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Protein Overview: IL8_SHEEP

General Information:
Name(s) found: IL8_SHEEP [Swiss-Prot]
Description(s) found:
Found 10 descriptions.
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  • Interleukin-8 OS=Ovis aries GN=CXCL8 PE=3 SV=1 [Swiss-Prot]
    • Organism: Ovis aries
    Length: 101 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSKLAVALL AAFLLSAALC EAAVLSRMST ELRCQCIKTH STPFHPKFIK ELRVIESGPH  60
   61 CENSEIIVKL TNGKEVCLDP KEKWVQKVVQ AFLKRAEKQD P

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..101] PSI-BLAST 17.39794 NMR STUDY OF MONOMERIC HUMAN INTERLEUKIN-8 (MINIMIZED AVERAGE STRUCTURE)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cytokine activity
    		•  8.07273475133641 bayes_pls_golite062009
  • chemokine receptor binding
    		•  7.19574940007631 bayes_pls_golite062009
  • chemokine activity
    		•  7.19574940007631 bayes_pls_golite062009
  • G-protein-coupled receptor binding
    		•  7.12866319987718 bayes_pls_golite062009
  • receptor binding
    		•  5.98215849587665 bayes_pls_golite062009
  • interleukin-8 receptor binding
    		•  5.16175312638695 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  3.24473914932894 bayes_pls_golite062009
  • binding
    		•  3.18185781962524 bayes_pls_golite062009
  • chemoattractant activity
    		•  3.05299139114464 bayes_pls_golite062009
  • heparin binding
    		•  2.93859357151702 bayes_pls_golite062009
  • protein binding
    		•  2.65575365603289 bayes_pls_golite062009
  • polysaccharide binding
    		•  2.54793646339608 bayes_pls_golite062009
  • pattern binding
    		•  1.02739535268516 bayes_pls_golite062009
  • CCR chemokine receptor binding
    		•  0.697359799598971 bayes_pls_golite062009
  • signal transducer activity
    		•  0.538293194555496 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.538293194555496 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.14673741350408 bayes_pls_golite062009
  • CCR2 chemokine receptor binding
    		•  0.0620912591294003 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle