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Protein Overview: tag-312

General Information:
Name(s) found: tag-312 / CE27102 [WormBase]
Description(s) found:
Found 21 descriptions.
SHOW ALL
  • WBGene00016344 locus:tag-312 Ras and EF-hand domain-containing protein homolog status:Partially_confirmed UniProt:Q22908 protein_id:CCD66473.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 656 amino acids

    Gene Ontology:
    Cellular Component: ribosome [IEALink to PubMed article]
    intracellular [IEALink to PubMed article]
    Biological Process: nucleocytoplasmic transport [IEALink to PubMed article]
    signal transduction [IEALink to PubMed article]
    small GTPase mediated signal transduction [IEALink to PubMed article]
    protein transport [IEALink to PubMed article]
    intracellular protein transport [IEALink to PubMed article]
    translation [IEALink to PubMed article]
    Molecular Function: GTP binding [IEALink to PubMed article]
    protein binding [IEALink to PubMed article]
    structural constituent of ribosome [IEALink to PubMed article]
    GTPase activity [IEALink to PubMed article]
    calcium ion binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKPEVENLF SLCDSESKGY LTMEDLRKVC PQLDDNDLRF IFTELDQDGS GKIEKLEFLR  60
   61 GFQDTVQHGE SHGLNGMQRR ASVAVEDPPM FLRDEQMFDS ESDSTSSRPA IRVFDEEHYH 120
  121 SESDTNINID FSVPCQEEVL VLYEQLQSSG VPALLRKFER VVGSFHKELS EKKHENERLQ 180
  181 RIYASEREMY NRRMEEMESE VDQQLELTEM KARQEERDRL TKEKEEMRQR MSDEMSEMRN 240
  241 NIERLQKMEK ALERENERLN HQKELSDKLK VVNEENNDLR QNLAENHLEL AMIKSELAQV 300
  301 RCEFDQKQDE LSARRGILFQ LEPINSLSSS DQASHATEES ESVRKQLQLL FDANRKLHET 360
  361 NESLRDALDS RASVLRQFNL RTPSPGLLSS NRNSVENFQT STNVFRSVPL HAISTEEQGT 420
  421 IFGTIEEKTS LILDDAHSLQ GLDTPGDLMG LNDANGPAER TFRIVMCGDA AVGKSSFVMR 480
  481 VIRRQFTNQL PSTLGVDFHV KTVNVDGRNV ALQLWDTAGQ ERFRSLCKSY FRRADGAILV 540
  541 YDVCAEQSFL RVRDWIETIK ESTERSIPII LVGNKVDMRI STPGSVAKTD GASMAAAMGV 600
  601 LFMETSALDG SNIDNAMLAL TRELMAVEDV EIRSTGVVLN PAVAKKGGCF SKCRGS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..323] PSI-BLAST 21.522879 Heavy meromyosin subfragment
    2 View Details [324..453] PSI-BLAST 8.522879 Tropomyosin
    3 View Details [454..656] PSI-BLAST 48.522879 Crystal structure of human RAB1A in complex with GDP

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • GTPase activity
    		•  4.52394549632777 bayes_pls_golite062009
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  4.26230696590213 bayes_pls_golite062009
  • motor activity
    		•  4.04927796049806 bayes_pls_golite062009
  • microtubule motor activity
    		•  3.91769993918004 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  3.35170865169069 bayes_pls_golite062009
  • actin binding
    		•  3.33639699088484 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  3.23143315078113 bayes_pls_golite062009
  • microfilament motor activity
    		•  3.17800963620802 bayes_pls_golite062009
  • signal recognition particle binding
    		•  3.10924684520019 bayes_pls_golite062009
  • transporter activity
    		•  3.10463051760206 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.95886887664984 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.95079405147356 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.87427509025394 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.85499564954033 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.85178667290149 bayes_pls_golite062009
  • hydrolase activity
    		•  2.73675310079844 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  2.72462789867829 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  2.61775212528604 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  2.61467977505707 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  2.58603227794045 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  2.57552435627908 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  2.57107347424517 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  2.57054427875021 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.51683451033161 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  2.50494515048649 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  2.43862163407966 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.4101693596493 bayes_pls_golite062009
  • ATPase activity
    		•  2.39535714892224 bayes_pls_golite062009
  • G-protein coupled receptor activity
    		•  2.3505608190884 bayes_pls_golite062009
  • protein-DNA loading ATPase activity
    		•  2.29933364503114 bayes_pls_golite062009
  • DNA helicase activity
    		•  2.2817164193758 bayes_pls_golite062009
  • DNA clamp loader activity
    		•  2.25735202908071 bayes_pls_golite062009
  • actin filament binding
    		•  2.24723363507804 bayes_pls_golite062009
  • DNA binding
    		•  2.12258000781149 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.09345198747025 bayes_pls_golite062009
  • ribonucleoprotein binding
    		•  2.04103162399905 bayes_pls_golite062009
  • proton-transporting ATPase activity, rotational mechanism
    		•  1.95782378818812 bayes_pls_golite062009
  • tubulin binding
    		•  1.92557767696163 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.91091452720653 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  1.89320355239381 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  1.88721318481223 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  1.88455339138556 bayes_pls_golite062009
  • GTP binding
    		•  1.87900088157196 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.85943679361938 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.85937484083653 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.8521191028835 bayes_pls_golite062009
  • nucleotide binding
    		•  1.84603132945448 bayes_pls_golite062009
  • microtubule binding
    		•  1.84561785126784 bayes_pls_golite062009
  • kinase activity
    		•  1.80889641165674 bayes_pls_golite062009
  • protein transporter activity
    		•  1.71214667007262 bayes_pls_golite062009
  • helicase activity
    		•  1.70242731830224 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.60386625568858 bayes_pls_golite062009
  • actin-dependent ATPase activity
    		•  1.58897222423517 bayes_pls_golite062009
  • ATP binding
    		•  1.5859264197035 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.56325751172863 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.55520429131224 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.53158018507951 bayes_pls_golite062009
  • apolipoprotein receptor activity
    		•  1.52496551152043 bayes_pls_golite062009
  • syntaxin-13 binding
    		•  1.52496551152043 bayes_pls_golite062009
  • apolipoprotein A-I binding
    		•  1.52496551152043 bayes_pls_golite062009
  • apolipoprotein A-I receptor activity
    		•  1.52496551152043 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.47858140861683 bayes_pls_golite062009
  • RNA helicase activity
    		•  1.42791449104435 bayes_pls_golite062009
  • RNA-dependent ATPase activity
    		•  1.39335733374328 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
    		•  1.36724390116598 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  1.26314334516725 bayes_pls_golite062009
  • protein binding
    		•  1.22129154759482 bayes_pls_golite062009
  • receptor activity
    		•  1.20313362488821 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  1.19311444180077 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  1.19311444180077 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.14475274823167 bayes_pls_golite062009
  • signal transducer activity
    		•  1.13474466330485 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.13474466330485 bayes_pls_golite062009
  • protein kinase activity
    		•  1.12864835254143 bayes_pls_golite062009
  • ADP binding
    		•  1.10601354993582 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.977237423302079 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
    		•  0.971476020912368 bayes_pls_golite062009
  • DNA polymerase activity
    		•  0.928091843881235 bayes_pls_golite062009
  • GBD domain binding
    		•  0.914270985726459 bayes_pls_golite062009
  • transcription activator activity
    		•  0.889929694023098 bayes_pls_golite062009
  • transcription factor activity
    		•  0.887108427603557 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  0.876296121718575 bayes_pls_golite062009
  • transferase activity
    		•  0.871779313294914 bayes_pls_golite062009
  • structural molecule activity
    		•  0.86514677273731 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.862685397469217 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.793781356852064 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.782430219754236 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  0.763810597209294 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  0.763810597209294 bayes_pls_golite062009
  • steroid hormone receptor binding
    		•  0.647625526012423 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  0.63002958837536 bayes_pls_golite062009
  • cell surface binding
    		•  0.618263399939881 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.6071273686445 bayes_pls_golite062009
  • telomeric DNA binding
    		•  0.60010060632866 bayes_pls_golite062009
  • sterol transporter activity
    		•  0.57614280790431 bayes_pls_golite062009
  • plus-end-directed microtubule motor activity
    		•  0.567883621045161 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.557919489256916 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.543891899378373 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  0.46552249844591 bayes_pls_golite062009
    		• 0.442119153778711 bayes_pls_golite062009
  • structural constituent of muscle
    		•  0.411137875876923 bayes_pls_golite062009
  • drug transmembrane transporter activity
    		•  0.38711726712063 bayes_pls_golite062009
  • monosaccharide transmembrane transporter activity
    		•  0.360241187539348 bayes_pls_golite062009
  • hormone receptor binding
    		•  0.351501100511918 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.345873656782869 bayes_pls_golite062009
  • peptide binding
    		•  0.304703625340488 bayes_pls_golite062009
  • translation regulator activity
    		•  0.29096092258568 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.274994961137851 bayes_pls_golite062009
  • myosin binding
    		•  0.274885859454447 bayes_pls_golite062009
  • DNA strand annealing activity
    		•  0.270268254152179 bayes_pls_golite062009
  • nuclear hormone receptor binding
    		•  0.246160342138071 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.243902356228423 bayes_pls_golite062009
  • nucleobase, nucleoside, nucleotide kinase activity
    		•  0.12351419478929 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  0.123304946374679 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  0.0775601177068852 bayes_pls_golite062009
  • RNA binding
    		•  0.0261282189186349 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.0111338193708552 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle