hmr_yeast5_DM3-1_pombe.fasta]
  • (AAF46513) CG32697-PB [DrosMelano7227.FASTAC.txt]
  • CG32697-PB, isoform B [Drosophila melanogaster]gi|24640860|ref|NP_727357.1| CG32697-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=X:complement(9523139..9523365,9523429..9523636,9523701..9523930,9523996..9524156,9524227..9525128,9537690..9537920,9537990..9538400,9539744..9539782); ID=FBpp0099555; name=l(1)G0232-PB; parent=FBgn0028341,FBtr0071406; dbxref=FlyBase_Anno [fly-100309-contam.fasta]
  • CG32697-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • lethal (1) G0232 CG32697-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=X:complement(9523139..9523365,9523429..9523636,9523701..9523930,9523996..9524156,9524227..9525128,9537690..9537920,9537990..9538400,9539744..9539782); ID=FBpp0099555; name=l(1)G0232-PB; parent=FBgn0028341,FBtr0071406; dbxref=FlyBase_Annotation_IDs:CG32697-PB,FlyBase:FBpp0099555,GB_protein:AAF46513.2,REFSEQ:NP_727357,GB_protein:AAF46513; MD5=71d32ac95047cc106b4f6d125c17702c; length=802; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=X:complement(9523139..9523365,9523429..9523636,9523701..9523930,9523996..9524156,9524227..9525128,9537690..9537920,9537990..9538400,9539744..9539782); ID=FBpp0099555; name=l(1)G0232-PB; parent=FBgn0028341,FBtr0071406; dbxref=FlyBase_Annotation_IDs:CG32697-PB,FlyBase:FBpp0099555,GB_protein:AAF46513.2,REFSEQ:NP_727357,GB_protein:AAF46513; MD5=71d32ac95047cc106b4f6d125c17702c; length=802; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • LP18470p OS=Drosophila melanogaster GN=l(1)G0232 PE=2 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=X:complement(9523139..9523365,9523429..9523636,9523701..9523930,9523996..9524156,9524227..9525128,9537690..9537920,9537990..9538400,9539744..9539782); ID=FBpp0099555; name=l(1)G0232-PB; parent=FBgn0028341,FBtr0071406; dbxref=FlyBase_Annotation_IDs:CG32697-PB,FlyBase:FBpp0099555,GB_protein:AAF46513.2,REFSEQ:NP_727357,GB_protein:AAF46513,FlyMine:FBpp0099555,modMine:FBpp0099555; MD5=71d32ac95047cc106b4f6d125c17702c; length=802; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=X:complement(join(9645711..9645749,9643957..9644367,9643657..9643887,9630194..9631095,9629963..9630123,9629668..9629897,9629396..9629603,9629106..9629332)); ID=FBpp0099555; name=l(1)G0232-PB; parent=FBgn0028341,FBtr0071406; dbxref=FlyBase_Annotation_IDs:CG32697-PB,FlyBase:FBpp0099555,GB_protein:AAF46513.2,REFSEQ:NP_727357,GB_protein:AAF46513,FlyMine:FBpp0099555,modMine:FBpp0099555; MD5=71d32ac95047cc106b4f6d125c17702c; length=802; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=X:complement(join(9645711..9645749,9643957..9644367,9643657..9643887,9630194..9631095,9629963..9630123,9629668..9629897,9629396..9629603,9629106..9629332)); ID=FBpp0099555; name=Ptpmeg2-PB; parent=FBgn0028341,FBtr0071406; dbxref=FlyBase_Annotation_IDs:CG32697-PB,FlyBase:FBpp0099555,GB_protein:AAF46513.2,REFSEQ:NP_727357,GB_protein:AAF46513,FlyMine:FBpp0099555,modMine:FBpp0099555; MD5=71d32ac95047cc106b4f6d125c17702c; length=802; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q9W323, LP18470p OS=Drosophila melanogaster GN=Ptpmeg2 PE=1 SV=2 [DROME.fasta.20160308]
  • FBpp0099555 type=protein; loc=X:complement(join(9645711..9645749,9643957..9644367,9643657..9643887,9630194..9631095,9629963..9630123,9629668..9629897,9629396..9629603,9629106..9629332)); ID=FBpp0099555; name=Ptpmeg2-PB; parent=FBgn0028341,FBtr0071406; dbxref=FlyBase_Annotation_IDs:CG32697-PB,FlyBase:FBpp0099555,GB_protein:AAF46513.2,REFSEQ:NP_727357,GB_protein:AAF46513,FlyMine:FBpp0099555,modMine:FBpp0099555; MD5=71d32ac95047cc106b4f6d125c17702c; length=802; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=X:complement(join(9645711..9645749,9643957..9644367,9643657..9643887,9630194..9631095,9629963..9630123,9629668..9629897,9629396..9629603,9629106..9629332)); ID=FBpp0099555; name=Ptpmeg2-PB; parent=FBgn0028341,FBtr0071406; dbxref=FlyBase_Annotation_IDs:CG32697-PB,FlyBase:FBpp0099555,GB_protein:AAF46513.2,REFSEQ:NP_727357,GB_protein:AAF46513,UniProt/TrEMBL:Q9W324,FlyMine:FBpp0099555,modMine:FBpp0099555; MD5=71d32ac95047cc106b4f6d125c17702c; length=802; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 802 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: phagocytosis, engulfment [IMP]
    protein amino acid dephosphorylation [IEA][NAS]
    Molecular Function: non-membrane spanning protein tyrosine phosphatase activity [ISS]
    protein tyrosine phosphatase activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVHLYQRRRN REQAVKQFID LCNNLGANCS TTTATSPSTS SSSASSTQNL IAVVPPQLQQ  60
   61 LQVQLPAPGG GGGAGAGGGG GGGGGAAPVR RHISHTTAVK FLYARKFDIP RAVSLYEQHE 120
  121 QIRLKEYLYN IDPDVEPLRS ELQTGKFTIL PARTSSGAAI ALFTANRHSP LSVSHTTTLQ 180
  181 GIVYQLDSAL QDSETQRAGL VFIYDMSGSK YSNFDYDLSQ KILTLLKGGY PARLKKVLIV 240
  241 TAPLWFKAPF KILRLFVREK LRERVFTVSV PQLALHVPRK ALPIHLGGTL EVDHATWLLS 300
  301 CRQSMTNRED ELLANIVGVG GGSGSGSAAG SAAIVSTNGT ETEAATTAAT IISAVHQLGD 360
  361 NNTTVVTVSN GVGPAGSASG GATTAASAAT EPNENITING LSPSHRQAAN NSSSSSSSAA 420
  421 TVANPLKLNT SGSADNNSTI TNATTAAGAA GAAAGTTTNG GGEFWSENPP SSASSGFSDD 480
  481 DSLAGQEGDP KPIDQIVQMV KQRGRHGLIK EYADIRNRAP EGTFLHARMR ANLTKNRYTD 540
  541 VLCYDHSRVV LAHEDGDEPS DYINANFVDG YKQKNAYIST QGPLPKTSQD FWRMIWEQHC 600
  601 LVIVMTTRVM ERGRVKCGQY WEPTEESSLE FGDYHVRTIS VECNEDYMVA SLELRNIKTD 660
  661 EIRNVSHWQF TSWPDYGVPS SAMAMLNFLQ KVREKQAQLV QGLGDTWAGH PRGPPIVVHC 720
  721 SAGIGRTGTF ITLDICISRL EDVGTADIRG TVEKIRSQRA YSIQMPDQYV FCHLALIEYA 780
  781 YSRGMLQTVD LAGFDEREPD SE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..435] PSI-BLAST 44.0 The Crystal Structure of Human Supernatant Protein Factor
    2 View Details [436..802] PSI-BLAST 93.522879 No description for 2pa5A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.78

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle