Protein Overview: him-6

General Information:
Name(s) found:	him-6 / CE31724 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00001865 locus:him-6 Bloom syndrome protein homolog status:Confirmed UniProt:O18017 protein_id:CAB05609.2 [WormBase] gi\|28201770\|sp\|O18017.2\|BLM_CAEEL RecName: Full=Bloom syndrome protein homolog; AltName: Full=RecQ helicase homolog; AltName: Full=High incidence of males protein 6 [NCBI NR] gi\|25145561\|ref\|NP_502390.2\| High Incidence of Males (increased X chromosome loss) family member (him-6) [Caenorhabditis elegans] [NCBI NR] gi\|22859109\|emb\|CAB05609.2\| C. elegans protein T04A11.6, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|20853750\|gb\|AAM26298.1\| RecQ helicase [Caenorhabditis elegans] [NCBI NR] Bloom syndrome protein homolog OS=Caenorhabditis elegans GN=him-6 PE=2 SV=2 [Swiss-Prot] [wormpep88.fasta] CE31724 WBGene00001865 locus:him-6 helicase status:Confirmed SW:O18017 protein_id:CAB05609.2 [wormpep150.fasta] 31724 WBGene00001865 locus:him-6 helicase status:Confirmed SW:O18017 protein_id:CAB05609.2 [wormpep130-phg-ecoli-orf-rand.fasta] high Incidence of Males due to increased X chromosome loss HIM-6, human BLooM syndrome related, RecQ helicase, meiotic chromosome disjunction and recombination factor (110.7 kD) (him-6) [Caenorhabditis elegans]gi\|22859109\|emb\|CAB05609.2\| Hypothetical pro [nrdb_11152004_Chlamydomonas] locus:him-6 helicase status:Confirmed SW:O18017 protein_id:CAB05609.2 [wormpep115.fasta.reversed] CE31724 WBGene00001865 locus:him-6 helicase status:Confirmed UniProt:O18017 protein_id:CAB05609.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE31724 WBGene00001865 locus:him-6 helicase status:Confirmed UniProt:O18017 protein_id:CAB05609.2\| [wormORF-contam.fasta] Bloom syndrome protein homolog (RecQ helicase homolog) (High incidence of males protein 6) [nr-271106-contam.fasta] Hypothetical protein T04A11.6 [Caenorhabditis elegans] [nr-271106-contam.fasta] T04A11.6 [Caenorhabditis elegans] [nr-271106-contam.fasta] RecQ helicase [Caenorhabditis elegans] [nr-271106-contam.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE31724 WBGene00001865 locus:him-6 status:Confirmed UniProt:O18017 protein_id:CAB05609.2 Bloom syndrome protein homolog [wormpep246-ecoli-contam.fasta]
Organism:	Caenorhabditis elegans
Length:	988 amino acids
Gene Ontology:
Cellular Component:	intracellular [IEA]
Biological Process:	DNA recombination [IEA] SOS response [IEA]
Molecular Function:	nucleic acid binding [IEA] ATP binding [IEA] ATP-dependent helicase activity [IEA] helicase activity [IEA] ATP-dependent DNA helicase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIKNREIEVA PPRRTIQFGG YTFVEPDLNF KAPIFSCCGS IRDPSCEERE EEYIDNGHDE  60
   61 EPPVEVNRIQ ESTSFDEPVS SPPRYRPSEN PGPSSSSYEP GHYSFNEYQQ FPSRPQKRLV 120
  121 DPPIVDLDEE PPIVDLDDSF DNFHVGSTSE EVVSGDIAPE EEEEEGHDSF DDFESVPAQP 180
  181 PSKNTLASLQ KSDSEIALNQ QRHDMHGRFR GFLQDDSEEF SDEVGLLGAD MNKELYDTLK 240
  241 SKFGFNQFRH RQKQCILSTL MGHDTFVLMP TGAGKSLCYQ LPAVILPGVT VVVSPLRSLI 300
  301 EDQKMKMKEL GIGCEALTAD LGAPAQEKIY AELGSGNPSI KLLYVTPEKI SASGRLNSVF 360
  361 FDLHRRGLLA RFVIDEAHCV SQWGHDFRPD YTKLSSLREK YANPPVPIIA LTATATPKIV 420
  421 TDARDHLKMQ NSKLFISSFV RDNLKYDLIP KAARSLINVV EKMKQLYPGK SGIVYCLSRK 480
  481 ECETVQMMLT KAGLSAEVYH AGLNDNLRVS VQRSWIANKF DVICATIAFG MGIDKPDVRF 540
  541 VIHYSLPKSI EGYYQETGRA GRDGMPSYCL MLYSYHDSIR LRRMIEEGNT TTGVRSMHLN 600
  601 NVLQVVAYCE NVSVCRRKML VEHFGEVYDE QSCRNSKTPC DICERQRKNA EAIRLFDVST 660
  661 DALSILKCLP RMQKATLKYI SELYRGALIK KSQEQAMRLG HTKLPFYSKG QGMSEQDALR 720
  721 FVRKLVIEGY IHERLYSVPN QAAAVFAYAE LTEAGRDLAN GKKTAKVYLH IVTCERKRKN 780
  781 AGLIELSNMN IVSEAQALKE RHMVKHGDVF TRCLQDLTHL ITAVAESSGL SGPYSIVSRE 840
  841 GIEQIAALLP RTNSDLLRID SMTQIKVTKY GRLIMELLAT YWKQVDEREE EEMRNQLDKL 900
  901 KSGEIVMGGF ATLQSDPGFP SVPYMKPLGG GGGCRGRGKK RAFSGFSSGR ATKKPRATAP 960
  961 SARGKTSGRG GAKPATSLKR NMYPATSM

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: him-6

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: