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Protein Overview: FBpp0309792, Wnt5-PA

General Information:
Name(s) found: FBpp0309792 [FlyBase]
Wnt5-PA / FBpp0074394 [FlyBase]
Description(s) found:
Found 29 descriptions.
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  • type=protein; loc=X:complement(18395871..18398885); ID=FBpp0309792; name=Wnt5-PB; parent=FBgn0010194,FBtr0343046; dbxref=FlyBase:FBpp0309792,FlyBase_Annotation_IDs:CG6407-PB; MD5=6a35cceb0b355540f9f5af0600d72106; length=1004; release=r5.56; species=Dmel; [FlyBase]
  • The gene Wnt oncogene analog 5 is referred to in FlyBase by the symbol Dmel\Wnt5 (CG6407, FBgn0010194). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:18395573..18399436. It has the cytological map location 17B6-17C1. There is experimental evidence that it has the molecular function</span>: receptor binding. There is experimental evidence that it is involved in the biological process</span>: axon guidance; axon extension; salivary gland morphogenesis. 17 alleles are reported. The phenotypes of these alleles are annotated with: commissure; embryonic salivary gland; intermediate longitudinal fascicle; ventral nerve cord; lateral longitudinal fascicle; anterior commissure. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1004 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [IEA][NAS][TAS]
    Biological Process: negative chemotaxis [TAS]
    axon extension [IMP]
    Wnt receptor signaling pathway, calcium modulating pathway [ISS]
    Wnt receptor signaling pathway [NAS]
    axon guidance [IGI][IMP][TAS]
    salivary gland morphogenesis [IMP]
    Molecular Function: growth factor activity [ISS]
    signal transducer activity [ISS]
    receptor binding [IPI][ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSCYRKRHFL LWLLRAVCML HLTARGAYAT VGLQGVPTWI YLGLKSPFIE FGNQVEQLAN  60
   61 SSIPLNMTKD EQANMHQEGL RKLGTFIKPV DLRDSETGFV KADLTKRLVF DRPNNITSRP 120
  121 IHPIQEEMDQ KQIILLDEDT DENGLPASLT DEDRKFIVPM ALKNISPDPR WAATTPSPSA 180
  181 LQPNAKAIST IVPSPLAQVE GDPTSNIDDL KKHILFLHNM TKTNSNFESK FVKFPSLQKD 240
  241 KAKTSGAGGS PPNPKRPQRP IHQYSAPIAP PTPKVPAPDG GGVGGAAYNP GEQPIGGYYQ 300
  301 NEELANNQSL LKPTDTDSHP AAGGSSHGQK NPSEPQVILL NETLSTETSI EADRSPSINQ 360
  361 PKAGSPARTT KRPPCLRNPE SPKCIRQRRR EEQQRQRERD EWFRGQSQYM QPRFEPIIQT 420
  421 INNTKRFAVS IEIPDSFKVS SEGSDGELLS RVERSQPSIS SSSSSSSSSS RKIMPDYIKV 480
  481 SMENNTSVTD YFKHDVVMTS ADVASDREFL IKNMEEHGGA GSANSHHNDT TPTADAYSET 540
  541 IDLNPNNCYS AIGLSNSQKK QCVKHTSVMP AISRGARAAI QECQFQFKNR RWNCSTTNDE 600
  601 TVFGPMTSLA APEMAFIHAL AAATVTSFIA RACRDGQLAS CSCSRGSRPK QLHDDWKWGG 660
  661 CGDNLEFAYK FATDFIDSRE KETNRETRGV KRKREEINKN RMHSDDTNAF NIGIKRNKNV 720
  721 DAKNDTSLVV RNVRKSTEAE NSHILNENFD QHLLELEQRI TKEILTSKID EEEMIKLQEK 780
  781 IKQEIVNTKF FKGEQQPRKK KRKNQRAAAD APAYPRNGIK ESYKDGGILP RSTATVKARS 840
  841 LMNLHNNEAG RRAVIKKARI TCKCHGVSGS CSLITCWQQL SSIREIGDYL REKYEGATKV 900
  901 KINKRGRLQI KDLQFKVPTA HDLIYLDESP DWCRNSYALH WPGTHGRVCH KNSSGLESCA 960
  961 ILCCGRGYNT KNIIVNERCN CKFHWCCQVK CEVCTKVLEE HTCK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..95] deduced N/A No confident structure predictions are available.
    2 View Details [96..524] FFAS03 2.02 THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA
    3 View Details [525..607] MSA 5.188987 View MSA. No confident structure predictions are available.
    4 View Details [608..692] deduced N/A No confident structure predictions are available.
    5 View Details [693..869] MSA 7.203983 View MSA. No confident structure predictions are available.
    6 View Details [870..1004] MSA 28.144978 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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