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Protein Overview: AUR1_ARATH

General Information:
Name(s) found: AUR1_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|75335736|sp|Q9M077.1|AUR1_ARATH RecName: Full=Serine/threonine-protein kinase Aurora-1; Short=AtAur1; AltName: Full=Aurora-like kinase 1 [NCBI NR]
  • pir||T10690 serine/threonine-specific protein kinase homolog T16I18.40 - Arabidopsis thaliana [NCBI NR]
  • gi|7270230|emb|CAB80000.1| putative serine/threonine protein kinase [Arabidopsis thaliana] [NCBI NR]
  • gi|67845859|dbj|BAE00019.1| Aurora kinase [Arabidopsis thaliana] [NCBI NR]
  • gi|62320564|dbj|BAD95178.1| putative serine/threonine protein kinase [Arabidopsis thaliana] [NCBI NR]
  • gi|55467118|emb|CAH69532.1| aurora-like kinase 1 [Arabidopsis thaliana] [NCBI NR]
  • gi|15233958|ref|NP_195009.1| AtAUR1 (ATAURORA1); histone kinase(H3-S10 specific) / kinase/ protein serine/threonine kinase [Arabidopsis thaliana] [NCBI NR]
  • Serine/threonine-protein kinase Aurora-1 OS=Arabidopsis thaliana GN=AUR1 PE=1 SV=1 [Swiss-Prot]
  • (Q9M077) Putative serine/threonine protein kinase [athaliana3702.FASTAC.txt]
  • aurora-like kinase 1 [Arabidopsis thaliana]gi|7270230|emb|CAB80000.1| putative serine/threonine protein kinase [Arabidopsis thaliana]gi|15233958|ref|NP_195009.1| protein kinase, putative [Arabidopsis thaliana]gi|7434310|pir||T10690 serine/threonine-spe [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Encodes a member of a family of Ser/Thr kinases whose activities peak during cell division [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: ATAUR1 | ATAUR1 (ATAURORA1); histone serine kinase(H3-S10 specific) / kinase/ protein serine/threonine kinase | chr4:15842561-15844358 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • putative serine/threonine protein kinase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • Aurora kinase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • aurora-like kinase 1 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • kinase/ protein serine/threonine kinase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: AtAUR1, AUR1 | ataurora1 | chr4:15842557-15844354 FORWARD LENGTH=294 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 294 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    spindle [IDA]
    nucleolus [IDA]
    Biological Process: histone phosphorylation [IDA]
    Molecular Function: histone kinase activity (H3-S10 specific) [IDA]
    protein serine/threonine kinase activity [IDA]
    kinase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAIPTETQHQ EKEASDASAA AAQKRWTLSD FDIGKPLGRG KFGHVYLARE KRSNHVVALK  60
   61 VLFKSQLQQS QVEHQLRREV EIQSHLRHPN ILRLYGYFYD QKRVYLILEY AARGELYKDL 120
  121 QKCKYFSERR AATYVASLAR ALIYCHGKHV IHRDIKPENL LIGAQGELKI ADFGWSVHTF 180
  181 NRRRTMCGTL DYLPPEMVES VEHDASVDIW SLGILCYEFL YGVPPFEAME HSDTYRRIVQ 240
  241 VDLKFPPKPI ISASAKDLIS QMLVKESSQR LPLHKLLEHP WIVQNADPSG IYRV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..294] PSI-BLAST 72.30103 No description for 2j4zA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein kinase activity
    		•  5.4586557943719 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  5.04467222534257 bayes_pls_golite062009
  • kinase activity
    		•  4.85903980916957 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.63692708178478 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  4.46381887831481 bayes_pls_golite062009
  • transferase activity
    		•  3.26787750561728 bayes_pls_golite062009
  • binding
    		•  2.74863538127007 bayes_pls_golite062009
  • ATP binding
    		•  1.97600611746091 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.93596671856664 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.90928021591891 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.65732943334212 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.65726906484847 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.63763394711025 bayes_pls_golite062009
  • nucleotide binding
    		•  1.63195828048121 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  1.3898059094397 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
    		•  1.38496328649031 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  1.27291233344322 bayes_pls_golite062009
  • protein binding
    		•  1.22565748038754 bayes_pls_golite062009
  • catalytic activity
    		•  1.21655087018101 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.794058505655489 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.775404673285876 bayes_pls_golite062009
  • DNA binding
    		•  0.714163549867672 bayes_pls_golite062009
  • transcription factor activity
    		•  0.563262875317016 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
    		•  0.499492353295369 bayes_pls_golite062009
  • kinase binding
    		•  0.443916188551908 bayes_pls_golite062009
  • magnesium ion binding
    		•  0.393328812780268 bayes_pls_golite062009
  • protein kinase binding
    		•  0.285611963740145 bayes_pls_golite062009
  • signal transducer activity
    		•  0.270054246024761 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.270054246024761 bayes_pls_golite062009
  • MAP kinase activity
    		•  0.08504542461349 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  0.0556163711947139 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.00652065412910241 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle