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Protein Overview: SPBC25H2.03

General Information:
Name(s) found: SPBC25H2.03 [Sanger Pombe]
Description(s) found:
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  • gi|8928504|sp|P87145.1|VAC14_SCHPO RecName: Full=Protein VAC14 homolog [NCBI NR]
  • pir||T39998 hypothetical protein SPBC25H2.03 - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|2104452|emb|CAB08779.1| vacuolar protein involved in phosphoinositide metabolism [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19113155|ref|NP_596363.1| vacuolar protein involved in phosphoinositide metabolism [Schizosaccharomyces pombe] [NCBI NR]
  • vacuolar protein involved in phosphoinositide metabolism [Sanger Pombe]
  • HEAT repeat protein C25H2.03 - Schizosaccharomyces pombe (Fission yeast) [Swiss-Prot]
  • Protein VAC14 homolog OS=Schizosaccharomyces pombe GN=SPBC25H2.03 PE=2 SV=1 [Swiss-Prot]
  • HYPOTHETICAL PROTEIN; SIMILAR TO S. CEREVISIAE YLR386W: P87145; [pompepVF.fasta]
  • Hypothetical protein C25H2.03 in chromosome II [pompep4896]
  • |||HEAT repeat [pompepnew.fasta]
  • |||HEAT repeat|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • HEAT repeat; involved in phospholipid metabolism (predicted); involved in vacuole inheritance (PMID 9372916) (predicted); involved in stress-induced increase of phosphatidylinositol 3,5-bisphosphate (predicted) (PMID 11889142); localization vacuole; simil [nrdb_11152004_Chlamydomonas]
  • (P87145) Hypothetical protein C25H2.03 in chromosome II [pompep4896_normal_reversed]
  • |||vacuolar protein involved in phosphoinositide metabolism|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPBC25H2.03 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPBC25H2.03 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • |||vacuolar protein involved in phosphoinositide metabolism |Schizosaccharomyces pombe|chr 2|||Manual [Other_S_Pombe_12-15-2011_reversed.fasta]
  • Protein VAC14 homolog OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC25H2.03 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 811 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    fungal-type vacuole membrane [ISSLink to PubMed article]
    protein complex [RCALink to PubMed article]
    extrinsic to membrane [IEA]
    Biological Process: vacuole inheritance [ISSLink to PubMed article]
    phosphoinositide-mediated signaling [NASLink to PubMed article]
    phosphoinositide metabolic process [NASLink to PubMed article]
    phospholipid metabolic process [ISSLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDNLLVRGLT HKLYDKRKAT AYELERVVKG YLENDETEKI RAVISQLAND FVYSPARGPN  60
   61 ATFGGLIGLA AVAIALGPKI DSYMESILLP VLYCFNDSDS KIRYYACESM YNIGKVAKGE 120
  121 VFRYFNLIFD VLCKLFADTE ITVKNGAELL DRLIKDIVMQ QAATYMSSAE DIKNFKEGPV 180
  181 SSSIQDVPVM STEQPRMHTF SLSELVPLLS ERLYVINPNT RMFLVSWIRL LDSIPDLEFI 240
  241 SYLPFLLDGL MNYLSDPNES IRIVTSNCLY DFLREIQKIA KVKYHILQRD EESEPDFFDS 300
  301 MVRRNMSDAE LKEISDYVES SLRDGSFILE AHIQIDYKRI LEIIIDHLGS SVPLIQEKAL 360
  361 KWLFEFIYIA PKDVLLQIPK VLENLLPLMS NDENMRQSAK DLSQNLVILV SKIMDIEFSG 420
  421 SETNNKDNSL SVDFRSLIEV LQKLLSNDNE ETRLCALEWV LLLQRRTGGK LINMHDPIFQ 480
  481 TLLLQLSDPS DLVVSRTLEL LAHIAISHKS VNLVPFLKSL LQMFAEDRKF LNSRGNLIIR 540
  541 QLCNYIEGER VYTSFAGILE TEENLELASI MVEVLNNNLF TAPELYDLRK KLKQSAPKLQ 600
  601 NIFTTLYTAW CHNSIAVFSL CLLSQNYEHA ANLLSVFAEI EFNIDMLIQL DKLVQLIESP 660
  661 VFTYMRLQLL EPEKYPYLHK ALYGILMLLP QSSAFRTLRD RLQCSSTPRT NTILANERLP 720
  721 RSRRDDPYWT DLLERLKAVQ LSHQNNYREP IRATRLALAG ALPSTPTATT ISTTTSASGI 780
  781 TTTASNSRDS FITRLPPTAA LSTGARKKPK Q

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..579] PSI-BLAST 73.39794 No description for 2h4mA was found.
    2 View Details [580..672] PSI-BLAST 34.221849 Crystal Structure of The Cand1-Cul1-Roc1 Complex
    3 View Details [673..811] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.62

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle