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Protein Overview: dpy-23

General Information:
Name(s) found: dpy-23 / CE33813 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00001082 locus:dpy-23 AP-2 complex subunit mu status:Confirmed UniProt:P35603 protein_id:CCD68418.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 441 amino acids

    Gene Ontology:
    Cellular Component: membrane coat [IEALink to PubMed article]
    clathrin adaptor complex [IEALink to PubMed article]
    Biological Process: molting cycle, protein-based cuticle [IMPLink to PubMed article]
    vesicle-mediated transport [IEALink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    protein complex assembly [IEALink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    intracellular protein transport [IEALink to PubMed article]
    growth [IMPLink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed article]
    Molecular Function: protein binding [IEALink to PubMed article]
    protein transporter activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIGGLFVYNH KGEVLISRIY RDDVTRNAVD AFRVNVIHAR QQVRSPVTNM ARTSFFHVKR  60
   61 GNVWICAVTR QNVNAAMVFE FLKRFADTMQ SYFGKLNEEN VKNNFVLIYE LLDEILDFGY 120
  121 PQNTDPGVLK TFITQQGVRT ADAPVPVTKE EQSQITSQVT GQIGWRREGI KYRRNELFLD 180
  181 VIEYVNLLMN QQGQVLSAHV AGKVAMKSYL SGMPECKFGI NDKITIEGKS KPGSDDPNKA 240
  241 SRAAVAIDDC QFHQCVKLTK FETEHAISFI PPDGEYELMR YRTTKDIQLP FRVIPLVREV 300
  301 SRNKMEVKVV VKSNFKPSLL AQKLEVRIPT PPNTSGVQLI CMKGKAKYKA GENAIVWKIK 360
  361 RMAGMKESQI SAEIDLLSTG NVEKKKWNRP PVSMNFEVPF APSGLKVRYL KVFEPKLNYS 420
  421 DHDVIKWVRY IGRSGLYETR C

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..441] PSI-BLAST 127.0 MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH NON-CANONICAL INTERNALIZATION PEPTIDE VEDYEQGLSG


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle