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Protein Overview: Paf-AHalpha-PA, ...

General Information:
Name(s) found: Paf-AHalpha-PB / FBpp0073976 [FlyBase]
Paf-AHalpha-PA / FBpp0073975 [FlyBase]
Description(s) found:
Found 36 descriptions.
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  • The gene Platelet-activating factor acetylhydrolase alpha is referred to in FlyBase by the symbol Dmel\Paf-AHÃ?&#142;Ã?± (CG8962, FBgn0025809). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15678042..15679612. It has the cytological map location 13E18. Based on sequence similarity, it is predicted to have molecular function</span>: 1-alkyl-2-acetylglycerophosphocholine esterase activity. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • The gene Platelet-activating factor acetylhydrolase alpha is referred to in FlyBase by the symbol Dmel\Paf-AHÃ?&#142;Ã?± (CG8962, FBgn0025809). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15678042..15679612. It has the cytological map location 13E18. Based on sequence similarity, it is predicted to have molecular function</span>: 1-alkyl-2-acetylglycerophosphocholine esterase activity. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 225 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: 1-alkyl-2-acetylglycerophosphocholine esterase activity [IDA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPCVLPTPL PDLDGDKRWH SIHRRFISDC REKDPDVIFL GDCIFETVQD TEAWNKYFAP  60
   61 LHCLNFSIRD DCTEHVLWRI ENGALDNVNP KIVVLHVGTN NVRNSAEEVA EGVLANVTKI 120
  121 RQKLPNAYIV LPSLLPRGQQ PNKLREKNAK INEVVNGLTK GLYRVQTVAI DKGLVQTDGS 180
  181 ISHHDMFDYK NLTNAGAKKI LEPLYDLLSQ ILNENEPEND LTPSE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..225] PSI-BLAST 57.221849 Platelet-activating factor acetylhydrolase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.827469072592695 bayes_pls_golite062009
  • platelet-activating factor acetyltransferase activity
    		•  0.732293103277365 bayes_pls_golite062009
  • catalytic activity
    		•  0.61713936633102 bayes_pls_golite062009
  • hydrolase activity
    		•  0.45071330223777 bayes_pls_golite062009
  • protein binding
    		•  0.222801937657621 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle