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Protein Overview: ISPE_ARATH

General Information:
Name(s) found: ISPE_ARATH [Swiss-Prot]
Description(s) found:
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  • pir||T02642 probable ripening-associated protein [imported] - Arabidopsis thaliana [NCBI NR]
  • gi|7387807|sp|O81014.1|ISPE_ARATH RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase; Short=CDPMEK; Short=CMK; Flags: Precursor [NCBI NR]
  • gi|3426035|gb|AAC32234.1| putative ripening-associated protein [Arabidopsis thaliana] [NCBI NR]
  • gi|23198000|gb|AAN15527.1| putative ripening-associated protein [Arabidopsis thaliana] [NCBI NR]
  • gi|22531112|gb|AAM97060.1| putative ripening-associated protein [Arabidopsis thaliana] [NCBI NR]
  • gi|15225820|ref|NP_180261.1| ATCDPMEK (4-(CYTIDINE 5'-PHOSPHO)-2-C-METHYL-D-ERITHRITOL KINASE); 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase [Arabidopsis thaliana] [NCBI NR]
  • gi|12697585|dbj|BAB21593.1| 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase [Arabidopsis thaliana] [NCBI NR]
  • 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic OS=Arabidopsis thaliana GN=ISPE PE=2 SV=1 [Swiss-Prot]
  • (O81014) 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplast precursor (EC 2.7.1.148) (CMK) (4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase) (CDPMEK) [athaliana3702.FASTAC.txt]
  • putative ripening-associated protein [Arabidopsis thaliana]gi|12697585|dbj|BAB21593.1| 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase [Arabidopsis thaliana]gi|22531112|gb|AAM97060.1| putative ripening-associated protein [Arabidopsis thaliana]gi [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplast precursor [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: PDE277, ISPE, ATCDPMEK | ATCDPMEK (PIGMENT DEFECTIVE 277); 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase | chr2:11498907-11501307 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • putative ripening-associated protein [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • ATCDPMEK; ATP binding / kinase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplast precursor (CMK) (4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase) (CDPMEK) [nr-271106-contam.fasta]
  • 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: ATCDPMEK, PDE277, ISPE, CDPMEK | 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase | chr2:11491829-11494229 REVERSE LENGTH=383 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 383 amino acids

    Gene Ontology:
    Cellular Component: chloroplast [IDA]
    Biological Process: NONE FOUND
    Molecular Function: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATASPPFIS TLSFTHSSFK TSSSSSFSPK LLRPLLSFSV KASRKQVEIV FDPDERLNKI  60
   61 GDDVDKEAPL SRLKLFSPCK INVFLRITGK REDGFHDLAS LFHVISLGDT IKFSLSPSKS 120
  121 KDRLSTNVQG VPVDGRNLII KALNLYRKKT GSNRFFWIHL DKKVPTGAGL GGGSSNAATA 180
  181 LWAANELNGG LVTENELQDW SSEIGSDIPF FFSHGAAYCT GRGEIVQDLP PPFPLDLPMV 240
  241 LIKPREACST AEVYKRLRLD QTSNINPLTL LENVTSNGVS QSICVNDLEP PAFSVLPSLK 300
  301 RLKQRIIASG RGEYDAVFMS GSGSTIIGIG SPDPPQFIYD DEEYKNVFLS EANFMTREAN 360
  361 EWYKEPASAN ATTSSAESRM DFQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..69] PSI-BLAST 18.0 Crystal structure of Saccharomyces cerevisiae Galactokinase in complex with galactose and Mg:AMPPNP
    2 View Details [70..383] PSI-BLAST 61.154902 Ternary complex of 4-diphosphocytidyl-2C-methyl-D-erythritol kinase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity
    		•  1.9881460462076 bayes_pls_golite062009
  • catalytic activity
    		•  1.20658247466773 bayes_pls_golite062009
  • diphosphomevalonate decarboxylase activity
    		•  1.0502744466494 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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