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Protein Overview: GSH1_ARATH

General Information:
Name(s) found: GSH1_ARATH [Swiss-Prot]
Description(s) found:
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  • pir||T05142 glutamate-cysteine ligase (EC 6.3.2.2) precursor, chloroplast - Arabidopsis thaliana [NCBI NR]
  • gi|7269157|emb|CAB79265.1| gamma-glutamylcysteine synthetase [Arabidopsis thaliana] [NCBI NR]
  • gi|4262277|gb|AAD14544.1| gamma-glutamylcysteine synthetase [Arabidopsis thaliana] [NCBI NR]
  • gi|3292836|emb|CAA19826.1| gamma-glutamylcysteine synthetase [Arabidopsis thaliana] [NCBI NR]
  • gi|23506099|gb|AAN28909.1| At4g23100/F7H19_290 [Arabidopsis thaliana] [NCBI NR]
  • gi|16930445|gb|AAL31908.1|AF419576_1 AT4g23100/F7H19_290 [Arabidopsis thaliana] [NCBI NR]
  • gi|15236390|ref|NP_194041.1| GSH1 (GLUTAMATE-CYSTEINE LIGASE); glutamate-cysteine ligase [Arabidopsis thaliana] [NCBI NR]
  • gi|12644273|sp|P46309.2|GSH1_ARATH RecName: Full=Glutamate--cysteine ligase, chloroplastic; AltName: Full=Gamma-glutamylcysteine synthetase; AltName: Full=Gamma-ECS; Short=GCS; AltName: Full=Protein cadmium-sensitive 2; AltName: Full=Protein phytoalexin-d [NCBI NR]
  • Glutamate--cysteine ligase, chloroplastic OS=Arabidopsis thaliana GN=GSH1 PE=1 SV=2 [Swiss-Prot]
  • (P46309) Glutamate--cysteine ligase, chloroplast precursor (EC 6.3.2.2) (Gamma-glutamylcysteine synthetase) (Gamma-ECS) (GCS) [athaliana3702.FASTAC.txt]
  • At4g23100/F7H19_290 [Arabidopsis thaliana]gi|7269157|emb|CAB79265.1| gamma-glutamylcysteine synthetase [Arabidopsis thaliana]gi|3292836|emb|CAA19826.1| gamma-glutamylcysteine synthetase [Arabidopsis thaliana]gi|16930445|gb|AAL31908.1| AT4g23100/F7H19_2 [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Glutamate--cysteine ligase, chloroplast precursor [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: GSH1, CAD2, PAD2, RML1 | RML1 (ROOT MERISTEMLESS 1); glutamate-cysteine ligase | chr4:12103469-12106762 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • Glutamate--cysteine ligase, chloroplast precursor (Gamma-glutamylcysteine synthetase) (Gamma-ECS) (GCS) [nr-271106-contam.fasta]
  • AT4g23100/F7H19_290 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • gamma-glutamylcysteine synthetase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • RML1 (ROOT MERISTEMLESS 1) [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • At4g23100/F7H19_290 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: RML1, PAD2, GSH1, CAD2, ATECS1, GSHA | glutamate-cysteine ligase | chr4:12103458-12106751 REVERSE LENGTH=522 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
  • | Symbols: GSH1 | glutamate-cysteine ligase | chr4:12103458-12106751 REVERSE LENGTH=522 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 522 amino acids

    Gene Ontology:
    Cellular Component: chloroplast stroma [IDA]
    chloroplast [IDA]
    Biological Process: response to ozone [IEP]
    glutathione biosynthetic process [IDA][IMP][TAS]
    response to jasmonic acid stimulus [IEP]
    response to cadmium ion [IEP][IMP]
    defense response to bacterium [IMP]
    indole phytoalexin biosynthetic process [IMP]
    defense response to insect [IMP]
    callose deposition in cell wall during defense response [IMP]
    defense response to bacterium, incompatible interaction [IMP]
    response to heat [IMP]
    flower development [IMP]
    glucosinolate biosynthetic process [IMP]
    defense response to fungus [IMP]
    Molecular Function: glutamate-cysteine ligase activity [IDA][IMP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALLSQAGGS YTVVPSGVCS KAGTKAVVSG GVRNLDVLRM KEAFGSSYSR SLSTKSMLLH  60
   61 SVKRSKRGHQ LIVAASPPTE EAVVATEPLT REDLIAYLAS GCKTKDKYRI GTEHEKFGFE 120
  121 VNTLRPMKYD QIAELLNGIA ERFEWEKVME GDKIIGLKQG KQSISLEPGG QFELSGAPLE 180
  181 TLHQTCAEVN SHLYQVKAVA EEMGIGFLGI GFQPKWRRED IPIMPKGRYD IMRNYMPKVG 240
  241 TLGLDMMLRT CTVQVNLDFS SEADMIRKFR AGLALQPIAT ALFANSPFTE GKPNGFLSMR 300
  301 SHIWTDTDKD RTGMLPFVFD DSFGFEQYVD YALDVPMYFA YRKNKYIDCT GMTFRQFLAG 360
  361 KLPCLPGELP SYNDWENHLT TIFPEVRLKR YLEMRGADGG PWRRLCALPA FWVGLLYDDD 420
  421 SLQAILDLTA DWTPAEREML RNKVPVTGLK TPFRDGLLKH VAEDVLKLAK DGLERRGYKE 480
  481 AGFLNAVDEV VRTGVTPAEK LLEMYNGEWG QSVDPVFEEL LY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..522] PSI-BLAST 158.0 No description for 2gwcA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.83

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle